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27,407 recruiting studies available now

ADEPT: Augmenting DBT Effectiveness With Psilocybin-Assisted Therapy

ADEPT is an open-label proof-of-concept study evaluating the safety and tolerability of psilocybin-assisted therapy in conjunction with Dialectical Behavior Th…

Borderline Personality DisorderBorderline Personality PathologyDepressive Symptoms+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of MinnesotaNCT07833761

Phase 2

Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery

The goal of this prospective pragmatic randomized clinical trial is to determine if preoperative administration of tranexamic acid (TXA) reduces bleeding durin…

BleedingColorectal DisordersThromboembolism+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Kristen BanNCT06657924

Phase 1

A Phase I/II, Randomized, Placebo-controlled, Multi-arm, Dose-finding Study to Evaluate the Safety, Efficacy and Immunogenicity of an Acne mRNA Vaccine Candidate in Adults With Moderate to Severe Acne 18 to 45 Years of Age

The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to…

Acne

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Sanofi Pasteur, a Sanofi CompanyNCT06316297

Observational

A Double-Blind, Randomized Study of Clinical Efficacy of Hypothermic Therapy Following Concussion in Adolescent Athletes as Compared to a Sham-Controlled Population

This study is being conducted to determine the clinical safety and efficacy of Pro-2-Cool mediated head and neck cooling when applied after concussion and impr…

Concussion, Mild

Estimated

~$10 – $1,050

Actual pay is set by the research site.

TecTraum Inc.NCT06929923

Observational

Measurement-based Care to Support Delivery of Buprenorphine-naloxone Treatment in Outpatient Addiction Clinics

People receiving buprenorphine-naloxone (bup-nx) for opioid use disorder often face changes in cravings, withdrawal, and return to use risk between clinic visi…

Opioid Use Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT07839182

Phase 2

Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related Dementias

This study is being done to research the usefulness of PET/CT imaging for measuring brain inflammation and its relation to Alzheimer's Disease Dementia and rel…

Lewy Body Dementia (LBD)Alzheimer Dementia (AD)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Val LoweNCT04786223

Phase 2

Pimavanserin for Insomnia in Veterans With Post-traumatic Stress Disorder

This is a preliminary randomized, double-blind, placebo-controlled trial comparing pimavanserin 34mg at bedtime vs. placebo for the treatment of insomnia assoc…

Post-traumatic Stress DisorderInsomnia

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT05441280

Phase 1

Phase 1 Dose Escalation and Expansion Study of PRAME T Cell Receptor (TCR) Engineered NK Cells in Participants With Recurrent and/or Refractory Melanoma (PRAMETIME-Mel)

To find the highest tolerable dose and recommended dose of PRAME-TCR-NK cells that can be given to participants with recurrent and/or refractory melanoma. The …

Phase 1Recurrent MelanomaRefractory Melanoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT06660420

Remote Monitoring in Progressive Supranuclear Palsy, an Alzheimer's Disease Related Dementia

This is a single-arm, longitudinal, observational study on the use of wearable sensors and digital health technology to measure fall frequency and motor, speec…

Progressive Supranuclear PalsyParkinson DiseaseMSA - Multiple System Atrophy

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT04753320

Phase 1

IIT2021-12-Reckamp-Osi105: Phase I Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

The purpose of this study is to examine the combination of osimertinib and carotuximab to assess the safety and find the recommended dose for treatment of adva…

Non Small Cell Lung CancerLung Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Karen Reckamp, MD, MSNCT05401110

Phase 2

A Phase 2 Trial of Leflunomide, Pomalidomide, and Dexamethasone for Relapsed/Refractory Multiple Myeloma

This phase II trial studies how well leflunomide, pomalidomide, and dexamethasone work for the treatment of multiple myeloma that has come back (relapsed) or d…

Recurrent Plasma Cell MyelomaRefractory Plasma Cell Myeloma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

City of Hope Medical CenterNCT04508790

Observational

Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge

This study aims to improve patient awareness of the utility of continuous glucose monitoring systems in blood glucose monitoring and to improve patient satisfa…

Type 2 Diabetes Mellitus (T2DM)Type 1 Diabetes Mellitus (T1DM)Hyperglycemia

Estimated

~$10 – $750

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT06852950