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27,352 recruiting studies available now

Pilot Study to Assess the Contribution of UGT2B17 and Associated Genetic Polymorphisms on the Pharmacokinetics of Diclofenac Alone and Upon Co-administration With Curcumin

The purpose of this pilot study is to gather preliminary data on the (1) contribution of the understudied drug metabolizing enzyme, UDP-glucuronosyltransferase…

Interaction

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Washington State UniversityNCT06053411

Observational

A Prospective Randomized Study of Surgical Site Infection After Linear Repair With or Without Cyanoacrylate Skin Adhesive Following Mohs Micrographic Surgery and Wide Local Excision

This study will compare surgical site infection after linear repair with or without cyanoacrylate skin adhesive following Mohs micrographic surgery or wide loc…

Surgical Site InfectionSkin CancerWound Healing

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MinnesotaNCT07844681

Phase 1

Phase 1/2, Open-Label, Multicenter, Dose Escalation and Expansion Study of BHB810 in Participants With Advanced Gastric and Gastroesophageal Junction Adenocarcinoma

This study is looking at how safe BHB810 is in adults with gastric and gastroesophageal adenocarcinoma (GEJ). The purpose of this study is also to look at: how…

Gastric CancerGastric AdenocarcinomaGastric (Stomach) Cancer+11 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Impact of Collaborative Care for Pregnant Women With Opioid Use Disorder in Low-Resource Obstetric Settings

The investigators seek to adapt a collaborative care model (CCM) for community-based, low-resource obstetric settings and to test the effects of this adapted C…

PregnancyPostpartum PeriodOpioid Use Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PittsburghNCT06956352

Phase 1

A Phase 1/2 Dose Evaluation Trial of the Safety and Preliminary Efficacy of Anti CD19 Allogeneic CRISPR-Cas9-Engineered T Cells (CTX112) in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease

This is a single-arm, open-label, multicenter, ascending dose Phase 1/2 trial evaluating the safety and preliminary efficacy of CTX112 or Zugocabtagene geleuce…

Warm Autoimmune Hemolytic Anemia (WAIHA)ITP - Immune ThrombocytopeniaWarm Autoimmune Hemolytic Anemia+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

CRISPR Therapeutics AGNCT07549698

Phase 1

A Phase I/Ib Dose Escalation Trial of Futibatinib in Combination With Paclitaxel/Ramucirumab in Second Line Confirmed Locally Advanced/Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

This phase I trial tests the safety, side effects and best dose of futibatinib with paclitaxel and ramucirumab for the treatment of patients with gastric, gast…

Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+13 more

Estimated

Phase 1

A Phase 1, First-in-Human, Open Label Study Evaluating Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ABBV-438 in Adult Subjects With Relapsed or Refractory Multiple Myeloma

Multiple myeloma (MM) is a plasma cell disease characterized by the growth of clonal plasma cells in the bone marrow. The purpose of this study is to assess th…

Multiple Myeloma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

AbbVieNCT07409246

Observational

GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)

The investigators propose the Gluten Free Nutrition Optimization through Ultra-processed food Reduction and Improved Strategies for Health (GF-NOURISH) study t…

Celiac Disease in ChildrenNutrition Disorder, Child

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Children's HospitalNCT06356220

Phase 3

A Phase III, Multisite, Randomized, Double-Blind Trial of BNT327 in Combination With Chemotherapy Versus Placebo With Chemotherapy in Patients With Previously Untreated Locally Recurrent Inoperable or Metastatic TNBC Determined Ineligible for PD(L)1 Therapy Based on PD-L1 Negative Disease

This is a Phase III trial where participants will be randomized to two treatment groups, which means participants will be assigned by equal chance to a treatme…

Breast Neoplasms

Estimated

~$50 – $2,250

Actual pay is set by the research site.

BioNTech SENCT07173751

Phase 2

A Randomized, Double-Blind, Placebo-Controlled Mechanistic Study to Assess a Single Oral Dose of CYB003 in Participants With Major Depressive Disorder (MDD) and Moderate to Severe Anxiety

The goal of this study is to learn how psychedelics may help symptoms of depression and anxiety. Participants with major depressive disorder experiencing sympt…

DepressionAnxietyMajor Depressive Disorder

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Ohio State UniversityNCT06820723

Phase 3

A Long-Term Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Multiple Maintenance Doses of Oral Once Daily Aleniglipron for Chronic Weight Management in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

This is randomized, double-blind, placebo-controlled study of the long-term efficacy, safety, and tolerability of multiple doses of aleniglipron in participant…

ObesityOverweightChronic Weight Management+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure TherapeuticsNCT07654374

Wearable Sensor Platform to Monitor Stroke Recovery During Inpatient Rehabilitation

This observational trial seeks to assess the feasibility of using non-invasive, portable, real-time body-worn sensors to continuously monitor, quantify, and in…

Stroke

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Shirley Ryan AbilityLabNCT04219670