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27,273 recruiting studies available now

Pericardiotomy in Cardiac Surgery Trial

PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or f…

Atrial FibrillationAtrial FlutterCardiac Events

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Population Health Research InstituteNCT06486636

Observational

Transcranial Stimulation Combined With Auditory Training

The goal of this clinical trial is to learn if non-invasive brain stimulation (called transcranial stimulation) can enhance the benefits from auditory training…

Difficulties Understanding Speech in Noise

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston University Charles River CampusNCT06738030

Observational

Preventing Loss of Independence Through Exercise in Community Living Centers: An Effectiveness-Implementation Trial

Approximately 40,000 older Veterans with complex care needs receive long-term care in VA Community Living Centers (CLCs). Many CLC staff have limited specializ…

DementiaCognitive Dysfunction

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT06972004

Phase 1

Open-label, Non-randomized, Multi-cohort, Phase 1b/2 Trial Investigating the Safety, Tolerability, and Antitumor Activity of STC-15 (a METTL3 Inhibitor) as a Part of Combination Therapy With Toripalimab in Participants With Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

This early phase oncology trial will be conducted at various study centers to investigate the safety, tolerability, and antitumor activity of STC-15 (a METTL3 …

Solid TumorSarcomaLeiomyosarcoma+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

STORM Therapeutics LTDNCT06975293

Phase 3

A Pivotal Open-label Phase 3 Clinical Study Evaluating the Efficacy and Safety of QTX-2101 in Combination With All-trans Retinoic Acid in Newly Diagnosed, Low-risk Acute Promyelocytic Leukemia

This Phase 3 study in adult participants with newly diagnosed low-risk APL will evaluate the efficacy, safety, and PK of an oral capsule formulation of ATO, in…

Acute Promyelocytic Leukemia (APL)Acute Promyelocytic LeukaemiaAcute Promyelocytic Leukemia With PML-RARA+2 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Quetzal TherapeuticsNCT07504458

Phase 1

Effect of Cannabis Use on Synaptic Density in Older Adults

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using \[11C\]UCB-J PET imaging.

Cannabis Use

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Yale UniversityNCT05465538

Phase 2

Phase 2 Randomized, Double-blind, Placebo-Controlled Trial Assessing the Efficacy and Safety of Icovamenib in Participants With Type 2 Diabetes Not Achieving Glycemic Targets Despite GLP-1-Based Therapy

This is a phase 2 randomized, double-blind, placebo-controlled trial assessing the efficacy and safety of icovamenib in participants with Type 2 Diabetes (T2D)…

Type 2 Diabetes

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Biomea Fusion Inc.NCT07502508

Phase 2

A Randomized Trial of Neratinib, A Pan-ERBB Inhibitor, Alone or in Combination With Palbociclib, a CDK4/6 Inhibitor, in Patients With HER2+ Gynecologic Cancers and Other Solid Tumors: A ComboMATCH Treatment Trial

This phase II ComboMATCH treatment trial compares the effect of neratinib to the combination of neratinib and palbociclib in treating patients with HER2 positi…

Malignant Female Reproductive System NeoplasmMalignant Solid NeoplasmRecurrent Malignant Female Reproductive System Neoplasm+1 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06126276

Phase 1

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for the Treatment of Crohn's Disease or Ulcerative Colitis

This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells f…

Inflammatory Bowel Diseases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT05003947

Observational

Adapting Exposure Therapy to Target Anxiety About Weight Gain in Adolescents With Anorexia Nervosa

This pilot study is evaluating Exposure Therapy (Exp-AN) as a virtual treatment for adolescents (ages 14 - 17 years) with anorexia nervosa (AN) recruited from …

Anorexia Nervosa

Estimated

~$10 – $750

Actual pay is set by the research site.

Milton S. Hershey Medical CenterNCT07188155

Phase 1

LIGHTBEAM-U01 Substudy 01D: A Phase 1b/2 Substudy to Evaluate the Safety and Efficacy of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors

Researchers are looking for new ways to treat children with relapsed or refractory solid tumors: * Relapsed means the cancer came back after treatment * Refra…

Malignant Neoplasm

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07630974

The FLOW Registry: Functional and Longitudinal Outcomes With Waterjet Ablation

The purpose of this study is to create a database and prospective registry for data collection on patients with benign prostatic hyperplasia undergoing Aquabla…

Benign Prostatic Hyperplasia (BPH)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ChicagoNCT07430423