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A Phase 3, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Participants With Isocitrate Dehydrogenase 1 (IDH1)-Mutant Glioma

This is a 3-part study. The purpose of Part 1 of the study is to evaluate the efficacy, safety, and pharmacokinetic (PK) characteristics of safusidenib in part…

GliomaAstrocytoma, Grade IVIDH1-mutant Glioma+5 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Nuvation Bio Inc.NCT05303519

Phase 2

The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People

The investigators recently demonstrated that blockade of Glucagon-Like Peptide-1's (GLP-1) receptor (GLP1R) results in changes in islet function without change…

Type 1 DiabetesType 2 Diabetes

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Mayo ClinicNCT06976619

ObservationalRemote eligible

Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer

Dyspnea, or breathlessness, is one of the most common and distressing symptoms experienced by patients with advanced lung cancer. The purpose of this multi-sit…

Advanced Lung CancerDyspnea

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT06791057

Phase 3

A Phase 3, Randomized, Double-blind, Study Evaluating Efficacy and Safety of Riliprubart Versus Intravenous Immunoglobulin (IVIg) in Participants With Chronic Inflammatory Demyelinating Polyneuropathy

The purpose of the study is to evaluate efficacy of riliprubart compared to IVIg in adult participants with CIDP who are receiving maintenance treatment with I…

Chronic Inflammatory Demyelinating Polyneuropathy

Estimated

~$50 – $2,250

Actual pay is set by the research site.

SanofiNCT06290141

Phase 3

Somatostatin Analogues vs. Observation After Peptide Receptor Radionuclide Therapy (PRRT) in Patients With Nonfunctional Neuroendocrine Neoplasms (REMAIN Trial)

This is a multicenter, randomized, open-label, phase III study comparing standard of care use of somatostatin analogues (SSAs) to standard of care observation …

Neuroendocrine NeoplasmGastroenteropancreatic Neuroendocrine Neoplasm

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Washington University School of MedicineNCT07842172

Phase 1

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Background: Alcohol use disorder (AUD) is a leading cause of disease and death worldwide. New treatments for AUD are needed. Dopamine, a chemical that carries…

Healthy VolunteersAlcohol Use Disorder (AUD)

Estimated

~$500 – $6,750

Actual pay is set by the research site.

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NCT06484075

CSP #595 - Pulmonary Health and Deployment to Southwest Asia and Afghanistan

The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Op…

Pulmonary Function

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT02825654

Phase 2

Phase 2/3, Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Subjects With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bone…

Multiple Myeloma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT07095452

Phase 3

A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin (a Conjugated Anti-CD22 Monoclonal Antibody) to Frontline Therapy in Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL

This phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with n…

B Acute Lymphoblastic Leukemia

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Alliance for Clinical Trials in OncologyNCT03150693

Observational

Review of Proximal Humerus Fracture Outcomes

Patients undergoing either operative or non-operative treatment of proximal humerus fractures will be studied with the goal of understanding which treatment mo…

Proximal Humerus Fracture

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Massachusetts, WorcesterNCT07060664

Observational

Harnessing Early Neuroplasticity in Infants With Perinatal Brain Injury: A Study of Combined Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) Paired With Constraint Induced Movement Therapy (CIMT) and Transcranial Magnetic Stimulation (TMS)

This study is for infants and toddlers between 8 and 24 months old who use one arm and/or hand differently following a perinatal brain injury. This is a time w…

Perinatal Brain Injury

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT07738432

Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy

Background: Down syndrome is a genetic disorder that can cause heart defects and other problems in the body. People with Down syndrome are more likely to have…

Down Syndrome

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT07416201