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27,270 recruiting studies available now

Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders

Study description: This is a natural history study that will evaluate any patient with enzyme or DNA confirmed GM1 or GM2 gangliosidosis, sialidosis or galact…

Neurological RegressionMyoclonusCherry Red Spot+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Human Genome Research Institute (NHGRI)NCT00029965

Observational

High-dose Accelerated Theta Burst Stimulation to Restore PD-induced Motor Network Dysconnectivity

Parkinson disease (PD) is a common disorder in which reduced speed of movement results from inadequate brain production of the chemical dopamine. The most effe…

Parkinson Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MichiganNCT05509842

Observational

Randomized Placebo-controlled Trial of Nicotine Pouches in Smokers

The purpose of this clinical trial is to understand the health effects of a new oral nicotine pouch, and also to understand if this product can help reduce tra…

Tobacco Dependence

Estimated

~$10 – $750

Actual pay is set by the research site.

Milton S. Hershey Medical CenterNCT06043362

Phase 3

A PHASE 3, EXTERNAL AND SYNTHETIC PLACEBO-CONTROLLED RANDOMIZED STUDY WITH DOSE-UP FOR NON-RESPONDERS TO INVESTIGATE SAFETY AND EFFICACY OF RITLECITINIB 50 MG AND 100 MG ONCE DAILY IN ADULT AND ADOLESCENT PARTICIPANTS 12 YEARS OF AGE AND OLDER WITH ALOPECIA AREATA

The purpose of the study is to learn about the safety and effects of the study medicine (called ritlecitinib) for the treatment of alopecia areata. Alopecia ar…

Alopecia Areata

Estimated

~$50 – $2,250

Actual pay is set by the research site.

PfizerNCT06873945

BOdygUardian MOnitoriNg for ReCurrencE of AF (BOUNCE-AF)

The DISRUPT-AF Registry is an observational, prospective, multi-center, non-randomized, real-world registry designed to obtain clinical experience with the FAR…

Atrial Fibrillation (AF)

Estimated

~$10 – $750

Actual pay is set by the research site.

Heart Rhythm Clinical and Research Solutions, LLCNCT07671677

Phase 1

A Phase 1/2 Prospective, Randomized, Double-blind, Placebo-controlled Multi-center Clinical Trial to Determine the Safety and Efficacy of Denosumab in Improving Beta Cell Function and Glycemic Control Among Patients With Type 1 Diabetes

Type 1 diabetes (T1D) arises from abnormal immune cell-mediated injury to beta cells that make insulin. The injured beta cells can then no longer make the need…

Type 1 Diabetes

Estimated

~$150 – $3,000

Actual pay is set by the research site.

City of Hope Medical CenterNCT06524960

Phase 2

A Phase II Study Using Autologous Young Tumor-Infiltrating Lymphocytes Derived From Patients With Non-Small Cell Lung Cancer Following Non-Myeloablative Lymphocyte Depleting Preparative Regimen

Background: The NCI Surgery Branch has developed an experimental therapy that involves taking white blood cells from patients' tumors, growing them in the lab…

Advanced Non-Small Cell Lung CancerSquamous Cell CarcinomaAdvanced NSCLC+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT02133196

Phase 3

A Phase 3, Randomized, Double-blind, Efficacy and Safety Study Comparing Orelabrutinib to Placebo in Patients With Primary Progressive Multiple Sclerosis

Orelabrutinib is a CNS-penetrable BTK inhibitor. This is a phase 3, randomized, double-blind, parallel-group, multicenter study to evaluate the efficacy and sa…

Multiple Sclerosis (MS) Primary Progressive

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Zenas BioPharma (USA), LLCNCT07067463

Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for the Treatment of Skin Ulcer

This trial will study the safety and efficacy of intravenous infusion and intralesional injection of cultured allogeneic adult umbilical cord or placental deri…

Skin Ulcer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT05158127

Phase 1

An Open-label, Multi-center, Phase I/Ib Study of IEV407 as a Single Agent and in Combination With Endocrine Therapy in Patients With Advanced Hormone Receptor Positive, HER2- Negative Breast Cancer

The purpose of this study is to evaluate the safety, tolerability and preliminary activity of IEV407 as a single agent and in combination with endocrine therap…

Advanced HR+/HER2- Breast Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT07604571

Phase 3

A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multicenter Trial to Compare the Efficacy and Safety of a Fixed Dose of SEP-363856 to Placebo in the Treatment of Adults With Generalized Anxiety Disorder

This is a global, phase 3, randomized, double-blind, parallel-group, 2-arm, placebo controlled, multicenter trial designed to compare the efficacy, safety and …

Generalized Anxiety Disorder

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Otsuka Pharmaceutical Development & Commercialization, Inc.NCT07767903

Observational

Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers.

This study develops and tests a dynamic workplace-based depression intervention that is tailored to the specific social and behavioral needs of low-wage hospit…

DepressionPhysical Inactivity

Estimated

~$10 – $750

Actual pay is set by the research site.

San Diego State UniversityNCT06753123