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27,293 recruiting studies available now

A Randomized Phase II Trial of Nivolumab and Ipilimumab Compared to Nivolumab Monotherapy in Patients With Deficient Mismatch Repair System Recurrent Endometrial Carcinoma

This phase II trial tests whether the combination of nivolumab and ipilimumab is better than nivolumab alone to shrink tumors in patients with deficient mismat…

Endometrial AdenocarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Dedifferentiated Carcinoma+6 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05112601

Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc. In this imaging t…

Heart FailureLiver FibrosisCardiac Transplant Rejection+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Arunark KolipakaNCT01757730

Phase 3

An International, Prospective, Open-label, Multi-center, Randomized Phase III Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) Versus Observation to Delay Castration or Disease Recurrence in Adult Male Patients With Prostate-specific Membrane Antigen (PSMA) Positive Oligometastatic Prostate Cancer (OMPC)

The purpose of this study is to evaluate the efficacy and safety of lutetium (177Lu) vipivotide tetraxetan (AAA617) in participants with oligometastatic prosta…

Oligometastatic Prostate Cancer (OMPC)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT05939414

Observational

From Screening to Action: Implementing Navigation Interventions for Patients With Breast Cancer and High-risk Social Determinants of Health

This study aims to assess how individual patient social stressors are associated with barriers to care by analyzing a patient navigator system. Patient navigat…

Breast CancerCancer of Breast

Estimated

~$10 – $750

Actual pay is set by the research site.

Washington University School of MedicineNCT07781800

Investigating the Therapeutic Impact of Cannabinoids on Neuroinflammation and Neurobiological Underpinnings of Suicide Ideation in Veterans With PTSD

This study will be the first to use brain imaging to explore how cannabis affects the brain and inflammation in U.S. military veterans with PTSD. It builds on …

PTSDSuicidal Thoughts and BehaviorsPTSD Symptoms+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Wayne State UniversityNCT07222306

Observational

Effectivity of P1821, a Novel Tongue Strengthening and Endurance Enhancing Speech Flow Exercise

The P1821 initiative constitutes an innovative intervention specifically engineered to enhance tongue muscular strength and endurance. The primary objective of…

AnkyloglossiaImpairment of SpeechSlurred Speech

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Dream Video LLCNCT07719582

Phase 2

A Phase 2/3, Randomized, Open-label, Active-comparator-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of Bomedemstat (MK-3543) Versus Best Available Therapy in Participants With Polycythemia Vera Who Have an Inadequate Response to or Are Intolerant to Hydroxyurea

Researchers are looking for new ways to treat polycythemia vera (PV). People with PV may receive treatment to lower the number of red blood cells in the blood,…

Polycythemia Vera

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07722611

Phase 1

Targeting CD38 With Daratumumab in Primary Antiphospholipid Syndrome: A Phase 1b Dose Escalation Safety Trial (ITN093AI)

The purpose of this study is to see if the study medication, daratumumab, is safe to treat individuals with Anti-Phospholipid Syndrome (APS). Three daratumuma…

Autoimmune Disorders

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT05671757

Phase 1

A Phase 1, First-in-Human Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Participants With Prostate Cancer

There are many treatment options for men with various stages of prostate cancer. Some treatments work well for a while but can cause medical problems in some m…

Hormone-refractory Prostate Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT05997615

Observational

Early Feasibility Study of the DUO Transcatheter Tricuspid Coaptation Valve System in Patients With Tricuspid Regurgitation

The study is an early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function of the DUO Transcat…

Tricuspid RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

CroiValve LimitedNCT05913908

Phase 1

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

Background: Neuroblastoma is a type of cancer that causes tumors in nerves. It affects mainly infants and toddlers, and it causes about 15 percent of cancer-r…

Neuroblastoma

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06995872

Phase 2

A Double Blind, Placebo-controlled Trial of LAM-001 for Treatment of Sarcoidosis Associated Pulmonary Hypertension (SAPH)

A Phase 2, Randomized, Double-Blind, Multi-Dose, Placebo-Controlled Study to Evaluate the Efficacy and Safety of LAM-001 (Inhaled Sirolimus) in Adults with Sar…

Sarcoidosis Associated Pulmonary Hypertension

Estimated

~$75 – $2,800

Actual pay is set by the research site.

IRulya Therapeutics Inc.NCT07886554