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A Phase 1/2 Study of BMS-986482 as Monotherapy or Combination Therapy in Participants With Advanced Solid Tumors

The purpose of this study is to investigate the safety and efficacy of BMS-986482 alone and as combination therapy in participants with advanced solid tumors.

Advanced Solid Tumors

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Bristol-Myers SquibbNCT06697197

Phase 1

A Placebo-Controlled, Single- and Multiple-Ascending Dose, Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease

The purpose of this study is to see how safe LY4405094 is and to see how much and how quickly LY4405094 gets into the bloodstream. For healthy participants, th…

Healthy VolunteersAlzheimer DiseaseAmyloid+1 more

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Eli Lilly and CompanyNCT07787182

Phase 2

A Phase 2b/3, Multicentre, Randomised, Double-blind, Controlled Trial, With an Open Label Extension, to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

The Redefine Study (COMP202) is testing COMP360 to see if it may reduce post-traumatic stress disorder (PTSD) symptoms when administered alongside monitoring a…

PTSD - Post Traumatic Stress DisorderPTSDPTSD Symptoms+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

COMPASS PathwaysNCT07570654

Phase 2

Phase 2 Study of Glofitamab and Gemcitabine and Oxaliplatin (Glofit-GemOx) Bridging to Lisocabtagene Maraleucel in Relapsed/Refractory Aggressive B-cell Lymphomas

The goal of this clinical trial is to assess the clinical efficacy of bridging therapy with glofitamab/gemcitabine/oxaliplatin (Glofit-GemOx) followed by lisoc…

LymphomaB-cell LymphomasRelapsed/Refractory Large B-cell Lymphoma+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT07711483

A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Bhutanese Community of Central Ohio Health Study to Identify Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating Health Disparities From a Cross-Sectional Study

Background: As of 2021, almost 45 million people in the United States were foreign-born immigrants. South Asians, including people from Bhutan, are the fastes…

Cardiometabolic Risk FactorsMental Health

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Environmental Health Sciences (NIEHS)NCT06991751

Phase 2

Pilot Phase II Trial Evaluating Safety and Feasibility of Neoadjuvant Botensilimab and Balstilimab in Clear Cell Renal Cell Carcinoma (NEO RoBOT)

This phase II trial tests the effect of botensilimab and balstilimab before surgery (neoadjuvant) in treating patients with high-risk clear cell renal cell can…

Clear Cell Renal Cell CarcinomaStage II Renal Cell Cancer AJCC v8Stage III Renal Cell Cancer AJCC v8+1 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07516366

Phase 2

Master Screening and Reassessment Protocol (MSRP) for the NCI MyeloMATCH Clinical Trials

This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participa…

Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative NeoplasmAcute Myeloid Leukemia Post Cytotoxic Therapy+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05564390

Phase 1

A Phase I, Single-Center, Dose Escalation Trial of Heterologous Prime-Boost Vaccination With Ad5.F35-hGUCY2C-PADRE and Lm-GUCY2C Vaccines in Adults With Advanced Colorectal and Small Bowel Adenocarcinomas

This is an open-label, non-randomized, single-center, dose-escalation Phase 1 trial using a heterologous prime-boost strategy of vaccination with Ad5.F35-hGUCY…

Colorectal CancerSmall Bowel Adenocarcinoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Thomas Jefferson UniversityNCT07417488

Observational

Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response

The goal of this study is to investigate whether the therapeutic response of pancreatic tumors can be accurately assessed using quantitative DCE-MRI, when the …

Pancreatic Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Ohio State UniversityNCT04588025

Phase 2

Cashew Allergy Study in Children: Assessing Desensitization, Efficacy, and Safety (CASCADES Study)

The CASCADES study will investigate the safety and efficacy of sublingual immunotherapy (SLIT) for the treatment of cashew allergy in children ages 1-11 years …

Cashew Nut AllergyTree Nut Allergies

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of North Carolina, Chapel HillNCT07170540

Phase 4

Modality Choice Before and After Failure for the Treatment of Painful Diabetic Neuropathy (MCPAIN)

The research team will perform a comparative-effectiveness sequential, multiple assignment, randomized trial in painful diabetic neuropathy (PDN) patients for …

Painful Diabetic Neuropathy (PDN)Diabetic Nephropathies

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of MichiganNCT07795593

Phase 1

Safety of Cultured Allogeneic Adult Umbilical-cord or Placental Derived Mesenchymal Stem Cell Intrathecal Injection for the Treatment of Spinal Cord Injury

This trial will study the safety and efficacy of intrathecal injection of cultured allogeneic adult umbilical-cord or placental derived mesenchymal stem cells …

Spinal Cord Injuries

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT05018793