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An Investigational Study of CX-801 as Monotherapy and in Combination With PD1 Inhibition in Participants With Solid Tumors

The purpose of this first-in-human study, CTMX-801-101, is to characterize the safety, tolerability, and antitumor activity of CX-801 as monotherapy and in com…

Solid Tumor, Adult

Estimated

~$150 – $4,200

Actual pay is set by the research site.

CytomX TherapeuticsNCT06462794

Phase 1

Pilot Study of Scaling Busulfan Dose to Body Surface Area in Children Undergoing Hematopoietic Stem Cell Transplantation

The goal of this pilot study is to determine if scaling the first busulfan dose to Body Surface Area (BSA) in children with a BSA ≥0.5 m2 and using a BSA-bande…

Busulfan Pharmacokinetic AnalysisBusulfan DosingHematopoietic Stem Cell Transplant (HSCT)+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Children's Hospital of PhiladelphiaNCT07792369

Phase 2

Neural Target Identification for Functional Disability Associated With Alcohol Related Characteristics Among Veterans With Co-occurring Alcohol Use Disorder and Traumatic Brain Injury

The objectives of this VA Merit application are to identify a neural target unique to Veterans with co-occurring alcohol use disorder and mild traumatic brain …

Alcohol Use DisorderMild Traumatic Brain Injury

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT04043442

Phase 4

Impact of Probiotics Combined with Antibiotic Prophylaxis on Gut Microbiome Balance in Patients Undergoing Elective Orthopedic Surgery, Double-Blinded Randomized Controlled Trial

This study aims to evaluate whether probiotics can help maintain a healthy gut microbiome in patients receiving prophylactic antibiotics during elective orthop…

DysbiosisGut -microbiotaMicrobiome Analysis+2 more

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Acibadem Maslak HospitalNCT06791993

Observational

A Pilot Single-center Randomized Controlled Trial of Software Guided Point-of-care

The purpose of the study is to implement point of care ultrasound (POCUS) to generate preliminary, or pilot, data to support a full future POCUS study across m…

Heart Failure With Reduced Ejection Fraction

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Corewell Health WestNCT07828834

Phase 2

A Phase II Study of Cabozantinib for Patients With Recurrent or Progressive Meningioma

A Phase II Study of Cabozantinib for Patients with Recurrent or Progressive Meningioma

Meningioma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Baptist Health South FloridaNCT05425004

Observational

A Randomized, Multicenter, Multiregional, Pivotal Clinical Trial to Evaluate the Safety and Efficacy of IMD10 (Focused Ultrasound) in Combination With the Chemotherapy Regimen Consisting of Irinotecan Hydrochloride, Oxaliplatin, Fluorouracil (5-FU) and Leucovorin Improves Overall Survival Compared With the Chemotherapy Regimen Alone in Patients With Borderline Resectable Pancreatic Cancer or Locally Advanced Pancreatic Cancer

The purpose of this Interventional clinical trial is to evaluate safety and efficacy of 'IMD10 (focused ultrasound)' in the treatment of borderline resectable …

Pancreatic CancerBorderline Resectable Pancreatic CancerLocally Advanced Pancreatic Cancer

Estimated

~$10 – $1,050

Actual pay is set by the research site.

IMGT Co., Ltd.NCT07325214

Phase 1

A Phase 1/2 Clinical Study to Evaluate Safety, Tolerability, Biological Activity, and Initial Efficacy of Prime Editing (PM577a) for the Treatment of Wilson Disease (WD) in Adult and Adolescent Participants With at Least One Allele Harboring the p.H1069Q Mutation in ATP7B

The purpose of this study is to evaluate the safety, tolerability, biological activity, and initial efficacy of PM577a, an investigational Prime Editing therap…

Wilson DiseaseWilson's DiseaseWilsons Disease

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Prime Medicine, Inc.NCT07748403

Prospective Evaluation of Quality of Life and Utilities Following Surgical Treatment of Rectal Cancer

This study evaluates quality of life and utilities following surgical treatment of stage I-IV rectal cancer. This study may help researches learn more about qu…

Rectal AdenocarcinomaStage I Rectal Cancer AJCC v8Stage II Rectal Cancer AJCC v8+11 more

Estimated

~$10 – $750

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT02107105

Phase 4

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD: A Prospective Randomized Design

This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a…

Neuropathic PainPTSD

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Margaux M. Salas, PhDNCT06414356

Inside Liposarcoma Clinical Trials: Patient Experiences Shared While Undergoing Clinical Trials

The study seeks to delve into the firsthand experiences of patients diagnosed with liposarcoma who partake in a separate clinical research featuring a specific…

Liposarcoma

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Power Life Sciences Inc.NCT06039046

Observational

Ready, Set, Go! A Physical Fitness Intervention for Children With Mobility Challenges

Barriers to keeping and maintaining fitness as a young person with a disability exist across many domains of access to community locations such as fitness cent…

Cerebral PalsyMyelomeningoceleArthrogryposis+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT04789746