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27,293 recruiting studies available now

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Maintenance of Effect of NBI-1065845 as an Adjunctive Treatment in Subjects With Major Depressive Disorder (MDD)

The primary objective of this study is to evaluate the efficacy of osavampator (previously NBI-1065845) compared with placebo as an adjunctive treatment in del…

Major Depressive Disorder

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Neurocrine BiosciencesNCT07196501

Longitudinal Natural History Protocol for PRKN- and PINK1-linked PD

Background: Parkinson s disease is a neurologic disorder that affects movement. Its cause is unknown, and it usually begins later in life. Gene changes (PRKN …

PARKINSON DIS

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Neurological Disorders and Stroke (NINDS)NCT07613112

A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations

This study will determine whether patients who have been infected with the Lyme bacteria, Borrelia burgdorferi, and treated with antibiotics still have the bac…

Lyme Disease

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT00001539

Phase 2

A Multi-Center Phase II Study of Selinexor in Treating Recurrent or Refractory Wilms Tumor and Other Pediatric Solid Tumors

The purpose of this study is to find out whether selinexor is an effective treatment for people who have a relapsed/refractory Wilms tumor, rhabdoid tumor, MPN…

Wilms TumorRhabdoid TumorMalignant Peripheral Nerve Sheath Tumors+4 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT05985161

Phase 2

Phase II Trial of Natalizumab for Prevention of Immune Effector Cell Associated Neurologic Syndrome (ICANS) in Patients Treated With Chimeric Antigen Receptor T-Cell Therapy for B-Cell Hematologic Malignancies

This phase II studies how well natalizumab works in preventing immune effector cell associated neurologic syndrome (ICANS) in patients with diffuse large B-cel…

Recurrent Diffuse Large B-Cell LymphomaRecurrent Mantle Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Michigan Rogel Cancer CenterNCT07892027

Phase 1

A Phase 1 Study to Evaluate the Safety and Tolerability of GS-5319 Monotherapy and Combination Therapy in Adults With MTAP-deleted Advanced Solid Tumors

The goal of this clinical study is to learn more about the study drug, GS-5319, its dosing, safety and tolerability when given as a single medication and as a …

Advanced Solid Tumor

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Gilead SciencesNCT07128303

Observational

MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education

The MATAspire intervention is a web-app designed to promote substance misuse prevention education and bolster protective coping skills whereby students complet…

Alcohol UseCannabis UseNicotine Use+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

California State University, NorthridgeNCT06553196

Observational

Development of Neuroimaging Methods to Assess the Neurobiology of Addiction

Background: Abusing alcohol, drugs, and other substances can cause serious health problems. These substances also can affect brain function. Researchers want …

Normal Physiology

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NCT02535702

Observational

Promoting Adolescent Health Behavior Change With Clinically Integrated Sample-Efficient Policy Gradient Methods

As most adolescents visit a healthcare provider once a year, health behavior change interventions linked to clinic-based health information technologies hold s…

Alcohol DrinkingSelf EfficacyAdolescent Behavior+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT04110756

Phase 3

A Randomized, Double-Masked, Multicenter, 3-Arm, Pivotal Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal (IVT) MK-8748 Compared With Aflibercept (2 mg) in Participants With Diabetic Macular Edema (DME)

Researchers are looking for new ways to treat diabetic macular edema (DME). In this trial, researchers want to learn if a trial medicine called MK-8748 can tre…

Diabetic RetinopathyMacular Edema

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07705555

Phase 1

A Phase 1b Trial of CMV-MVA Triplex Vaccine in Haploidentical Stem Cell Donors and Recipients to Enhance CMV-Specific Immunity and Prevent CMV Viremia in Recipients of Hematopoietic Stem Cell Transplant

This phase Ib trial tests the safety, side effects, and how well cytomegalovirus (CMV)-modified vaccinia Ankara (MVA) Triplex vaccine works in enhancing CMV-sp…

Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 PositiveAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+9 more

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Phase 1

A Phase 1b, Open-label, Pilot Study of CLN-978 for the Treatment of Moderate to Severe Systemic Lupus Erythematosus (SLE)

Phase 1b, open-label study of CLN-978 administered subcutaneously in patients with Moderate to Severe Systemic Lupus Erythematosus (SLE).

SLESLE (Systemic Lupus)

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Cullinan Therapeutics Inc.NCT06613360