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27,377 recruiting studies available now

An Open-Label, Multicenter, Phase Ib Trial Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab as Monotherapy and Cevostamab Plus Pomalidomide and Dexamethasone or Cevostamab Plus Daratumumab and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

This Phase Ib, multicenter, open-label study will evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of cevostamab monotherapy…

Multiple Myeloma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Genentech, Inc.NCT04910568

Phase 1

A Phase 1b/2 Open-label Study Evaluating Different MK-6070 and Ifinatamab Deruxtecan (MK-2400)-Based Regimens in First-line Extensive Stage Small Cell Lung Cancer

Researchers are looking for new ways to treat extensive-stage small cell lung cancer (ES-SCLC). ES-SCLC is a type of lung cancer that has spread throughout the…

Small Cell Lung Cancer Extensive Stage

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07227597

Observational

Preventing Depression of Chinese American Adolescents Through Mobile Health Application

The goal of this clinical trial is to test if a culturally sensitive mobile health application (Relax, Reflect, Empower-RRE) is feasible and effective in promo…

Subclinical Depressive Symptoms

Estimated

~$10 – $750

Actual pay is set by the research site.

Northeastern UniversityNCT05921201

Phase 3

A Randomized, Open-label, Phase 3 Study of Setidegrasib (ASP3082) Versus Docetaxel in Participants With KRAS G12D-mutated Locally Advanced (Unresectable) or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on or After Platinum Based Chemotherapy and Checkpoint Inhibitor Therapy (CPI)

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. The first treatment is usually chemotherapy, given with another treatment that targe…

Non-small Cell Lung Cancer (NSCLC)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT07566052

Phase 4

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients wi…

Post Operative Pulmonary ComplicationsNeuromuscular BlockadeGeneral Anesthesia

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The University of Texas Medical Branch, GalvestonNCT07203287

Phase 1

A Phase 1b, Randomized, Placebo-Controlled, Participant and Investigator-Blinded, Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Cytochrome P450 Interaction of Orally Administered LY3873862 in Participants With Sporadic or Familial Amyotrophic Lateral Sclerosis

The main purpose of this study in participants with Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS) is to test the safety of different doses and to de…

Amyotrophic Lateral SclerosisCytochrome P-450 Enzyme System

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Eli Lilly and CompanyNCT07883590

Observational

The Effects of Vagus Nerve Stimulation on Intrinsic Lower Leg Spinal Motoneuron Excitability in Parkinson's Disease.

This study is designed to better understand the mechanisms contributing to impaired activation of leg muscles in people with Parkinson's disease (PD) and to te…

PARKINSON DISEASE (Disorder)Parkinson's Disease (PD)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MinnesotaNCT07226284

Phase 1

First in Human Phase 1 Study of AOH1996 in Patients With Refractory Solid Tumors

This phase I trial studies the side effects and best dose of AOH1996 in treating patients with solid tumors that do not respond to treatment (refractory). AOH1…

Refractory Malignant Solid NeoplasmOsteosarcomaLeiomyosarcomas+4 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

City of Hope Medical CenterNCT05227326

Umbrella Long-Term Follow-Up Protocol

This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology…

Hematopoietic Cell Transplantation RecipientLeukemiaSolid Tumor

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Children's Oncology GroupNCT00736749

Observational

STOP (Shared Decision Making to Treat Or Prevent) HIV in Criminal Legal Involved Populations

This study seeks to compare the effectiveness of two Patient Navigation models of care to evaluate the proportion who initiate PrEP/ART and substance use/subst…

Substance Use Disorders

Estimated

~$10 – $750

Actual pay is set by the research site.

Yale UniversityNCT07223398

Phase 1

Open Label, Multicenter, Dose-escalation and Cohort-expansion Phase I/IIA Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer (CRC) - BreAK CRC Trial (BreAK for Brenus Anti-cancer)

This is a phase I/IIA, first-in-human (FIH), two-part, open-label, multicenter study to characterize the safety, tolerability profile, and clinical efficacy of…

Unresectable Metastatic Colorectal CancerUnresectable Locally Advanced Colorectal Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Brenus PharmaNCT06934538

Phase 2

A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy

Background: Prostate cancer is often treated with radiation and ADT (ADT is androgen deprivation therapy). Up to 30% of these cancers recur within 5 years of …

Cancer Of Prostate

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05361798