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27,333 recruiting studies available now

Use of Metformin in Patients With Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms

This is a pilot, open-label clinical trial determining the feasibility of metformin therapy in subjects with pseudomyxoma peritonei (PMP) secondary to appendic…

Appendiceal Mucinous NeoplasmPseudomyxoma Peritonei

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of California, IrvineNCT07693452

Phase 1

Phase I/II Study of Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory (R/R) Myelodysplastic Syndromes (MDS)

The goal of this interventional clinical trial is to evaluate the safety and tolerability of leflunomide in combination with decitabine as treatment for patien…

Myelodysplastic Syndromes

Estimated

~$150 – $3,000

Actual pay is set by the research site.

West Virginia UniversityNCT06923488

Observational

Intracalvarial Prefrontal Cortical Stimulation in Treatment-Resistant Depression

Chronic intracalvarial cortical stimulation is a minimally invasive method involving the neurosurgical placement of an electrode above the inner table of the s…

Depression Severe

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Inner Cosmos IncNCT05393622

Phase 1

Bilateral Orthotopic Lung Transplant in Tandem With CD3+ and CD19+ Cell Depleted Bone Marrow Transplant From Partially HLA-Matched Cadaveric Donors

The purpose of this study is to determine whether bilateral orthotopic lung transplantation (BOLT) followed by cadaveric partially-matched hematopoietic stem c…

Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Paul Szabolcs

Phase 2

A Phase 2, Multicenter, Randomized, Placebo-controlled, Double-blind Study to Investigate the Safety, Pharmacodynamics, and Preliminary Efficacy of S-606001 as an Add-on to Enzyme Replacement Therapy in Patients With Late-onset Pompe Disease

The purpose of this study is to evaluate the safety, pharmacodynamics (PD), and exploratory clinical efficacy of S-606001 in adult participants with LOPD as an…

Pompe Disease

Estimated

~$75 – $3,000

Actual pay is set by the research site.

ShionogiNCT07123155

Phase 3

A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or ALK Inhibitor Therapy Added to Intensive Therapy for Children With Newly Diagnosed High-Risk Neuroblastoma (NBL)

This phase III trial studies iobenguane I-131 or lorlatinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or g…

GanglioneuroblastomaGanglioneuroblastoma, NodularNeuroblastoma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Children's Oncology GroupNCT03126916

Use of Viscoelastic Assays Beyond Coagulation: Pre- and Post-operative TEG

The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and…

Liver CancerEsophageal CancerColorectal Cancer+4 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Colorado, DenverNCT05517811

Phase 1

REPEAT: RE-irradiation With a Partial brEast, Accelerated Technique: A Single-Center, Multi-site, Prospective, Phase I/II Clinical Trial

This study is to determine whether acute treatment-associated adverse events following breast re-irradiation with aPBI are acceptably low and to assess local c…

Breast Cancer Recurrent

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Dartmouth-Hitchcock Medical CenterNCT07612254

Observational

Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options)

The purpose of this study is to determine the most effective family-centered intervention (FCI) for weight loss and obesity prevention in Hispanic families. FC…

ObesityChild ObesityWeight Loss

Estimated

~$10 – $750

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07144800

Phase 1

A Phase 1, Multi-center, Single-dose, Open-label Study to Evaluate the Pharmacokinetics and Safety of Golcadomide (BMS-986369) in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function

The purpose of this study is to assess the pharmacokinetics and safety of golcadomide (BMS-986369) in matched healthy participants with normal renal function, …

Kidney Failure, Chronic

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Bristol-Myers SquibbNCT07763418

Phase 1

A Phase 1, Randomized, Placebo-Controlled, First-in-Human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Orally Administered KT-579 in Healthy Adult Participants

This is a first-in-human study to evaluate safety and tolerability, pharmacokinetics, and pharmacodynamics of single and multiple dose levels of KT-579 in heal…

Healthy Participants

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Kymera Therapeutics, Inc.NCT07412288

Observational

Identifying Challenges to Healthy Aging in Persons With HIV Age 50 and Older

The primary objective of this study is to identify and characterize frailty and pre-frailty in persons age 50 and older living with human immunodeficiency viru…

HIVAging

Estimated

~$10 – $750

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT05858034