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27,333 recruiting studies available now

Intracalvarial Prefrontal Cortical Stimulation in Treatment-Resistant Depression

Chronic intracalvarial cortical stimulation is a minimally invasive method involving the neurosurgical placement of an electrode above the inner table of the s…

Depression Severe

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Inner Cosmos IncNCT05393622

Phase 1

Phase Ib Study of Anti-CD3 x Anti-CD33 Bispecific Antibody (CD33Bi) Armed Fresh Peripheral Blood Mononuclear Cells (CD33 FPBMC) in Patients With Measurable Residual Disease (MRD)+ Acute Myeloid Leukemia or Myelodysplastic Syndrome

The purpose of this study is to understand the safety and estimate the efficacy of combining anti-CD3 x anti-CD33 bispecific antibody (CD33Bi) armed fresh peri…

Acute Myeloid LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasm

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of VirginiaNCT07270978

Phase 2

A Phase 2, Multicenter, Randomized, Placebo-controlled, Double-blind Study to Investigate the Safety, Pharmacodynamics, and Preliminary Efficacy of S-606001 as an Add-on to Enzyme Replacement Therapy in Patients With Late-onset Pompe Disease

The purpose of this study is to evaluate the safety, pharmacodynamics (PD), and exploratory clinical efficacy of S-606001 in adult participants with LOPD as an…

Pompe Disease

Estimated

~$75 – $3,000

Actual pay is set by the research site.

ShionogiNCT07123155

Phase 3

A Phase 3, Multicenter, Randomized, Controlled, Open-Label Clinical Trial of Aglatimagene Besadenovec (CAN-2409) Plus Prodrug and Pembrolizumab Versus Docetaxel for Stage IV Non-Squamous Non-Small Cell Lung Cancer Progressing on Pembrolizumab-based Treatment

This phase III trial compares the effect of the combination of aglatimagene besadenovec and pembrolizumab versus standard of care docetaxel chemotherapy for th…

Non-squamous, Non-Small Cell Lung Cancer

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Candel Therapeutics, Inc.NCT07660094

The Role of Visual Attention and Environmental Complexity in Real-world Mobility for People With Lower Limb Amputation

Despite high medical expenses (\>$500K/patient), mobility improvements achieved during rehabilitation for people with lower limb amputation (LLA) fail to trans…

Lower Limb Amputation

Estimated

~$10 – $750

Actual pay is set by the research site.

Virginia Commonwealth UniversityNCT07831707

Edwards PASCAL Transcatheter Tricuspid Valve Repair System Coverage With Evidence Development Study (The CLASP III TR CED Study)

This Coverage with Evidence Development (CED) study measures the long-term health outcomes of patients with severe, symptomatic Tricuspid Regurgitation who rec…

Tricuspid RegurgitationHeart Valve DiseasesHeart Diseases+2 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Edwards LifesciencesNCT07859709

Phase 2

Geriatric Assessment-Guided Treatment Selection in Older Adults With Acute Myeloid Leukemia (The ALIGN-AML Trial)

This is a phase 2 randomized controlled trial to evaluate whether a geriatric assessment (GA)-guided treatment strategy reduces treatment-related toxicity and …

Acute Myeloid Leukemia

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of RochesterNCT07735208

Phase 3

A Phase III Open-Label, Multicenter, Randomized, Controlled Clinical Trial to Evaluate the Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Mixed-Depth, Full-Thickness Burn Wounds as an Alternative to Autografting

To evaluate the safety and efficacy of realSKIN® to provide complete wound closure of mixed-depth, full-thickness burn wounds as an alternative treatment to au…

Burns Degree ThirdBurn (Disorder)Burn Degree Second+2 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

XenoTherapeutics, Inc.NCT06223269

ViBandz Feasibility Study in the Neurological Pediatric Population

This is a single site, mixed methods, feasibility study of the ViBandz device at a Midwest pediatric tertiary care hospital in a physical and occupational ther…

PediatricsNeurologic DysfunctionVibration Therapy

Estimated

~$10 – $750

Actual pay is set by the research site.

Children's Mercy Hospital Kansas CityNCT07458568

Observational

Enhancing Parkinson's Disease Rehabilitation Through Remote Haptic Guidance: Field Study

Individuals with Parkinson's Disease (PD) often have motor difficulties that can negatively impact daily activities and their quality of life. Research has sho…

Parkinson's Disease (PD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Virginia Polytechnic Institute and State UniversityNCT07457710

Phase 1

A Phase 1, Randomized, Placebo-Controlled, First-in-Human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Orally Administered KT-579 in Healthy Adult Participants

This is a first-in-human study to evaluate safety and tolerability, pharmacokinetics, and pharmacodynamics of single and multiple dose levels of KT-579 in heal…

Healthy Participants

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Kymera Therapeutics, Inc.NCT07412288

Phase 2

IIT2022-05-Sankar-BELIEVE: Phase II Study of Bevacizumab in Combination With Chemoimmunotherapy and Maintenance Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

This clinical trial aims to assess whether the addition of bevacizumab to atezolizumab and chemotherapy can improve response to treatment and progression-free …

Extensive-stage Small-cell Lung CancerLiver Metastases

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Kamya SankarNCT05588388