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27,384 recruiting studies available now

Androgen Replacement to Improve Patient-Important Outcomes in Men With Opioid-Induced Hypogonadism

The aim of this trial is to evaluate whether testosterone replacement results in greater improvement in pain perception, pain tolerance, sexual function, fatig…

Opioid UsePainHypogonadism, Male

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Brigham and Women's HospitalNCT04798469

Phase 4

Pioglitazone, Lipotoxicity, and Heart Failure With Preserved Ejection Fraction (HFpEF)

Our goal of the study is to learn the effects of the diabetes medication named Pioglitazone, in type-2 diabetic obese participants with Heart failure. The main…

Type 2 Diabetes Mellitus in ObeseHeart Failure With Preserved Ejection Fraction

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The University of Texas Health Science Center at San AntonioNCT05838287

Phase 4

A Prospective, Randomized, Double-blind Trial of the Impact of Intraoperative Intravenous Lidocaine Infusion on Total Opioid Requirements in Children Undergoing Surgical Fixation of Upper Extremity Long Bone Fractures Under General Anesthesia

This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid req…

Fracture ArmFracture Closed of Lower End of Forearm, UnspecifiedFracture Elbow+4 more

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Nemours Children's ClinicNCT07552766

Observational

Evaluating the Role of the Guidewire in Peripheral Intravenous Access: A Randomized Controlled Trial of Ultrasound-Guided Catheter Survival

This is a prospective, parallel, non-blinded, two-arm randomized controlled trial of intravenous catheter failure evaluating the impact of a built-in guide wir…

Peripheral Intravenous Vein Catheter PhlebitisIntravenous Infection

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Corewell Health EastNCT06107361

Observational

Development of Advanced Personalized Modular Pressure Relief Seating Cushion Systems: Testing and User Evaluation

30 Veterans who are full-time wheelchair users will use personalized modular cushions for two weeks each. Personalized cushions will be created using a cushion…

Mobility Impairment

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT03494127

Phase 1

Developing and Evaluating Collaboratively Designed Mindfulness and Identity-Affirming Practices for Unhoused LGBTQ Youth

In the present study, the investigators will conduct a pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy o…

Well-Being (Psychological Flourishing)Internalizing Mental Health SymptomsSubstance Abuse

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Cornell UniversityNCT07566273

Phase 3

Dronabinol and Epidiolex to Manage Uncontrolled Residual Symptoms of Buprenorphine Initiation Trial

The goal of this pilot study is to test novel, adjunctive pharmacotherapy for patients with opioid use disorder (POUD) who may be at risk for overdose and othe…

Opioid Use Disorder

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Montefiore Medical CenterNCT07148206

Observational

UnityPhilly Response App for Overdose Reversal: Assessing Citywide Effectiveness and Sustainability

The goal of this clinical trial is to discover if an overdose prevention app (UnityPhilly) can encourage citizen responders to respond and prevent opioid overd…

Opioid Overdose

Estimated

~$10 – $750

Actual pay is set by the research site.

Drexel UniversityNCT06466005

Cardiovascular and Cognitive Implications of Central Disorders of Hypersomnolence and Their Treatments

This is an observational study evaluating patients diagnosed with narcolepsy or idiopathic hypersomnia that have been prescribed a new/different hypersomnia tr…

NarcolepsyIdiopathic Hypersomnia

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT05371483

Phase 2

A Phase 2b, Randomized, Double Blind, Placebo Controlled, Parallel Group Trial to Assess the Efficacy and Safety of Obicetrapib in Participants With Preclinical Alzheimer's Disease (SPINOZA Trial)

A study evaluating Obicetrapib in adults potentially at risk for Preclinical Alzheimer's Disease

Preclinical Alzheimer's Disease

Estimated

~$75 – $2,800

Actual pay is set by the research site.

NewAmsterdam PharmaNCT07794670

Phase 4

The Influence of Estrogen on the Thermoregulatory Responses to Heat Stress in Pre and Postmenopausal Women

The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at …

MenopauseAging

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Penn State UniversityNCT06798571

Phase 1

A Phase 1b, Open-label, Multi-center, Randomized Study Evaluating the Safety and Tolerability of AZD0120, an Autologous CD19/BCMA Targeting Chimeric Antigen Receptor T-cells, in Adults With Refractory Relapsing or Progressive Multiple Sclerosis

This trial is a Phase 1b, open-label, multi-center, clinical study of AZD0120, a BCMA/CD19 dual targeting CAR+ T-cell therapy, to evaluate the safety and toler…

Multiple Sclerosis

Estimated

~$150 – $4,500

Actual pay is set by the research site.

AstraZenecaNCT07224373