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27,407 recruiting studies available now

Advancing ADPKD Treatment With GLP-1RA: A Study of Glucagon-Like Peptide-1 Receptor Agonists' Efficacy, Safety, and Mechanism

The proposed clinical trial aims to assess if a year of treatment with a glucagon-like peptide 1 receptor agonist, a medication approved for weight management …

Autosomal Dominant Polycystic KidneyObesity

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Colorado, DenverNCT06582875

Phase 3

A Multicenter, Open-Label, Long-term, Extension Study to Evaluate the Safety and Tolerability of Dazodalibep in Participants With Sjögren's Syndrome (SS)

The primary objective of this study is to evaluate the long-term safety and tolerability of dazodalibep.

Sjögren's Syndrome

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AmgenNCT06747949

Phase 1

Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma

CAR-T cell treatment of refractory lymphoma has shown success, particularly with CD-19 targeted CAR-T cells, however, many participants are refractory or relap…

Relapsed CLLRefractory CLLRefractory Lymphoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Paolo Caimi, MDNCT06916767

Phase 2

An Open Label, Multicenter Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Only subjects that have completed TILS-021, a Phase 2a Randomized, Double-Blind, Placebo-Controlled, Multicenter Dose-Ranging Study of Nasal Foralumab in Non-A…

Non-Active Secondary Progressive Multiple Sclerosis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Tiziana Life Sciences LTDNCT06890923

Observational

Virtual Reality Visual Field Testing as an Alternative to Standard Automated Perimetry in Childhood Eye Disease

The purpose of this study is to test a new way of measuring the peripheral vision (called a visual field test) using a device which can be worn as goggles rath…

Visual Field Defect, Peripheral

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT05150197

Observational

Cardiometabolic Risk Effects of Short-term Cessation of Effective Neurostimulation Therapy in OSA

Hypoglossal nerve stimulation (HGNS) is an implantable therapy that treats obstructive sleep apnea. The study will evaluate the effect of this treatment on ca…

Obstructive Sleep ApneaObstructive Sleep Apnea of Adult

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT06720545

Phase 1

A Pilot Safety and Feasibility Study of Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Treatment for relapsed/refractory multiple myeloma continues to evolve with the approval of highly effective anti-BCMA CAR T therapies in recent years. However…

Multiple Myeloma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Washington University School of MedicineNCT06623630

Mechanisms of Resistance to PSMA Radioligand Therapy: Radiation Resistance Versus Dose

This is a multicenter, correlative study to existing Lutetium based prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) trials and use…

Prostate Cancer

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT05435495

Phase 1

A Pilot Study to Evaluate the Immunogenic Effects of Window-of-Opportunity Fractionated Stereotactic Radiotherapy Combined With Atezolizumab for Patients With Newly Diagnosed WHO CNS Grade 4 Glioma (Glioblastoma Multiforme)

This is a single-arm pilot study that will recruit 12 patients with newly diagnosed Glioblastoma, a malignant brain tumor with a poor prognosis. Patients will …

Glioblastoma Multiforme

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Stony Brook UniversityNCT05423210

Characterization of the Symptom Experience of Patients With Cutaneous Melanoma Receiving Immune Checkpoint Inhibitor Therapy

The introduction of immune checkpoint inhibitors (ICIs) for the treatment of patients with stages IIB to IV cutaneous melanoma resulted in dramatic improvement…

Cutaneous MelanomaCutaneous Melanoma, Stage IIICutaneous Melanoma by AJCC V7 Stage+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT07148245

Observational

Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans (CDA 22-135)

The current proposal aims to refine and examine an intervention called Calm Moms. Calm Moms is a web-based treatment program designed to reduce anxiety, stress…

Trauma-related Mental Health Symptoms

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT06906185

Observational

Safety and Performance of the ThecaFlex DRx™ System Port and Catheter for Chronic Intrathecal Access, Cerebrospinal Fluid (CSF) Aspiration, and DElivery of Nusinersen in Spinal Muscular Atrophy (SMA) Patients Resistant to Lumbar PunctuRE Trial (PIERRE)

The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects…

Spinal Muscular AtrophySpine DeformityScoliosis

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Alcyone Therapeutics, IncNCT05866419