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A Multi-gene Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: Open-label, Mayo Clinic Multisite (Mayo Clinic Health System-Rochester Primary Care), Controlled, Implementation Study Taking the Results of the PREPARE Study Into Minnesota (PREPARE-Mayo)

The purpose of this study is to determine whether the implementation of pre-emptive pharmacogenomic (PGx) testing of a panel of clinically relevant PGx markers…

Pharmacogenomic Drug InteractionSide Effect of DrugIneffective Drug Action+2 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Mayo ClinicNCT06322238

Phase 3

An Interventional Efficacy and Safety Phase 3 Double-blind 2-arm Study to Investigate IV Followed by Oral Fosmanogepix Compared With IV Caspofungin Followed by Oral Fluconazole in Adult Participants With Candidemia and/or Invasive Candidiasis

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Fosmanogepix) for the potential treatment of candidem…

CandidemiaCandidiasis, Invasive

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Basilea PharmaceuticaNCT05421858

Phase 1

Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet

Ketogenic diet therapies (KDTs) emphasize high fat and very low carbohydrate intake and help to control seizures in adults who fail to respond to medications. …

EpilepsyDyslipidemia

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Johns Hopkins UniversityNCT06369571

Observational

Boosting Exercise Adherence in Knee Osteoarthritis (BOOST-OA)

This project, conducted within the Department of Veterans Affairs Healthcare System (VHA), will test the effectiveness of an intervention to improve adherence …

Osteoarthritis, Knee

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07219732

Phase 4

Differentiating the Effects of Long-acting Bronchodilators Administered by Nebulizer Versus Dry Powder Inhaler in Symptomatic Patients With Chronic Obstructive Pulmonary Disease

The purpose of this study is to compare the effectiveness of inhaled bronchodilators delivered via nebulizers vs. dry powder inhalers (DPIs) in symptomatic par…

COPD (Chronic Obstructive Pulmonary Disease)

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of Tennessee Graduate School of MedicineNCT07133880

Phase 3

Randomized Phase III Trial INcorporating Pathologic Complete ReSponse in Participants With Early StaGe Non Small Cell Lung Cancer to Optimize ImmunotHerapy in The AdjuvanT Setting (INSIGHT)

This phase III trial compares durvalumab to the usual approach (patient observation) after surgery for the treatment of patients with early-stage non-small cel…

Lung Non-Small Cell CarcinomaStage II Lung Cancer AJCC v8Stage IIIA Lung Cancer AJCC v8+1 more

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06498635

Phase 4

Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery

This is a randomized controlled trial employing a Sequential Multiple Assignment Randomized Trial (SMART) design to test whether pharmacotherapy, in conjunctio…

Obesity

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of California, IrvineNCT05975580

Observational

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

The purpose of this study is to evaluate the efficacy of an adaptive web intervention (Partners Connect) on military spouse drinking behaviors (CPs) and servic…

Alcohol AbuseAlcohol Use DisorderAlcohol Drinking+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT05619185

Phase 1

Chorionic Gonadotropin to Improve Rehabilitation After Brain Injury - The COGNI-REHAB Study

The COGNI-REHAB Trial is a single-site, phase O/I, randomized, double-blind, placebo-controlled study of human chorionic gonadotropin (hCG; choriogonadotropin …

Traumatic Brain Injury

Estimated

~$150 – $2,700

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07557615

Observational

A Pragmatic, Single-blind, Randomized Crossover Trial Testing the Effectiveness of Autonomous Remote Patient Peripheral Edema Monitoring and Reporting in HEART FailurE Compared to conventionaL remoTe Patient Monitoring.

This pragmatic randomized crossover trial looks at the effect(s) of using a remote patient monitoring device (Heartfelt device) with health alerts to monitor t…

Heart FailureChronic Heart Failure

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Heartfelt TechnologiesNCT06222099

Phase 1

A Phase II Trial of MOR Antagonism With Axelopran and Nivolumab in PD-1-Refractory Metastatic Melanoma (MORALE-MM)

This first-in-human study will evaluate the safety, clinical activity, and immunologic effects of combining axelopran with nivolumab in patients with PD-1-refr…

Unresectable Cutaneous Melanoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

John KirkwoodNCT07631325

Phase 1

A Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Misetionamide (GP-2250) as Monotherapy or in Combination With Gemcitabine in Subjects With Advanced Solid Tumors

This is a phase 1 dose escalation trial of monotherapy misetionamide (also known as GP-2250) currently enrolling patients with platinum-resistant ovarian cance…

Ovarian Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Persevere Therapeutics Inc.NCT03854110