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27,384 recruiting studies available now

Trauma Recovery Via EEG and Actigraphy Tracking (TREAT): Biomarkers of Written Exposure Therapy in PTSD

Posttraumatic stress disorder, or PTSD, can affect emotional health, sleep, daily functioning, and quality of life. Written Exposure Therapy is a brief trauma-…

Posttraumatic Stress Disorder (PTSD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Mclean HospitalNCT07766798

Observational

Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation

We will recruit 10 patients with OCD meeting established criteria for surgical evaluation. Following informed consent and baseline evaluations, each will be im…

Obsessive Compulsive Disorder (OCD)Neuromodulation

Estimated

~$10 – $750

Actual pay is set by the research site.

Baylor College of MedicineNCT06596447

Phase 2

Randomized Phase 2 Clinical Trial of Repeated Intratumoral and Cervical Perilymphatic Lerapolturev Injections Versus Lomustine in Recurrent Glioblastoma (GBM)

The purpose of this research study is to determine the safety and efficacy of administering two doses of lerapolturev in residual disease (within tumor margins…

Recurrent Supratentorial Glioblastoma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Darell BignerNCT06177964

Phase 1

Phase I Dose Escalation and Cohort Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

The goal of this clinical trial is to learn if investigational drug called SYS6043 works in adults with advanced or metastatic solid tumors that have spread or…

CancerSolid Tumor CancerAdvanced Metastatic Cancer+4 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Conjupro Biotherapeutics, Inc.NCT07424547

Phase 3

A Randomized Phase III Study Comparing Temporally-Modulated Pulsed Radiation Therapy (TMPRT) Versus Standard Radiation Therapy With Temozolomide for Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma

This phase III trial compares temporally-modulated pulsed radiation therapy versus standard radiation therapy in treating patients with newly diagnosed, IDH wi…

Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

NRG OncologyNCT07452458

Phase 2

The Role of Inflammation in Central Nervous System (CNS) Mechanisms of Anhedonia and Psychomotor Slowing in Depressed People With HIV

The purpose of this 10-week, double-blind, placebo-controlled study is to determine whether inflammation impacts reward and motor neural circuitry to contribut…

HIVDepressionAnhedonia

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Emory UniversityNCT05849038

Phase 1

A Pilot Study Comparing Neoadjuvant and Adjuvant GVAX vs a Mutated KRAS Peptide Vaccine Given With Anti-PD-1 and Anti-CD137 for the Treatment of Surgically Resectable Pancreatic Adenocarcinoma

The purpose of this study is to determine the optimal dose of AGEN2373 that is safe when given in combination with balstilimab and Pancreatic GVAX Whole Cell V…

Pancreatic Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT06782932

Phase 1

A Phase I/II Study of Complement Inhibition in Pancreatic Ductal Adenocarcinoma

This phase I/II trial tests the effect of pegcetacoplan in combination with oxaliplatin, irinotecan, leucovorin, and fluorouracil (mFOLFIRINOX) in treating pat…

Metastatic Pancreatic Ductal AdenocarcinomaStage IV Pancreatic Cancer AJCC v8

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Roswell Park Cancer InstituteNCT07214298

Phase 2

Phase II Study of 18F-FFNP Breast PET/MRI in the Assessment of Early Response of Breast Cancer to Presurgical Endocrine Therapy

This clinical trial will investigate an estrogen-regulated parameter as an early measure of endocrine therapy response: progesterone receptor (PR) protein with…

Breast Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT06086704

Molecular and Behavioral Characterization of Post-Operative Sensory Outcomes in Individuals With Chronic Pain or Persistent Opioid Use

The incidence and severity of postoperative pain after spine surgery are notably high, often requiring intensive management and potentially affecting the patie…

Post Operative PainOpioid Use, Unspecified

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Medical CenterNCT06639438

A Prospective Cohort Study of Basivertebral Nerve Ablation Using the Stryker OptaBlate BVN System for the Treatment of Vertebrogenic Low Back Pain

The goal of this observational study is to evaluate patient outcomes following treatment of vertebrogenic low back pain using the Stryker OptaBlate BVN System.…

Verteborgenic Low Back PainBack Pain Lower Back

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Stryker InstrumentsNCT07392333

Observational

Video-Based AI-Generated Peri-operative Instructions for Mitral Valve Surgery: A Randomized Controlled Trial on Health Outcomes and Patient Experience

1. The purpose of this study is to evaluate the impact of a novel, AI-generated, interactive peri-operative video education program on total unplanned healthca…

Mitral Valve Repair Surgery

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Joanna ChikweNCT07036926