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Phase 1/1b Safety and Tolerability Trial of CD19 Directed CAR T Cells in Adult Patients With B-Cell Acute Lymphoblastic Leukemia (B-ALL) With Minimal Residual Disease (MRD) Positivity at First Complete Remission

This open-label, single arm Phase 1/1b trial aims to determine the safety and tolerability of anti-CD19 chimeric antigen receptor-expressing (CAR) T cells (UCD…

Acute Lymphoid LeukemiaAcute Lymphoblastic Leukemia

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Colorado, DenverNCT05535855

Phase 1

Phase 1, Double-Blinded, Placebo-Controlled, Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) Safety and Pharmacokinetics Trial of AVR-48

This is a Phase 1 (healthy adult volunteers), 2-part, double-blind, randomized, placebo controlled trial to evaluate the safety and pharmacokinetic (PK) profil…

Safety IssuesTolerabilityPharmacokinetics+1 more

Estimated

~$500 – $10,500

Actual pay is set by the research site.

AyuVis Research, Inc.NCT06847698

Phase 2

Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial): A Prospective Randomized Controlled Trial

The central hypothesis of this research study is that perioperative administration of the proton pump inhibitor (PPI) pantoprazole could reduce the development…

Acute Kidney Injury

Estimated

~$75 – $2,000

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT06706258

Phase 1

A Master Protocol for the Multi-cohort, Open-label, Phase 1/2 Study of DCC-3009 in Participants With Gastrointestinal Stromal Tumor (GIST)

The purpose of this Phase 1/2 master protocol study is to evaluate if DCC-3009 is safe, tolerable and works effectively in the treatment of GIST. The study wil…

Gastrointestinal Stromal Tumor (GIST)

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Deciphera Pharmaceuticals, LLCNCT06630234

Endoscopic Retrograde Cholangiopancreatography Patient Registry

The risk of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis(PEP) is influenced by patient and procedure-related factors. Strategies to d…

Gastro-Intestinal Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

Methodist Health SystemNCT07490132

Observational

HeartLogic Optimization of CHF Medications in Chronic Low EF Population: A Follow-on Study

The goal of this trial is to determine if the addition of the Heart Logic diagnostic alerts to standard of care therapies will lessen hospitalizations and impr…

Congestive Heart Failure ChronicLow Ejection Fraction

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Robert PickettNCT07412626

Understanding Engagement Trends in Chondrosarcoma Clinical Trials: Investigating Participation Patterns Among Chondrosarcoma Patients

Taking part in medical research usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect …

Chondrosarcoma

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Power Life Sciences Inc.NCT06029478

Phase 2

A Phase II, Multicentre, Open-label, Master Protocol to Evaluate the Efficacy and Safety of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination With Anticancer Agents in Patients With Advanced/Metastatic Solid Tumours

TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination w…

Endometrial CancerGastric CancerMetastatic Castration-resistant Prostate Cancer+4 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AstraZenecaNCT05489211

Phase 1

A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors

Background: Neuroendocrine neoplasms (NENs) are rare cancers in the gastrointestinal tract, pancreas, lungs, adrenal glands, and other areas of the body. Many…

Neuroendocrine CarcinomasNeuroendocrine TumorsCarcinoma, Neuroendocrine+2 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06041516

Observational

The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults

This is a single-center prospective cohort study to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.

Kidney StonesUrine Specimen Collection

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ChicagoNCT07389226

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 followi…

LVADFrailtyGI Bleed+5 more

Estimated

~$10 – $750

Actual pay is set by the research site.

International Consortium of Circulatory Assist CliniciansNCT06039176

Observational

Metabolic Diet for Relapse Prevention in Anorexia Nervosa

This is an interventional study that will test the safety, tolerability, and efficacy of the Metabolic Diet, which was designed as a treatment for women with a…

Anorexia Nervosa

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT05197309