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27,270 recruiting studies available now

Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce CVD events, including incident HF. SGLT2 is a glucose transport protein in the kidneys. Inhibition of…

HypertensionCardiovascular Diseases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of MinnesotaNCT06507657

Observational

Improving Academic and Social Functioning in Middle-Schoolers With Autism

The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD). One of the intervention…

AutismAutism Spectrum Disorder

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT06705907

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

The purpose of this protocol is to create a repository of blood samples from patients diagnosed with primary and metastatic brain tumors who are being seen in …

Brain Tumor, PrimaryBrain Metastases, Adult

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT05480644

Phase 1

Activating Neuroplasticity to ENHANCE the Perception Box Expanding Effects of Psilocybin

This study will examine whether combining a single dose of psilocybin with non-invasive transcutaneous auricular vagus nerve stimulation (taVNS), a potential i…

HealthyPsychedelic ExperiencesVagus Nerve Stimulation

Estimated

~$500 – $7,500

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT05866471

Phase 2

A Phase II Randomized Controlled Trial Comparing GVHD-Reduction Strategies for Allogeneic Peripheral Blood Transplantation (PBSCT) for Patients With Acute Leukemia or Myelodysplastic Syndrome: Selective Depletion of CD45RA+ Naïve T Cells (TND) vs. Post-Transplantation Cyclophosphamide (PTCy)

This phase II trial investigates two strategies and how well they work for the reduction of graft versus host disease in patients with acute leukemia or MDS in…

Acute LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+2 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Fred Hutchinson Cancer CenterNCT03970096

Observational

Neural and Psychological Mechanisms of Pain Perception

Background: \- Painful stimuli cause changes in a network of brain regions called the "Pain Matrix." But most of these regions respond to many other stimuli, …

PainNormal PhysiologyHealthy Volunteers

Estimated

~$10 – $1,125

Actual pay is set by the research site.

National Center for Complementary and Integrative Health (NCCIH)NCT02446262

Phase 4

Hypertonic Saline for Treatment of Pulmonary Mycobacterium Avium Complex (MAC) Disease

The MAC-HS study is a testing whether hypertonic saline helps improve symptoms and clearance of mycobacteria in patients with M. avium complex lung infections.

Nontuberculous Mycobacterial Lung DiseaseNontuberculous Mycobacterium Infection

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Oregon Health and Science UniversityNCT04921943

Phase 1

A Phase 1/2, Study to Evaluate the Safety, Tolerability, and Efficacy of One-time Intravitreal Dose of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

This is a sequential Phase 1/2, two-part, multicenter study on safety, tolerability, and efficacy of one-time intravitreal SAR446597 for the treatment of parti…

Geographic Atrophy

Estimated

~$150 – $4,500

Actual pay is set by the research site.

SanofiNCT07215234

Phase 1

Soy Tomato Juice to Improve Outcomes in Pancreatitis (the STOP Trial): a Phase 1/2 Single Arm Trial

This goal of this clinical trial is to see if people with recurrent acute pancreatitis or chronic pancreatitis can tolerate and regularly drink a tomato juice …

Recurrent Acute PancreatitisChronic Pancreatitis

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Ohio State UniversityNCT07447687

Phase 2

PROACT AYA: Preventing Overweight/Obesity-Associated Cardiotoxicity With Tirzepatide In Adolescent And Young Adult Cancer Survivors - A Phase 2 Single-Arm, Single-Center Feasibility Study

This is a prospective, single-arm, open-label feasibility trial conducted at the MD Anderson Sarcoma Center and Cardio-Oncology Clinic. The study will enroll y…

Sarcoma,Soft Tissue

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT07874828

Phase 2

Cardioprotective Effects of Empagliflozin in Breast Cancer Patients Receiving Chemotherapy: A Pilot Study

The primary objective of this pilot study is to evaluate the feasibility and acceptability of a clinical trial protocol investigating 10 mg/day empagliflozin i…

Breast CancerSupportive Care in Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Virginia Commonwealth UniversityNCT07883512

Phase 2

A Randomized, Double-blind, Placebo-controlled Study Investigating the Effect of ALN-4324 on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus

The purpose of this study is to evaluate the effect of a single dose of ALN-4324 on whole-body insulin sensitivity in participants with T2DM

Type 2 Diabetes Mellitus (T2DM)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Alnylam PharmaceuticalsNCT07465224