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27,270 recruiting studies available now

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, inpatient study in participants with bipolar disorder experiencing an acute episo…

Bipolar Disorder Type I With Mania or Mania With Mixed Features

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Bristol-Myers SquibbNCT06951711

Observational

Effectiveness of Various Exercises in Managing Kyphosis

The primary objective of this study is to determine if stretching exercises as a conservative treatment option will correct kyphosis in postural and Scheuerman…

Kyphosis

Estimated

~$10 – $750

Actual pay is set by the research site.

Cedars-Sinai Medical CenterNCT06082739

Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections From Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation

Bone marrow transplants (BMT) are one form of treatment for disorders of the blood, including leukemia. However, because the procedure is often associated with…

Graft-Versus-Host DiseaseGraft-versus-leukemiaDonor Apheresis

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT00001529

Real-world Clinical Outcomes in Medicare Patients With Hypertension Treated With Symplicity Renal Denervation Plus Standard of Care Versus Standard of Care in Integrated EHR and Claims Data

This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypert…

HypertensionCardiovascular DiseasesVascular Diseases

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medtronic VascularNCT07174622

Phase 1

A Phase 1, Randomized, Participant- and Investigator-Blinded, Placebo-Controlled, Parallel-Design Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Dose Regimens of LY4167586 in Participants With Obesity or Overweight With or Without Type 2 Diabetes

The main purpose of this study is to look at how safe and well-tolerated LY4167586 is in participants with obesity or overweight with or without Type 2 Diabete…

ObesityOverweightDiabetes Mellitus, Type 2

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Eli Lilly and CompanyNCT07881887

Phase 1

A Phase 1/2 Study to Evaluate the Safety and Efficacy of MK-2870 Monotherapy or in Combination With Other Anticancer Agents in Gastrointestinal Cancers

Researchers want to learn if sacituzumab tirumotecan (MK-2870) alone or with other treatments can treat certain gastrointestinal (GI) cancers. The GI cancers b…

Colorectal CancerPancreatic Ductal AdenocarcinomaBiliary Tract Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT06428409

Observational

Do Dietary Patterns Influence Your Weight Management and Circadian Rhythms?

The goal of this clinical trial is to test the effects of dietary composition on the rhythms of food intake, appetite regulation, and rhythms of energy expendi…

Dietary Intervention

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT05800990

Phase 3

A Randomized, Phase 3, Double-blind, 52-week Study to Evaluate the Efficacy and Safety of Rilzabrutinib (SAR444671) Compared to Placebo in Adult Participants With Active IgG4-related Disease

This is a Phase 3, parallel group, 2-arm, randomized, double blind, placebo-controlled, 52-week treatment study to assess the efficacy and safety of rilzabruti…

Immunoglobulin G4 Related Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

SanofiNCT07190196

Phase 4

Modulation of PSMA Expression in Castration Sensitive and Castration Resistant Prostate Cancer in Response to Hormonal Therapy

This clinical trial investigates the change in prostate-specific membrane antigen (PSMA) expression in response to hormonal therapy in both, Castration Sensiti…

Castration Resistant Prostate CancerCastration Sensitive Prostate CancerProstate Adenocarcinoma

Estimated

~$25 – $1,500

Actual pay is set by the research site.

OHSU Knight Cancer InstituteNCT05919329

Phase 1

A Platform Study of RAS(ON) Inhibitors in Patients With RAS-Mutated Non-Small Cell Lung Cancer (NSCLC)

The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibito…

Non-Small Cell Lung Cancer, NSCLCKRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Revolution Medicines, Inc.NCT06162221

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

Objectives: The overall study objective is to compare the sensitivities and specificities of morphometric analysis techniques using structural MRI images base…

Epilepsy

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Neurological Disorders and Stroke (NINDS)NCT02107989

Phase 2

A Phase 2, Open-Label, Randomized, Master Protocol Study to Evaluate Safety and Efficacy of Multiple Treatment Combinations With Telisotuzumab Adizutecan in Subjects With Metastatic Colorectal Cancer

CRC is the third most common type of cancer diagnosed worldwide with developed countries at highest risk. The purpose of this study is to assess adverse events…

Metastatic Colorectal Cancer

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT06820463