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27,370 recruiting studies available now

Efficacy of Perioperative Opioid Sparing Techniques on Time to Initiation of Chemotherapy: A Randomized Single Blinded Control Study

The primary purpose of this study is to determine if intrathecal morphine (ITM) administration is superior to quadratus lumborum block or surgeon administered …

Perioperative Opioid Sparing Techniques

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Tennessee Graduate School of MedicineNCT07153614

Observational

Rough Journey to Menopause: How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?

The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and qua…

Iron Deficiency Anemia TreatmentIron DeficiencyIron Deficiency (Without Anemia)

Estimated

~$10 – $750

Actual pay is set by the research site.

Purdue UniversityNCT06798584

Phase 2

Open-label Phase 2 Trial of AMB-05X for Patients With ctDNA(+) Colorectal Cancer After Curative-intent Treatment

To investigate the efficacy of AMB-05X in patients with CRC with MRD as determined by a ctDNA(+) blood test and no clinically detectable radiographic disease.

Colorectal Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT06617858

Phase 1

A Pilot Study Comparing Neoadjuvant and Adjuvant GVAX vs a Mutated KRAS Peptide Vaccine Given With Anti-PD-1 and Anti-CD137 for the Treatment of Surgically Resectable Pancreatic Adenocarcinoma

The purpose of this study is to determine the optimal dose of AGEN2373 that is safe when given in combination with balstilimab and Pancreatic GVAX Whole Cell V…

Pancreatic Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT06782932

Mayo Clinic Precure - Prospective Study

The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and e…

Genetic PredispositionExposure, Environmental

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07332598

Phase 2

The Role of Inflammation in Central Nervous System (CNS) Mechanisms of Anhedonia and Psychomotor Slowing in Depressed People With HIV

The purpose of this 10-week, double-blind, placebo-controlled study is to determine whether inflammation impacts reward and motor neural circuitry to contribut…

HIVDepressionAnhedonia

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Emory UniversityNCT05849038

Observational

Trauma Recovery Via EEG and Actigraphy Tracking (TREAT): Biomarkers of Written Exposure Therapy in PTSD

Posttraumatic stress disorder, or PTSD, can affect emotional health, sleep, daily functioning, and quality of life. Written Exposure Therapy is a brief trauma-…

Posttraumatic Stress Disorder (PTSD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Mclean HospitalNCT07766798

Phase 1

A Phase IA/IB Trial of Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies and HER2 Negative Breast Cancer

Leflunomide in patients with PTEN-Altered advanced solid tumors or HER2 negative breast cancer. Phase 1A objectives are to determine the safety, tolerability, …

PTEN-Altered Advanced Solid Tumors and HER2 Negative Breast Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Deborah DoroshowNCT04997993

Use of Shear Wave Elastography for Intraoperative Brain and Tumor Stiffness Measurements

This study investigates the role of intraoperative shear wave elastography ultrasound (ISWEU) in identifying healthy brain and tumor tissue stiffness differenc…

Brain TumorRecurrent Brain TumorBrain Neoplasm+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT06630338

Phase 1

A Phase I/II Study of Complement Inhibition in Pancreatic Ductal Adenocarcinoma

This phase I/II trial tests the effect of pegcetacoplan in combination with oxaliplatin, irinotecan, leucovorin, and fluorouracil (mFOLFIRINOX) in treating pat…

Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Roswell Park Cancer InstituteNCT07214298

Molecular and Behavioral Characterization of Post-Operative Sensory Outcomes in Individuals With Chronic Pain or Persistent Opioid Use

The incidence and severity of postoperative pain after spine surgery are notably high, often requiring intensive management and potentially affecting the patie…

Post Operative PainOpioid Use, Unspecified

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Medical CenterNCT06639438

Phase 3

A Randomized Phase III Study Comparing Temporally-Modulated Pulsed Radiation Therapy (TMPRT) Versus Standard Radiation Therapy With Temozolomide for Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma

This phase III trial compares temporally-modulated pulsed radiation therapy versus standard radiation therapy in treating patients with newly diagnosed, IDH wi…

Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

NRG OncologyNCT07452458