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Single-dose Prophylactic INdomethacin in Extremely Preterm Infants - A Multicenter Randomized Blinded Placebo-Controlled Trial (the SPIN RCT)

In Canada, about 900 babies each year are born very early (\<26 weeks of gestation) and have a high chance of dying or having a serious bleed in the brain. Fam…

Extreme PrematurityIntraventricular HemorrhageMorbidity;Newborn

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of British ColumbiaNCT06572917

Phase 2

A Phase II Study of Pembrolizumab, Olaparib, and Temozolomide in Patients With Glioma

This study will test the safety and effectiveness of a combination of pembrolizumab, olaparib, and temozolomide to see how well these drugs work when given tog…

Glioma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT05188508

Observational

WVU011625: The Role of Scheduled Intravenous Fluids in the Supportive Management of Patients Undergoing Chemo-radiotherapy for Head and Neck Cancer

Patients undergoing concurrent chemoradiotherapy (CCRT) for head and neck squamous cell carcinoma frequently experience treatment-related toxicities including …

Squamous Cell Carcinoma of HypopharynxSquamous Cell Carcinoma of LarynxSquamous Cell Carcinoma of Oropharynx+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

West Virginia UniversityNCT07784855

Phase 1

A First-in-human Phase I, Open-label, Multicentre, Dose Escalation Trial of BI 3819026 in Combination With Ezabenlimab in Patients With Unresectable Advanced or Metastatic Solid Cancers to Determine the Maximum Tolerated Dose (MTD) and Recommended Dose for Expansion (RDE)

This study is open to adults with advanced cancer. The purpose of this study is to find the highest dose of BI 3819026 that people with advanced cancer can tol…

Advanced Solid CancerMetastatic Solid Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Boehringer IngelheimNCT07607678

Phase 1

Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for Mismatch Repair Proficient (pMMR) Recurrent/Unresectable Endometrial Carcinoma

The purpose of this research study is to see if it is feasible to combine a fixed dose of pembrolizumab and a daily dose of oral lenvatinib, along with daily t…

Recurrent Endometrial CarcinomaUnresectable Endometrial Carcinoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Aaron WolfsonNCT05603910

Observational

Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success

This multi-center clinical trial is designed to assess the association of diabetes in a cornea donor with transplant success and loss of endothelial cells 5 ye…

Fuchs Endothelial Corneal DystrophyCorneal Endothelial Decompensation

Estimated

~$10 – $750

Actual pay is set by the research site.

Case Western Reserve UniversityNCT07217249

Observational

Cerebellar Transcranial Magnetic Stimulation and Cognitive Control

The purpose of this study is to examine whether cerebellar stimulation can be used to improve cognitive deficits and mood in patients with schizophrenia, autis…

SchizophreniaAutism Spectrum DisorderBipolar Disorder+2 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Krystal Parker, PhDNCT03217110

Phase 2

Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metastases

The investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 40-50% i…

Neoplasm MetastasesMetastases, Neoplasm

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Rutgers, The State University of New JerseyNCT05419518

Phase 2

Duloxetine Plus Exercise to Improve Physical Function in Veterans With Knee Osteoarthritis, Pain, and Psychological Comorbidity

Knee osteoarthritis (KOA) is one of the most common causes of chronic pain, mobility problems, and disability among United States Veterans. Many Veterans with …

Knee OsteoarthritisPainDepression

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07649291

Observational

Creating a Mobile Health Program for Teens With Congenital Heart Disease

The goal of this clinical trial is to learn if teens living with congenital heart disease like and will use Heart2Heart and if it affects how they think and fe…

Congenital Heart DiseaseHealth Behavior

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Kristen FoxNCT07764510

Observational

Pilot Trial of Network-Based Implementation Strategies to Increase Coalition Adoption and Early Implementation of Evidence-Informed Strategies for Child Health

Community coalitions bring together residents and organizations to improve child health, but they may need support to identify and put research-supported strat…

Childhood ObesityEvidence-Based PracticeFood Systems+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PittsburghNCT07804550

Phase 1

Digital Intradermal Hyaluronidase for Sclerodactyly in Systemic Sclerosis

Translational studies have demonstrated reduced hyaluronidase activity in the skin of patients with systemic sclerosis. It is thought this may contribute to th…

Systemic SclerosisSclerodactyly

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Medical University of South CarolinaNCT07697274