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27,370 recruiting studies available now

A Pilot Study Comparing Neoadjuvant and Adjuvant GVAX vs a Mutated KRAS Peptide Vaccine Given With Anti-PD-1 and Anti-CD137 for the Treatment of Surgically Resectable Pancreatic Adenocarcinoma

The purpose of this study is to determine the optimal dose of AGEN2373 that is safe when given in combination with balstilimab and Pancreatic GVAX Whole Cell V…

Pancreatic Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT06782932

Mayo Clinic Precure - Prospective Study

The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and e…

Genetic PredispositionExposure, Environmental

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07332598

Phase 2

The Role of Inflammation in Central Nervous System (CNS) Mechanisms of Anhedonia and Psychomotor Slowing in Depressed People With HIV

The purpose of this 10-week, double-blind, placebo-controlled study is to determine whether inflammation impacts reward and motor neural circuitry to contribut…

HIVDepressionAnhedonia

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Emory UniversityNCT05849038

Observational

Trauma Recovery Via EEG and Actigraphy Tracking (TREAT): Biomarkers of Written Exposure Therapy in PTSD

Posttraumatic stress disorder, or PTSD, can affect emotional health, sleep, daily functioning, and quality of life. Written Exposure Therapy is a brief trauma-…

Posttraumatic Stress Disorder (PTSD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Mclean HospitalNCT07766798

Use of Shear Wave Elastography for Intraoperative Brain and Tumor Stiffness Measurements

This study investigates the role of intraoperative shear wave elastography ultrasound (ISWEU) in identifying healthy brain and tumor tissue stiffness differenc…

Brain TumorRecurrent Brain TumorBrain Neoplasm+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT06630338

Phase 3

A Randomized Phase III Study Comparing Temporally-Modulated Pulsed Radiation Therapy (TMPRT) Versus Standard Radiation Therapy With Temozolomide for Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma

This phase III trial compares temporally-modulated pulsed radiation therapy versus standard radiation therapy in treating patients with newly diagnosed, IDH wi…

Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

NRG OncologyNCT07452458

Phase 1

A Phase I/II Study of Complement Inhibition in Pancreatic Ductal Adenocarcinoma

This phase I/II trial tests the effect of pegcetacoplan in combination with oxaliplatin, irinotecan, leucovorin, and fluorouracil (mFOLFIRINOX) in treating pat…

Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Roswell Park Cancer InstituteNCT07214298

Phase 2

Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial

1\. Efficacy of PULSAR preoperative radiation 2. Evaluate potential of microbubble CEUS as an alternative to operative SLNBx 3. Evaluate potential of OA to eva…

Breast Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Texas Southwestern Medical CenterNCT06444269

Phase 4

Post-Prandial Carbohydrate Metabolism in Individuals With and Without Post-Bariatric Surgery Hypoglycemia (PBH)

In this study, the investigators will determine (a) whether metabolism (secretion and turnover) of glucagon is altered in patients with PBH, (b) whether this i…

HypoglycemiaHypoglycemia, ReactiveBariatric Surgery

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Joslin Diabetes CenterNCT07818707

Phase 1

A Phase 1/1b Study of IAM1363 in Participants With Advanced Cancers Harboring HER2 Alterations

This is a Phase 1/1b open-label, multi-center dose escalation and dose optimization study designed to evaluate the safety and preliminary efficacy of IAM1363 i…

HER2 Mutation-Related TumorsHER2HER2-positive Breast Cancer+10 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Iambic Therapeutics, IncNCT06253871

Inside Liposarcoma Clinical Trials: Patient Experiences Shared While Undergoing Clinical Trials

The study seeks to delve into the firsthand experiences of patients diagnosed with liposarcoma who partake in a separate clinical research featuring a specific…

Liposarcoma

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Power Life Sciences Inc.NCT06039046

Observational

A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

The hypothesis of this research protocol is that the investigators will be able to redesign the manner in which upper limb amputations are performed so as to e…

Amputation

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT03882073