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27,295 recruiting studies available now

A Randomized Phase 2/3 Study Evaluating the Safety and Efficacy of Pivekimab Sunirine (PVEK) in Combination With Venetoclax and Azacitidine in Adult Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) Ineligible to Receive Intensive Chemotherapy

Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably. Acute myeloid leukemia (AML) is a cancer of the blood and b…

Acute Myeloid Leukemia

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT07581002

Phase 1

A Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Primary Brain Tumors

This pilot study will assess the safety and feasibility of using an implantable microdevice to measure local intratumor response to chemotherapy and other clin…

Grade II GliomaGrade III GliomaGrade IV Glioma+5 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Oliver JonasNCT04135807

Phase 3

A Randomized, Controlled, Partially Masked, Phase 3b Study to Assess the Injection Burden, Efficacy, Safety, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec (ABBV-RGX-314) in a Real-World Context in Subjects With Neovascular Age-Related Macular Degeneration (nAMD)

Neovascular age-related macular degeneration (nAMD), also known as "wet" AMD, is the abnormal growth of new blood vessels in the light-sensitive tissue at the …

Neovascular Age-related Macular Degeneration

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AbbVieNCT07007065

Observational

Deep Brain Stimulation of the Deep Cerebellar Nuclei in Subjects With Spinocerebellar Ataxia: A Safety and Feasibility Study

The purpose of this study is to evaluate the safety and feasibility of deep brain stimulation (DBS) in the deep cerebellar nuclei (DCN) in patients with Spinoc…

Spinocerebellar Ataxia Genotype Type 1Spinocerebellar Ataxia Genotype Type 3

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Gordon H. BaltuchNCT07752095

Phase 1

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Background: People with alcohol use disorder (AUD) also often have bouts of depression called major depressive episodes (MDEs). People having MDEs have been f…

Alcohol Use Disorder

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute of Mental Health (NIMH)NCT06795581

Phase 4

A Phase 4 Study Evaluating Moderate to Severely Active Ulcerative Colitis or Crohn's Disease and the Use of Vedolizumab Subcutaneous Within a Community Setting

Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (inflammation), bleeding from the anus, …

Ulcerative ColitisCrohn's Disease

Estimated

~$25 – $1,500

Actual pay is set by the research site.

TakedaNCT06581328

Phase 3

A Randomized, Open-label, Phase 3 Study of Setidegrasib (ASP3082) Versus Docetaxel in Participants With KRAS G12D-mutated Locally Advanced (Unresectable) or Metastatic Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on or After Platinum Based Chemotherapy and Checkpoint Inhibitor Therapy (CPI)

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. The first treatment is usually chemotherapy, given with another treatment that targe…

Non-small Cell Lung Cancer (NSCLC)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT07566052

Phase 4

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients wi…

Post Operative Pulmonary ComplicationsNeuromuscular BlockadeGeneral Anesthesia

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The University of Texas Medical Branch, GalvestonNCT07203287

Phase 1

A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma.

This is a Phase 1, open-label, dose-escalation study of CBX-663 in participants with R/R AML, MDS or CMML (Cohort A), advanced solid tumors (Cohort B), or recu…

Advanced Solid TumorsRecurrent or Progressive GlioblastomaRelapse or Refractory Myeloid Malignancies

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Crossbow Therapeutics, Inc.NCT07779798

Phase 2

An Open-label, Multicenter Study to Assess the Effect of Zigakibart Treatment on Histologic, Circulating, and Excreted Markers of Kidney Disease and Dysfunction in Adult Patients With IgA Nephropathy.

The purpose of the study is to assess the effect of zigakibart on IgA nephropathy (IgAN) disease progression.

Immunoglobulin A Nephropathy (IgAN)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT07146906

Phase 2

Effects of Ketone Supplementation on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder

This is a randomized, double-blind, crossover trial to evaluate the immediate effects of a nutritional ketone supplement, Kenotic compared to placebo on brain …

Alcohol Use DisorderKetosis

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of PennsylvaniaNCT06807918

Observational

I CARE (Immunotherapy Cutaneous Adverse Events REsearch) - A Trial With Diverse Cancer Patients to Determine the Impact of SDoH and Side Effects Navigation Program on Treatment Continuation

The purpose of this study is to find out if the navigation program helps participants manage immunotherapy treatment better than usual care. Investigators will…

Kidney CancerBladder CancerBreast Cancer+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07646847