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A Phase 1 Double-blind (Sponsor-unblinded), Placebo-controlled, Randomized, Single Dose Escalation Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of VH4367310 Administered to Healthy Adult Participants

This study evaluates the PK, safety, and tolerability of a single increasing dose of VH4367310, a cabotegravir (CAB) prodrug, when administered intramuscularly…

HIV Infections

Estimated

~$500 – $11,250

Actual pay is set by the research site.

ViiV HealthcareNCT07818915

Observational

Stimulus-Evoked Directional Field Potentials to Guide Subthalamic and Pallidal DBS for PD

Our goal is to better understand how DBS modifies local neuronal activity and to pioneer device technologies that can record local DBS-evoked potentials (DLEPs…

Parkinson Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Alabama at BirminghamNCT06169852

Phase 2

Beamion PANTUMOR-1: A Phase II, Multicentre, Multicohort, Open-label Trial to Evaluate the Efficacy and Safety of Oral Zongertinib (BI 1810631) for the Treatment of Selected HER2-mutated or Overexpressed/Amplified Solid Tumours

This is a study for people with advanced cancer for whom previous treatment was not successful. Adults aged 18 and over with advanced cancer with HER2 alterati…

Solid Tumours

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Boehringer IngelheimNCT06581432

Observational

AGENT DCB STANCE: AGENT Drug-Coated Balloon for STent AvoidANCE in PCI for De Novo Coronary Artery Disease

AGENT DCB STANCE is a prospective, multicenter, open-label, 1:1 randomized controlled study designed to assess the safety and effectiveness of a treatment stra…

Coronary Arterial Disease (CAD)de Novo Lesions in Native Coronary Arteries

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Boston Scientific CorporationNCT06959524

Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for the Treatment of Polycystic Ovary Syndrome

This trial will study the safety and efficacy of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells delivered intravenously f…

Polycystic Ovary Syndrome (PCOS)Polycystic Ovary SyndromePCOS

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT06143527

Observational

Comparing Group Behavioral Interventions to Improve Dementia Caregiver Strain

The goal of this clinical trial is to compare two group-based interventions for caregivers of persons with memory loss (N=450) delivered via telehealth. The ai…

Elevated Caregiver StrainDementia CaregiverCaregiver Stress

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT07868588

Phase 2

A Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2/3 Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer (TeLuRide-008).

This is a study to evaluate the safety and efficacy of EIK1001 administered intravenously in combination with pembrolizumab and histologically appropriate chem…

Non Small Cell Lung Cancer (Squamous or Non Squamous)Stage 4 NSCLC

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Eikon TherapeuticsNCT07365319

Observational

Phase IIa Clinical Trial of External Trigeminal Nerve Stimulation for Autistic Children With Attention Deficit/Hyperactivity Disorder

The goal of this clinical trial is to learn if external trigeminal nerve stimulation (eTNS) works to treat ADHD symptoms in children on the autism spectrum (AS…

Attention Deficit Disorder With Hyperactivity (ADHD)Autism Spectrum Disorder (ASD)

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT07214545

Phase 1

A Phase 1a/b Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of PRMT5 Inhibitor BGB-58067 Alone and in Combination With Anticancer Agents in Patients With Advanced Solid Tumors

This is an open-label, multicenter, first-in-human dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, pharmacodyn…

Advanced Solid Tumor

Estimated

~$150 – $4,500

Actual pay is set by the research site.

BeOne MedicinesNCT06589596

Observational

Virtual Reality Implementation for Pain and Anxiety Management During Intra-articular Glucocorticoid Injections in a Pediatric Rheumatology Clinic

The goal of the project is to implement virtual reality for pain and anxiety management for patients undergoing intra-articular glucocorticoid injections in th…

Acute PainProcedural AnxietyJuvenile Idiopahtic Arthritis

Estimated

~$10 – $750

Actual pay is set by the research site.

Nationwide Children's HospitalNCT07778069

Phase 3

Phase 3 Study of the Efficacy and Safety of ION582 in Children and Adults With Angelman Syndrome Due to Paternal Uniparental Disomy or Imprinting Defects

The primary purpose of the study is to evaluate efficacy of obudanersen in participants with AS due to uniparental disomy or imprinting defects (UPD/ID) as mea…

Angelman Syndrome

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Ionis Pharmaceuticals, Inc.NCT07782827

Phase 3

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized Adults With COVID-19 at High Risk for Disease Progression

Researchers are looking for other ways to prevent severe illness from COVID-19. COVID-19 is a virus that most often causes mild flu or cold-like symptoms. Howe…

Coronavirus Disease (COVID-19)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT06667700