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27,295 recruiting studies available now

MK-5684-004: A Phase 3, Randomized, Open-label Study of Opevesostat Versus Alternative Abiraterone Acetate or Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) That Progressed On or After Prior Treatment With One Next-generation Hormonal Agent (NHA) (OMAHA-004)

The purpose of this study is to assess the efficacy and safety of opevesostat plus daily corticosteroids compared to alternative abiraterone acetate or enzalut…

Metastatic Castration-resistant Prostate Cancer (mCRPC)Prostatic Neoplasms

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT06136650

Phase 1

A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TVB-3567 in Healthy Participants With or Without Acne and to Assess the Effect of Food in Healthy Participants

This is a 4-part study. Part A will be a randomized, double-blind, placebo-controlled investigation of single ascending doses (SAD) to assess the safety, toler…

Acne

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Sagimet Biosciences Inc.NCT06989840

Phase 2

Phase II Study of Nirogacestat in Patients With Kaposi Sarcoma

This phase II trial studies how well nirogacestat works in treating patients with skin Kaposi sarcoma (KS). Several anti-cancer drugs work well in treating KS,…

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AIDS Malignancy ConsortiumNCT07539454

Phase 2

Phase 2 Study of Golcadomide With Rituximab as a Bridging Therapy Prior to CAR-T for Patients With Relapsed or Primary Refractory Aggressive B-Cell Non-Hodgkin Lymphoma (NHL)

This phase II trial tests the effectiveness of golcadomide and rituximab as bridging treatment before chimeric antigen receptor (CAR) T-cell therapy in patient…

Large B-Cell Lymphoma With IRF4 RearrangementRecurrent Aggressive B-Cell Non-Hodgkin LymphomaRecurrent ALK-Positive Large B-Cell Lymphoma+28 more

Phase 3

Randomized, Phase III Study of Early Intervention With Venetoclax and Obinutuzumab Versus Delayed Therapy With Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly…

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04269902

Phase 1

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-Oncology Plasma Cell-Related Diseases

The goal of this clinical study is to learn more about the study drug Anitocabtagene autoleucel (anito-cel), and its safety, tolerability, dosing, and prelimin…

Muscular DiseasesNeuromuscular ManifestationsAutoimmune+4 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Kite, A Gilead CompanyNCT06626919

Phase 1

VRC 329: A Phase I Open-Label, Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (STEMos1) With and Without ALFQ Adjuvant in Healthy Adults

Background: Influenza (flu) is a contagious respiratory illness caused by viruses. Flu symptoms can range from mild to severe, and the illness can be fatal. V…

Influenza PreventionPandemic Influenza Prevention

Estimated

~$500 – $6,750

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT07111078

Observational

The Management of Necrotizing Soft Tissue Infection Wounds With Cytal® Wound Matrix and MicroMatrix®

This is a prospective, pilot, parallel group, randomized controlled trial with 1:1 allocation. This will be a single center study coordinated at the Cleveland …

Necrotizing FascitisNecrotizing Soft Tissue Infection

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Benjamin T. MillerNCT06857708

Phase 2

A Placebo-controlled, Parallel-group, Double Blind, Randomized, Multi-cohort Phase 2 Study to Investigate Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BAY 3670549 in Adult Participants With Atrial Fibrillation.

The main goal of this study is to find out how well BAY 3670549 works, how safe it is, how well people can tolerate it, and how the body handles the medicine. …

Atrial Fibrillation

Estimated

~$75 – $3,000

Actual pay is set by the research site.

BayerNCT07625215

Observational

Cancer Pain 101: A Digital, Asynchronous Intervention of Pain Management in Advanced Cancer

This is a Stage 1 study of a behavioral intervention, which means that a new intervention is being pilot tested to understand whether it is acceptable and feas…

CancerPainAdvanced Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Alabama at BirminghamNCT07852468

Phase 1

Merging Strategy That Uses Gut Microbiome Profiling and Targeted Modulation to Improve CAR-T Cell Therapy Outcomes, Predict Responses, and Reduce Toxicity

Chimeric Antigen Receptor T-Cell (CAR-T) therapy has transformed the management of large B-cell lymphoma, and multiple myeloma by achieving remarkable response…

Lymphoma, B-CellMultiple Myeloma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of ChicagoNCT07871747

Observational

Optimal Targeted High-definition tDCS for Reducing Post-stroke Upper Limb Motor Impairments

Non-invasive, non-pharmaceutical technologies that augment routine clinical practice for brain diseases and manage chronic symptoms have advanced rapidly over …

Hemiparetic Stroke

Estimated

~$10 – $750

Actual pay is set by the research site.

Carle Foundation HospitalNCT07599774