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27,370 recruiting studies available now

Phase I Trial: CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy With Adjuvant Reirradiation for Recurrent High-Grade Glioma and Newly Diagnosed Diffuse Midline Glioma/Diffuse Intrinsic Pontine Glioma in Children and Young Adults

This is a single center Phase I study of a new adjuvant CD200 activation receptor ligand, CD200AR-L, in combination with imiquimod and GBM6-AD vaccine to treat…

Diffuse Midline Glioma, H3 K27M-MutantRecurrent High Grade Glioma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

OX2 TherapeuticsNCT06305910

Phase 1

Safety, Tolerability, Outcomes of Psilocybin for Depression (STOP Depression) in Veterans With Spinal Cord Injury

The main goal of this study is to determine if psilocybin is safe for use in people with SCI. The study will measure how people with SCI respond to three psilo…

Spinal Cord InjuryDepression - Major Depressive DisorderVeteran

Estimated

~$150 – $2,700

Actual pay is set by the research site.

James J. Peters Veterans Affairs Medical CenterNCT07251491

Phase 4

Systemic Vancomycin Levels in Intraosseous Administration During Total Knee Arthroplasty

This is a prospective, single-center, open-label study evaluating systemic vancomycin levels following preoperative intraosseous administration in patients und…

Total Knee Arthroplasty

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of California, San DiegoNCT07633418

Phase 3

Use of 18F-Fluciclovine PET for Discerning Tumor From Treatment Change in Patients With Brain Metastases Undergoing Immunotherapy

The goal of this clinical trial is to use new imaging methods to help in finding out whether the imaging shows that there is a tumor in people with a brain met…

Brain MetastasisRadiation TherapyImmunotherapy, Active

Estimated

~$50 – $1,500

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT06159335

Observational

A Randomized, Sham Controlled Trial of Dorsal Root Rhizotomy Stereotactic Radiosurgery Versus Standard of Care for Spasticity Associated With Stroke, Spinal Cord Injury & Cerebral Palsy

A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurge…

Spasticity as Sequela of StrokeSpastic Cerebral PalsySpasticity, Muscle

Estimated

~$10 – $750

Actual pay is set by the research site.

Ohio State UniversityNCT06070233

Observational

Molecular Imaging of Primary Amyloid Cardiomyopathy

Cardiac amyloidosis is a major cause of early treatment-related death and poor overall survival in individuals with systemic light chain amyloidosis. This proj…

Amyloidosis, PrimaryCardiomyopathy

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT02641145

Phase 2

A Phase 2, Open-Label, Multicenter, Randomized Study Evaluating Neoadjuvant Therapy Targeting the Adenosine Immunosuppressive Pathway in Combination With Immune Checkpoint Blockade and Radiation Therapy in Patients With Advanced PANCreatic Ductal Adenocarcinoma Who Are Candidates for Surgical Resection

The purpose of this study is to combine standard radiation therapy with drugs that encourages the body's immune system against cancer cells and simultaneously …

Pancreatic Ductal Adenocarcinoma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Gulam ManjiNCT06048484

Machine Learning Approaches to Personalized Therapy for Advanced Non-small Cell Lung Cancer With Real-World Data

This research will leverage machine learning (ML) and causal inference techniques applied to real-world data (RWD) to generate evidence that personalizes treat…

Non-small Cell Lung Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of UtahNCT06934343

Phase 2

A Pilot Clinical Trial of Vemurafenib and Cobimetinib as a Redifferentiation Strategy in High-Risk, Radioactive Iodine (RAI) Naïve, BRAFV600E Mutated Differentiated Thyroid Carcinoma Patients Undergoing Initial RAI Therapy

This phase II trial tests how well vemurafenib and cobimetinib work in treating patients with high risk differentiated thyroid carcinoma with BRAFV600E mutatio…

Thyroid Gland Follicular CarcinomaThyroid Gland Oncocytic CarcinomaThyroid Gland Papillary Carcinoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

City of Hope Medical CenterNCT06440850

Observational

Alaska Native Family-Based, Financial Incentives Intervention for Smoking Cessation: An RCT

The current study will conduct an RCT to evaluate the effectiveness of a family-based incentive intervention with Alaska Native/American Indian families. The e…

Smoking Cessation

Documented

Up to $750

Mayo ClinicNCT06556433

Phase 1

A Single and Repeat Dosing and Expansion Study of the Safety, Drug Exposure and Clinical Activity of R-5780 in Combination With a PD-1 (Checkpoint Protein on Immune Cells Called T Cells) Pathway Checkpoint Inhibitor in Patients With Solid Tumors

The goal of this study is determine the safety and tolerability of orally taken probiotic (R-5780) in patients currently on a PD-1 Pathway Checkpoint Inhibitor…

Solid Tumor, AdultSolid TumorMelanoma+3 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Rise Therapeutics LLCNCT06398418

A Single-Center Observational Biomarker Investigation of Response to Bacteriophage Treatment for Bacterial Infection

This study aims to identify biomarkers associated with response to phage therapy for refractory bacterial infections. This includes mycobacteriophage treatment…

Nontuberculous Mycobacterial Lung Disease

Estimated

Pay not disclosed — ask the coordinator

NYU Langone HealthNCT07076238