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27,292 recruiting studies available now

A Phase 2 Trial of Systemic Administration of Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Patients Undergoing Thyroidectomy

Bevonescein (ALM-488) is a novel fluorescein-containing peptide that is intended as a visualization adjunct for the real-time enhanced structural delineation o…

Head and Neck DisorderHead and Neck Cancer

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Matthew SpectorNCT07631650

Phase 1

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Protocol # 000860 Background: Diffuse gliomas are tumors that affect the brain and spinal cord. Gliomas that develop in people with certain gene mutations (I…

Brain TumorCancer

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05588141

Sleep and Adolescent Vaccine Immunogenicity (SAVI) Pilot Study

This study tests whether the sleep habits of 11-12 years-olds impact their response to a vaccine that protects against meningococcal illness. That vaccine is t…

Vaccination

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT07636525

Phase 2

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Background: Throat cancer is a common tumor that can occur in people infected with the human papilloma virus (HPV). Most people with this cancer survive more …

Squamous Cell Carcinoma of the Head and NeckOropharynxHuman Papillomavirus Viruses+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06223568

Phase 3

A Phase 2b/Phase 3, Randomized, Double-blind, Placebocontrolled, Multicenter Study, to Investigate the Efficacy and Safety of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared…

Chronic Obstructive Pulmonary Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

SanofiNCT07190209

Observational

Using Nicotine to Reverse Age-related Auditory Processing Deficits: Human Psychophysics and Electrophysiology

The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered…

Auditory Perceptual ImpairmentAging

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, IrvineNCT04971954

Phase 1

An Open-label, Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 Following Single-ascending Dose and Step-up Dose Administration to Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis

The purpose of this study is to measure the safety, tolerability, PK, and PD of AZD5492 administered subcutaneously in adult participants with SLE or IIM or RA…

Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesRheumatoid Arthritis

Estimated

~$150 – $4,500

Actual pay is set by the research site.

AstraZenecaNCT06916806

Intraoperative OCT Guidance of Intraocular Surger

The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging d…

Macular HolesEpiretinal MembraneDiabetic Retinopathy+7 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT03713268

Phase 1

An Open-Label, Single-Arm, Phase 1/2 Dose-Escalation Trial of Long-Acting Recombinant Human IL-7 (NT-I7, Efineptakin-Alpha) for Idiopathic CD4 Lymphopenia

Background: Idiopathic CD4 lymphopenia (ICL) is a syndrome characterized by low levels of certain immune cells called CD4 T cells. The low CD4 T cells renders…

Idiopathic CD4 Lymphopenia

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT05600920

Observational

A Novel Attachment Design for Tooth Rotation With Clear Aligner Therapy

Clear aligners are thin, transparent plastic trays that straighten teeth gradually and are a popular, more discreet alternative to traditional braces. To help …

Rotation of Tooth

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston UniversityNCT07881146

Observational

GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Wellness in Adults, Wave 1

The goal of this study is to evaluate the effects of different products in participants experiencing feelings of anxiety. The main question it aims to answer i…

Sleep DisturbanceStressFeeling Anxious

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Holobiome, Inc.NCT07752823

Phase 3

A Phase 3 Open-Label, Randomized, Controlled, Global Study of Telisotuzumab Vedotin (ABBV-399) Versus Docetaxel in Subjects With Previously Treated c-Met Overexpressing, EGFR Wildtype, Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-small cell lung cancer (NSCLC) is a solid tumor, a disease …

Non Small Cell Lung Cancerc-MET

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AbbVieNCT04928846