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A Phase 3, Multicenter, Randomized, Controlled, Open-Label Clinical Trial of Aglatimagene Besadenovec (CAN-2409) Plus Prodrug and Pembrolizumab Versus Docetaxel for Stage IV Non-Squamous Non-Small Cell Lung Cancer Progressing on Pembrolizumab-based Treatment

This phase III trial compares the effect of the combination of aglatimagene besadenovec and pembrolizumab versus standard of care docetaxel chemotherapy for th…

Non-squamous, Non-Small Cell Lung Cancer

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Candel Therapeutics, Inc.NCT07660094

Phase 1

A Phase 1A/B Study To Evaluate The Safety And Tolerability Of EBC-129 As A Single Agent And In Combination With Pembrolizumab In Advanced Solid Tumours

This study will assess the safety and tolerability of EBC-129 as a single agent and in combination with pembrolizumab in patients with advanced solid tumours

Advanced Solid Tumours

Estimated

~$150 – $4,500

Actual pay is set by the research site.

EDDC (Experimental Drug Development Centre), A*STAR Research EntitiesNCT05701527

Observational

Recovery From Post-Stroke Aphasia With rTMS Targeting the Anterior Temporal Lobe: Interhemispheric Activation Changes and Lesion-Connectome-Based Predictive Outcomes

This project aims to tailor repetitive Transcranial Magnetic Stimulation (rTMS) target to the clinical profile of post-stroke aphasia, specifically focusing on…

StrokeAphasia

Estimated

~$10 – $750

Actual pay is set by the research site.

University of South CarolinaNCT07608588

Phase 3

Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults With Severe Hypertriglyceridemia at High Risk of Acute Pancreatitis (SHASTA-5 Study)

This study will evaluate the efficacy and safety of plozasiran in approximately 288 adult participants with severe hypertriglyceridemia (SHTG) and history of a…

Severe Hypertriglyceridemia

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Arrowhead PharmaceuticalsNCT06880770

Phase 1

Phase I/II Study of Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory (R/R) Myelodysplastic Syndromes (MDS)

The goal of this interventional clinical trial is to evaluate the safety and tolerability of leflunomide in combination with decitabine as treatment for patien…

Myelodysplastic Syndromes

Estimated

~$150 – $3,000

Actual pay is set by the research site.

West Virginia UniversityNCT06923488

Rare Kidney Stone Consortium Biobank, Rare Diseases Clinical Research Network

This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent…

Primary HyperoxaluriaDent DiseaseAPRT Deficiency+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT02026388

Body Surface Gastric Mapping in Patients With Dyspeptic Symptoms: Recordings at Baseline and on Medical Therapy

Functional dyspepsia and gastroparesis are common stomach disorders with symptoms like early satiety, nausea, and abdominal pain, and are often evaluated with …

GastroparesisFunctional Dyspepsia

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Auckland, New ZealandNCT06854120

Phase 2

A Multi-center, Randomized (1:1), Controlled Phase II Trial of STIMULAN VG With Debridement and a Course of Systemic Antibiotics vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.

The purpose of this trial is to assess the safety, tolerability and between-group effect size of STIMULAN VG (with debridement) and a course of systemic antibi…

Pressure Ulcer, Stage IVOsteomyelitis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Biocomposites LtdNCT06283979

Phase 1

Bilateral Orthotopic Lung Transplant in Tandem With CD3+ and CD19+ Cell Depleted Bone Marrow Transplant From Partially HLA-Matched Cadaveric Donors

The purpose of this study is to determine whether bilateral orthotopic lung transplantation (BOLT) followed by cadaveric partially-matched hematopoietic stem c…

Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Paul Szabolcs

Analysis of Human ALS Tissues and Registry of ALS Patients

Amyotrophic Lateral Sclerosis (ALS), often referred to as Lou Gehrig's Disease, is a progressive, terminal condition of muscle weakness that is associated with…

Amyotrophic Lateral Sclerosis

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Illinois at ChicagoNCT05067179

Observational

Strong Survivors: A Prospective Study of Video-assisted Exercise Program for the Breast Cancer Survivors

The investigators cancer rehabilitation/recovery program, Strong Survivor, has been designed to be delivered digitally, and while there are many such programs …

Mastectomy

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, San DiegoNCT07071896

Observational

Using Real Time Mobile Health Approaches to Understand and Promote Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherenc…

Acute Lymphoblastic LeukemiaLymphoblastic Lymphoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT03932903