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27,288 recruiting studies available now

Ginger and the Microbiota-gut-brain Connection in Sciatic Pain Individuals

Neuropathic pain affects the quality of life of many Americans. Non-pharmacological strategies such as bioactive compounds in foods are being explored as thera…

Neuropathic PainSciatic Pain

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Leslie ShenNCT06817018

Phase 1

[C-11]NPA PET-amphetamine in Cocaine Use Disorders (Aim 2)

This study uses \[11C\]NPA positron emission tomography (PET) and a d-amphetamine challenge to image amphetamine induced dopamine release in the striatum in su…

Cocaine Use Disorder

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Rajesh NarendranNCT05011760

Phase 1

Dexmedetomidine Trial for Effects on Rhythms, Sleep Architecture, and Biomarker Dynamics - A Pilot Study (DEXTER)

The DEXTER study is a cross-over, double-blind, placebo-controlled pilot research study led by Dr. Peng Li. The goal of this project is to evaluate the safety,…

SleepCircadian Rhythm

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Massachusetts General HospitalNCT07800910

Observational

Comparative Effectiveness of Primary Care Providers Trained in Rheumatoid Arthritis Management Versus Rheumatologist Care: A Randomized Controlled Trial

Rheumatoid arthritis (RA) is a complex autoimmune disease where the immune system attacks healthy joint tissue; causing pain, swelling, and stiffness of the jo…

Rheumatoid Arthritis (RA

Estimated

~$10 – $750

Actual pay is set by the research site.

St. Lawrence Health SystemNCT07034196

Phase 1

Exploring the Impact of Montelukast, SPM, and/or Almond/Almond Oil Supplementation on Lipid Mediator Biosynthesis in Colorectal, Sarcomas, Brain Tumors, Endometrial, and Ovarian Cancer: A Pilot Study

The purpose of this study is to create a prospective investigation to examine the effects of montelukast, almonds/almond oil, and specialized pro-resolving med…

Colorectal CancerSarcomaBrain Tumors+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of South FloridaNCT06887673

Observational

Effects of Acute Ketone Supplementation on the Brain [KETO-BRAIN]

The purpose of this study is to determine how a ketone ester supplement affects brain function, brain blood flow, and brain metabolism in healthy middle-aged a…

Brain Health

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Christopher CrabtreeNCT07711990

Phase 1

A Phase 1 Study of the Antibody-Radionuclide Conjugate SLR-108 for Positron Emission Tomography Imaging in Subjects With Metastatic Solid Tumors

This is a Phase 1 study evaluating the feasibility of using SLR-108 for positron-emission tomography (PET) imaging of metastatic solid tumors.

Metastatic Solid Tumors

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Solve TherapeuticsNCT07728942

Phase 4

A Multicentre, Open-label, Randomised Phase IV Study to Investigate Acalabrutinib Monotherapy Compared to Investigator's Choice of Treatment in Adults (> 18 Years) With Chronic Lymphocytic Leukaemia and Moderate to Severe Cardiac Impairment

This will be a global Phase IV, open-label, randomised study to evaluate the safety and tolerability of acalabrutinib (monotherapy, 100 mg orally \[po\], twice…

Chronic Lymphocytic LeukaemiaModerate to Severe Cardiac Impairment

Estimated

~$25 – $1,500

Actual pay is set by the research site.

AstraZenecaNCT06651970

Phase 2

A Phase 2b / 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Combined Dose-Finding and Cardiovascular Outcome Study to Investigate the Efficacy and Safety of CSL300 (Clazakizumab) in Subjects With End Stage Kidney Disease Undergoing Dialysis

This is a two-part, phase 2b and phase 3 combined prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study. Part 1: Phase …

End Stage Kidney Disease

Estimated

~$75 – $3,000

Actual pay is set by the research site.

CSL BehringNCT05485961

Acute Infection in Mitochondrial Disease: An Observational Prospective Natural History Study of Metabolism, Infection and Immunity

Background: Mitochondrial disease is a rare disorder. It can cause poor growth, developmental delays, muscle weakness, and other symptoms. The disease is usua…

Mitochondrial Disease

Estimated

~$10 – $675

Actual pay is set by the research site.

National Human Genome Research Institute (NHGRI)NCT04419870

Observational

Assessment of Adolescent and Young Adult Vaccine Confidence and Missed Opportunities for Vaccination in the Mountain West (VACCINE CONFIDENCE - WEST): A Randomized Tailored Vaccine Messaging Intervention

his study will evaluate whether tailored vaccine messaging improves vaccination-related outcomes among parents and caregivers of adolescents. Participants will…

Vaccine ConfidenceAdolescent VaccinationVaccine Uptake

Estimated

~$10 – $750

Actual pay is set by the research site.

University of UtahNCT07878442

Phase 3

Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With Diabetes

The goal of this study is to learn how GLP-1 receptor agonist therapy affects muscle and bone health in older females over age 65 with type 2 diabetes. The ma…

Diabetes Mellitus, Type 2

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Emory UniversityNCT07428746