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27,270 recruiting studies available now

Establishing Normative Data for Pupillometer Assessments in Neuro-Intensive Care

The purpose of this study is to collect a large amount of data that may assist in addressing the gap in knowledge of understanding pupillometer readings using …

Critical IllnessNeuropathy

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Texas Southwestern Medical CenterNCT02804438

Phase 1

A Phase 1/2, First-in-human, Multicenter, Open-label Trial Evaluating the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

The primary purpose of Phase 1 is to characterize the safety and tolerability to identify the recommended dose (RD) of Debio 1562M for further development. Th…

Acute Myeloid Leukemia

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Debiopharm International SANCT06969430

Phase 2

A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune syste…

Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)Alopecia Areata

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT05398809

Phase 3

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-1)

The purpose of this study is to evaluate the efficacy and safety of KarXT for the treatment of manic episodes in Bipolar-I Disorder

Bipolar-I Disorder With Mania or Mania With Mixed Features

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Bristol-Myers SquibbNCT06951698

Observational

Mechanistic Validation of Human Multipolar TES-TI: Amplitude Modulation, Frequency, and Benchmarking

This study is to find out whether and how a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interfer…

Transcranial Electric Stimulation

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT07752745

Observational

Thriving in a Digital World: A Mindfulness-Based Pilot to Support Sleep and Mental Health in Teens

The goal of this clinical trial is to understand the feasibility and acceptability on a mindfulness-based intervention to address co-existing smartphone addict…

Depression and/or Anxiety SymptomsProblematic Phone Use Behavior

Estimated

~$10 – $750

Actual pay is set by the research site.

Brown UniversityNCT07892807

Phase 1

Efficacy of Erector Spinae Plane (ESP) Blocks in Free Flap-Based Breast Reconstruction: A Randomized Controlled Study

This study is a prospective randomized controlled trial to assess the efficacy of erector spinae plane (ESP) blocks in patients undergoing autologous free flap…

Breast ReconstructionFree Flap Reconstruction

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Carilion ClinicNCT07891039

Obtaining Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

Background: This study is designed to provide samples to help us study the genes your blood cells are making as well as the proteins, sugars, fats, vitamins a…

Endothelial DysfunctionInflammation in Cardiopulmonary and Vascular Disease StatesHealthy Volunteers

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institutes of Health Clinical Center (CC)NCT03253705

Phase 1

A Phase 1 and Randomized Phase 2 Trial of Selinexor and Temozolomide in Recurrent Glioblastoma

This phase I/II trial tests the safety, side effects and best dose of selinexor given in combination with the usual chemotherapy (temozolomide) and compares th…

Recurrent Glioblastoma, IDH-WildtypeRecurrent MGMT-Methylated Glioblastoma

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05432804

Phase 2

A Phase 2 Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of WIN378 in Participants With Moderate - Severe Chronic Obstructive Pulmonary Disease

This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate - severe chronic obstructive pulmonary disease…

COPD (Chronic Obstructive Pulmonary Disease)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Windward BioNCT07646587

Phase 3

A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Design Trial to Evaluate the Safety and Efficacy of Denifanstat in Participants With Moderate to Severe Acne Vulgaris

The purpose of this study is to evaluate the safety and efficacy of denifanstat compared with matching placebo in participants with moderate to severe acne vul…

Acne Vulgaris

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Sagimet Biosciences Inc.NCT07863193

Phase 3

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial Followed by an Open-Label Extension to Evaluate the Safety and Efficacy of Canvuparatide (MBX 2109) in Adult Patients With Hypoparathyroidism

The purpose of this study is to investigate the efficacy and safety of canvuparatide administered as a once-weekly (QW) treatment to adult study participants w…

Hypoparathyroidism

Estimated

~$50 – $2,100

Actual pay is set by the research site.

MBX BiosciencesNCT07699471