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From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects

This is a multicenter prospective study of patients who currently have stably implanted spinal cord simulators. Patients will be randomly assigned to turn on o…

Chronic Pain

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT05661903

Phase 2

Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

The long-term goal is to test the clinical efficacy of senolytic therapies to reduce progression to and severity of sepsis in older patients. The central hypot…

SepsisAcute InfectionOrgan Failure

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of MinnesotaNCT05758246

Phase 1

Bilateral Orthotopic Lung Transplant in Tandem With CD3+ and CD19+ Cell Depleted Bone Marrow Transplant From Partially HLA-Matched Cadaveric Donors

The purpose of this study is to determine whether bilateral orthotopic lung transplantation (BOLT) followed by cadaveric partially-matched hematopoietic stem c…

Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Paul Szabolcs

Analysis of Human ALS Tissues and Registry of ALS Patients

Amyotrophic Lateral Sclerosis (ALS), often referred to as Lou Gehrig's Disease, is a progressive, terminal condition of muscle weakness that is associated with…

Amyotrophic Lateral Sclerosis

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Illinois at ChicagoNCT05067179

Observational

Using Real Time Mobile Health Approaches to Understand and Promote Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherenc…

Acute Lymphoblastic LeukemiaLymphoblastic Lymphoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT03932903

Phase 2

CORTISHOCK-P: A Randomized Pilot Trial of Corticosteroids as a Pharmacologic Adjunct to Temporary Mechanical Circulatory Support in Inflammation-Enriched Heart Failure Cardiogenic Shock

This pilot study investigates whether giving a short course of intravenous corticosteroids (methylprednisolone) alongside standard medical care can help patien…

Cardiogenic ShockHeart FailureInflammation

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Brigham and Women's HospitalNCT07461961

Phase 3

A Phase III Open-Label, Multicenter, Randomized, Controlled Clinical Trial to Evaluate the Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Mixed-Depth, Full-Thickness Burn Wounds as an Alternative to Autografting

To evaluate the safety and efficacy of realSKIN® to provide complete wound closure of mixed-depth, full-thickness burn wounds as an alternative treatment to au…

Burns Degree ThirdBurn (Disorder)Burn Degree Second+2 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

XenoTherapeutics, Inc.NCT06223269

Observational

Enhancing Parkinson's Disease Rehabilitation Through Remote Haptic Guidance: Field Study

Individuals with Parkinson's Disease (PD) often have motor difficulties that can negatively impact daily activities and their quality of life. Research has sho…

Parkinson's Disease (PD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Virginia Polytechnic Institute and State UniversityNCT07457710

Phase 1

A Phase 1, Randomized, Placebo-Controlled, First-in-Human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Orally Administered KT-579 in Healthy Adult Participants

This is a first-in-human study to evaluate safety and tolerability, pharmacokinetics, and pharmacodynamics of single and multiple dose levels of KT-579 in heal…

Healthy Participants

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Kymera Therapeutics, Inc.NCT07412288

Phase 2

IIT2022-05-Sankar-BELIEVE: Phase II Study of Bevacizumab in Combination With Chemoimmunotherapy and Maintenance Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

This clinical trial aims to assess whether the addition of bevacizumab to atezolizumab and chemotherapy can improve response to treatment and progression-free …

Extensive-stage Small-cell Lung CancerLiver Metastases

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Kamya SankarNCT05588388

Phase 1

A Phase 1 Study to Assess Safety and Tolerability of REGN5837, an Anti-CD22 x Anti-CD28 Costimulatory Bispecific Monoclonal Antibody, in Combination With Odronextamab, an Anti-CD20 x Anti-CD3 Bispecific Monoclonal Antibody, in Patients With Aggressive B-Cell Non-Hodgkin Lymphomas (ATHENA-1)

This study is researching an experimental drug called REGN5837 in combination with another drug, odronextamab (called "study drug\[s\]"), in patients with rela…

B-cell Non-Hodgkins Lymphoma (B-NHL)

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Regeneron PharmaceuticalsNCT05685173

Phase 1

A Phase 1, Multi-center, Single-dose, Open-label Study to Evaluate the Pharmacokinetics and Safety of Golcadomide (BMS-986369) in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function

The purpose of this study is to assess the pharmacokinetics and safety of golcadomide (BMS-986369) in matched healthy participants with normal renal function, …

Kidney Failure, Chronic

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Bristol-Myers SquibbNCT07763418