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27,370 recruiting studies available now

HM2023-05: GTB-3650 (Anti-CD16/IL-15/Anti-CD33) Tri-Specific Killer Engager (TriKE®) for the Treatment of High Risk Myelodysplastic Syndromes (MDS) and Refractory/Relapsed Acute Myeloid Leukemia (AML)

This is a Phase I dose finding study of GTB-3650 (anti-CD16/IL-15/anti-CD33) Tri-Specific Killer Engager (TriKE®) for the treatment of select CD33-expressing r…

Myeloid MalignancyAcute Myeloid LeukemiaMyelodysplastic Syndromes

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Masonic Cancer Center, University of MinnesotaNCT06594445

Observational

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

The goal of this intervention study is to learn about how weight loss impacts molecular signaling of intermuscular adipose tissue (IMAT) in individuals with ob…

ObesityInsulin SensitivityMuscle Weakness+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Colorado, DenverNCT06129110

Observational

Healthy Family Project: Ending Tobacco Use and Smoke Exposure in Asian American Communities

This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that …

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT07049757

Observational

The Artix All-in-one Solution for Complete thrombEctomy With eNDovascular Approach

This study is a post-market, prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the Artix Thrombectomy System in patients w…

Acute Lower Limb Arterial Occlusion

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Inari MedicalNCT07135895

Phase 2

Tovorafenib for the Treatment of Newly Diagnosed or Recurrent Craniopharyngioma in Children and Young Adults

The current study assesses the tolerability and efficacy of monotherapy with pan-RAF-kinase (Tovorafenib) inhibition for the treatment of children and young ad…

Craniopharyngioma, ChildCraniopharyngiomaRecurrent Craniopharyngioma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Sabine Mueller, MD, PhDNCT05465174

Phase 1

A Phase 1, Open-label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of VVD-130037, a Kelch-like ECH Associated Protein 1 (KEAP1) Activator, in Participants With Advanced Solid Tumors

A FIH dose escalation and dose expansion study to evaluate VVD-130037 in participants with advanced solid tumors as a single agent, and in combination with doc…

Advanced Solid Tumors

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Vividion Therapeutics, Inc.NCT05954312

Observational

Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease

This study aims to determine if improved risk stratification tools and interventions to mitigate malnutrition reduce postoperative risk in patients undergoing …

Inflammatory Bowel Diseases

Estimated

~$10 – $1,125

Actual pay is set by the research site.

NYU Langone HealthNCT06309017

Observational

Interactive Roles of Cardiorespiratory Fitness and Adiposity on Recovery of Impaired Glucose and Vascular Control After Physical Inactivity

The far-reaching negative health effects of the reduced physical activity (RPA) epidemic are often overlooked by the general population and health professional…

Metabolic DisordersPhysical InactivityVascular Disease Risk

Estimated

~$10 – $750

Actual pay is set by the research site.

Miami UniversityNCT06842225

Phase 1

A Phase I/IB Study of Ropeginterferon in Patients With Cutaneous T-Cell Lymphoma (CTCL)

This is a single-center, phase I/IB study to identify the recommended phase II dose of Ropeginterferon-alfa 2b (P1101) in patients with CTCL who have failed at…

Cutaneous T Cell Lymphoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

H. Lee Moffitt Cancer Center and Research InstituteNCT07047885

Observational

An Open-Label Pilot Study of Qualia Senolytic Supplementation for the Attenuation of Systemic Inflammatory Cytokines

This open-label pilot study includes adults aged 45 to 79 residing in the United States. The study will last 7 days. Participants will provide blood samples vi…

Inflammation

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Qualia Life SciencesNCT06953518

Phase 2

A Phase II Study of ASTX727 in Patients With PRC2 Loss Malignant Peripheral Nerve Sheath Tumor (MPNST)

The purpose of this study is to see whether the study drug ASTX727 is an effective treatment for people who have MPNST with a PCR2 mutation. ASTX727 is a comb…

Malignant Peripheral Nerve Sheath Tumors (MPNST)

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT04872543

Phase 1

An Open-Label, Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics of the CTPS1 Inhibitor STP938 in Adult Subjects With Advanced Solid Tumors, With a Safety Expansion in Advanced CTPS2 Null Ovarian Cancer

The Phase 1a part of the study is a dose escalation of STP938 as a monotherapy. The Phase 1b part of the study is a safety expansion cohort of STP938 as a mon…

Solid Tumor

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Step Pharma, SASNCT06297525