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27,292 recruiting studies available now

Real-world Clinical Outcomes in Medicare Patients With Hypertension Treated With Symplicity Renal Denervation Plus Standard of Care Versus Standard of Care in Integrated EHR and Claims Data

This observational study will assess the long-term effectiveness of the RDN procedure for lowering blood pressure in Medicare patients with uncontrolled hypert…

HypertensionCardiovascular DiseasesVascular Diseases

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medtronic VascularNCT07174622

Phase 1

A Phase 1, Randomized, Participant- and Investigator-Blinded, Placebo-Controlled, Parallel-Design Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Dose Regimens of LY4167586 in Participants With Obesity or Overweight With or Without Type 2 Diabetes

The main purpose of this study is to look at how safe and well-tolerated LY4167586 is in participants with obesity or overweight with or without Type 2 Diabete…

ObesityOverweightDiabetes Mellitus, Type 2

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Eli Lilly and CompanyNCT07881887

Phase 1

A Phase 1/2 Study to Evaluate the Safety and Efficacy of MK-2870 Monotherapy or in Combination With Other Anticancer Agents in Gastrointestinal Cancers

Researchers want to learn if sacituzumab tirumotecan (MK-2870) alone or with other treatments can treat certain gastrointestinal (GI) cancers. The GI cancers b…

Colorectal CancerPancreatic Ductal AdenocarcinomaBiliary Tract Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT06428409

Observational

Do Dietary Patterns Influence Your Weight Management and Circadian Rhythms?

The goal of this clinical trial is to test the effects of dietary composition on the rhythms of food intake, appetite regulation, and rhythms of energy expendi…

Dietary Intervention

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT05800990

Phase 3

A Randomized, Phase 3, Double-blind, 52-week Study to Evaluate the Efficacy and Safety of Rilzabrutinib (SAR444671) Compared to Placebo in Adult Participants With Active IgG4-related Disease

This is a Phase 3, parallel group, 2-arm, randomized, double blind, placebo-controlled, 52-week treatment study to assess the efficacy and safety of rilzabruti…

Immunoglobulin G4 Related Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

SanofiNCT07190196

Phase 4

Modulation of PSMA Expression in Castration Sensitive and Castration Resistant Prostate Cancer in Response to Hormonal Therapy

This clinical trial investigates the change in prostate-specific membrane antigen (PSMA) expression in response to hormonal therapy in both, Castration Sensiti…

Castration Resistant Prostate CancerCastration Sensitive Prostate CancerProstate Adenocarcinoma

Estimated

~$25 – $1,500

Actual pay is set by the research site.

OHSU Knight Cancer InstituteNCT05919329

Phase 1

A Platform Study of RAS(ON) Inhibitors in Patients With RAS-Mutated Non-Small Cell Lung Cancer (NSCLC)

The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibito…

Non-Small Cell Lung Cancer, NSCLCKRAS, NRAS, HRAS-mutated NSCLCKRAS G12C-mutated Solid Tumors, Lung Cancer+2 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Revolution Medicines, Inc.NCT06162221

Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

Objectives: The overall study objective is to compare the sensitivities and specificities of morphometric analysis techniques using structural MRI images base…

Epilepsy

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Neurological Disorders and Stroke (NINDS)NCT02107989

Observational

Enhancing the Organizational Social Context to Improve Viral Suppression and Retention in HIV Care: A Randomized Controlled Trial

Despite the widespread use of effective antiretroviral therapy (ART), the HIV epidemic continues to impact racial and ethnic minority populations disproportion…

HIV/AIDS

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PennsylvaniaNCT06462807

Observational

Transcranial Stimulation Combined With Auditory Training

The goal of this clinical trial is to learn if non-invasive brain stimulation (called transcranial stimulation) can enhance the benefits from auditory training…

Difficulties Understanding Speech in Noise

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston University Charles River CampusNCT06738030

Phase 2

A Randomized Trial of Neratinib, A Pan-ERBB Inhibitor, Alone or in Combination With Palbociclib, a CDK4/6 Inhibitor, in Patients With HER2+ Gynecologic Cancers and Other Solid Tumors: A ComboMATCH Treatment Trial

This phase II ComboMATCH treatment trial compares the effect of neratinib to the combination of neratinib and palbociclib in treating patients with HER2 positi…

Malignant Female Reproductive System NeoplasmMalignant Solid NeoplasmRecurrent Malignant Female Reproductive System Neoplasm+1 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06126276

Phase 1

Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2

An exploratory, randomized, double-blinded, placebo-controlled, two-center clinical trial to determine the maximum tolerated dosage of intravenous tirofiban in…

Aneurysmal Subarachnoid Hemorrhage

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Dr David Hasan, M.D.NCT07493577