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A Phase 3, Multicenter, Double-Masked, Randomized, 3-Arm Parallel Group Study to Evaluate the Efficacy and Safety of Intravitreal OTXTKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic Retinopathy

The purpose of this trial is to study the safety and effectiveness of OTX-TKI (axitinib intravitreal hydrogel) for the treatment of Non-Proliferative Diabetic …

Non-Proliferative Diabetic Retinopathy

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Ocular Therapeutix, Inc.NCT07235085

Phase 3

Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth: A Randomized Clinical Trial

This is a Phase 3a, randomized, parallel-controlled trial designed to compare the early re-initiation of semaglutide, starting two weeks after sleeve gastrecto…

Pediatric ObesityMetabolic and Bariatric SurgerySemaglutide

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Children's Hospital Los AngelesNCT06934655

Observational

Em-power: Maximizing Functional Independence for Children With Severe Cerebral Palsy

For children with severe cerebral palsy, a powered wheelchair (PWC) may provide their only option for functional mobility and independence. PWC use is often re…

Cerebral Palsy

Estimated

~$10 – $750

Actual pay is set by the research site.

Grand Valley State UniversityNCT06347432

Phase 2

A Phase 2, Randomized, Double-blind, Placebo-controlled Pilot Study Assessing the Efficacy, Safety and Tolerability of Orally Administered BMS-986368, a FAAH/MAGL Inhibitor, for the Treatment of Spasticity in Participants With Post-stroke Spasticity

The goal of this clinical trial is to learn if the drug BMS-986368 works to treat post stroke spasticity in adults who have had a stroke. BMS-986368 is a desig…

Post-Stroke Spasticity

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Alberto EsquenaziNCT07704840

Observational

Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines: Trained Human Sensory Panels

Many people, particularly small children, must take drugs in liquid form because they cannot swallow pills or capsules. The bad taste of some liquid drugs can …

Healthy Adults

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Monell Chemical Senses CenterNCT06929455

Phase 3

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Adaptive Study of iSCIB1+ in Combination With Ipilimumab and Nivolumab as First-Line Treatment for Advanced Unresectable Melanoma

This Phase 3 clinical trial is evaluating whether adding iSCIB1+, an investigational DNA-based cancer vaccine, to standard immunotherapy with nivolumab and ipi…

Melanoma (Skin Cancer)Advanced MelanomaMetastatic Melanoma+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Scancell LtdNCT07815574

Phase 1

Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP

Rates of bacterial sexually transmitted infections (STIs) are rising globally, demanding innovative interventions beyond the scope of current efforts to preven…

Sexually Transmitted Diseases, Bacterial

Estimated

~$500 – $6,750

Actual pay is set by the research site.

University of California, San FranciscoNCT06414408

Phase 1

Lidocaine Infusion in Pancreatic Cancer: Translational Studies in a Preclinical Model And Human Subjects

This study elucidates the effects of the intravenous (IV) lidocaine infusion on the biology of pancreatic circulating tumor cells (CTCs) isolated from patients…

Pancreatic Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Illinois at ChicagoNCT04048278

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With Transthyretin-Mediated Amyloidosis With Cardiomyopathy in a Real-World Setting

The purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-C…

Transthyretin Amyloidosis With Cardiomyopathy

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Alnylam PharmaceuticalsNCT07358078

Parkinson's Foundation PD GENEration Genetic Registry

Development of a central repository for PD-related genomic data for future research.

Parkinson's Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Parkinson's FoundationNCT04994015

Breast Cancer-Minimal/Molecular Residual Disease Detection and Therapy Monitoring in Patients with Early Stage TNBC-Phase I (B-STRONGER-I)

A prospective, multicenter, observational study to evaluate the correlation of Molecular Residual Disease (MRD) detection using circulating tumor DNA guided te…

TNBC - Triple-Negative Breast CancerMinimal Residual Disease

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Personalis Inc.NCT06230185

Observational

Improving Chronic Disease Outcomes Across the Lifespan by Addressing Structural Racism

The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with …

HyperlipidemiasDiabetesDepression+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Massachusetts, WorcesterNCT06903897