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A Phase 1, Open-label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of VVD-130037, a Kelch-like ECH Associated Protein 1 (KEAP1) Activator, in Participants With Advanced Solid Tumors

A FIH dose escalation and dose expansion study to evaluate VVD-130037 in participants with advanced solid tumors as a single agent, and in combination with doc…

Advanced Solid Tumors

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Vividion Therapeutics, Inc.NCT05954312

Phase 1

An Open-Label, Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics of the CTPS1 Inhibitor STP938 in Adult Subjects With Advanced Solid Tumors, With a Safety Expansion in Advanced CTPS2 Null Ovarian Cancer

The Phase 1a part of the study is a dose escalation of STP938 as a monotherapy. The Phase 1b part of the study is a safety expansion cohort of STP938 as a mon…

Solid Tumor

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Step Pharma, SASNCT06297525

Observational

Feasibility of Internet-based HIV Prevention Research

The study will use social media to recruit a diverse sample of people who self-report injecting drugs, assessing the feasibility of online assessments and part…

HIV PreventionInjection Drug Use

Estimated

~$10 – $750

Actual pay is set by the research site.

Montefiore Medical CenterNCT07625917

Observational

Evaluation of the Safety and Efficacy of Adjunctive Use of Flaus Electric Flosser and a Manual Toothbrush in Reducing Plaque and Gingivitis: A 30-Day Randomized, Parallel, Controlled Clinical Study

The purpose of this study to evaluate the safety and efficacy of an electric flosser (interproximal cleaning aid), when used with a manual toothbrush and fluor…

GingivitisGingival BleedingDental Plaque

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Flaus, IncNCT07805148

Phase 1

Bone Marrow Derived Stem Cells Mobilization for Treatment of Asherman's Syndrome, Atrophic Endometrium, and Recurrent Implantation Failure

This study will assess the use of autologous bone marrow stem cells mobilization using 1,1'-\[1,4-phenylenebis-(methylene)\]-bis-1,4,8,11-tetraazacyclotetradec…

Asherman SyndromeAtrophic EndometriumRecurrent Implantation Failure

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Hugh TaylorNCT05343572

Observational

Scaling a Parenting Evidence Based Intervention (EBI) for Latinx Youth Mental Health in Primary Care

The goal of this study is to evaluate in an effectiveness-implementation type I hybrid trial, an enhanced version of eHealth Familias Unidas for reducing depre…

Depression, AnxietySuicideDrug Use

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MiamiNCT05426057

Phase 2

Electronic Nose (E-nose) Technology to Assess Pathologic Response and Post- Treatment Progression for Non-small Cell Lung Cancer: a Phase II Study

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain …

Non-Small Cell Lung Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07218601

Expanding Access to Cognitive Health Biomarker Testing at Home

The goal of this observational study is to learn whether at-home blood biomarker testing for Alzheimer's disease risk is feasible and acceptable in older adult…

Mild Cognitive Impairment (MCI)Alzheimer's Dementia (AD)Subjective Cognitive Decline (SCD)+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of VirginiaNCT07594665

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

The goal of this observational study is to learn how two medicines used in routine care-buprenorphine and morphine-affect recovery in newborns (≥36 weeks' gest…

Neonatal Opioid Withdrawal Syndrome

Estimated

~$10 – $1,125

Actual pay is set by the research site.

HELP for NOWS ConsortiumNCT07278375

Phase 1

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis has a poor prognosis with limited treatment options. The Investigator hypothesize hyperpolarized Xe129-MRI can be performed in pa…

Idiopathic Pulmonary Fibrosis

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of VirginiaNCT06853145

Phase 1

A PHASE 1, OPEN-LABEL, SINGLE-DOSE, PARALLEL-COHORT STUDY TO EVALUATE THE PHARMACOKINETICS, SAFETY, AND TOLERABILITY OF PF-07328948 IN ADULTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIRMENT

The purpose of this study is to understand the effects of decreased liver function on the study medicine (PF-07328948). People with decreased liver function ma…

Hepatic ImpairmentHealthy

Estimated

~$500 – $11,250

Actual pay is set by the research site.

PfizerNCT07269301

Phase 1

A Mechanistic Test of Treatment Strategies to Foster Practice Quitting

Tobacco use disorder is a chronic, relapsing health condition that necessitates a chronic care approach. However, traditional smoking cessation treatment progr…

Tobacco UseSmoking CessationSmoking Behaviors+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Rush University Medical CenterNCT05513872