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27,293 recruiting studies available now

Efficacy of Intravenous Sub-Dissociative Ketamine Versus Intravenous Morphine in Children With Acute Pain

Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences. Morphine i…

Abdominal PainIsolated Extremity FracturePain+1 more

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Columbia UniversityNCT06835504

Phase 1

A Randomized, Double-blind, Placebo-controlled Single Ascending Dose and Open-label Multi-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ALN-APP in Adult Patients With Early-onset Alzheimer's Disease (EOAD)

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose and multiple doses of ALN-A…

Early-Onset Alzheimer Disease

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Alnylam PharmaceuticalsNCT05231785

Observational

The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms

The goal of this study is to determine if a developed protocol involving modulated auditory stimulation is better than non-modulated auditory stimulation in re…

AnxietyDepression

Estimated

~$10 – $1,125

Actual pay is set by the research site.

HealthPartners InstituteNCT06701578

Phase 1

A Phase 1, Randomized, Double-Blind, Comparator-Controlled Dose-Escalation Study to Evaluate the Safety, Tolerability, and Immunogenicity of V132 in Healthy Older Participants

The goal of this study is to learn about the safety and immune response to the V132 vaccine in healthy older adults.

Healthy

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07712575

Phase 1

An Open-label Multi-Cohort Phase 1b/2 Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease and No Actionable Genomic Alterations

Non small cell lung carcinoma (NSCLC) is the most frequently occurring histologic subtype of lung cancer and is the leading cause of cancer-related deaths worl…

Non Small Cell Lung Carcinomac-MET

Estimated

~$150 – $4,500

Actual pay is set by the research site.

AbbVieNCT06772623

Phase 3

Phase 3, Open-label, Single-dose, Multicenter Study Investigating Efficacy, Safety, and Tolerability of CSL222 (Etranacogene Dezaparvovec) Administered to Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

This is a phase 3, prospective, open-label, single-arm, single-dose, multicenter study investigating the efficacy, safety, and tolerability of CSL222 (AAV5-hFI…

Hemophilia B

Estimated

~$50 – $2,250

Actual pay is set by the research site.

CSL BehringNCT07080905

Observational

Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response

The goal of this study is to investigate whether the therapeutic response of pancreatic tumors can be accurately assessed using quantitative DCE-MRI, when the …

Pancreatic Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Ohio State UniversityNCT04588025

Phase 2

Cashew Allergy Study in Children: Assessing Desensitization, Efficacy, and Safety (CASCADES Study)

The CASCADES study will investigate the safety and efficacy of sublingual immunotherapy (SLIT) for the treatment of cashew allergy in children ages 1-11 years …

Cashew Nut AllergyTree Nut Allergies

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of North Carolina, Chapel HillNCT07170540

Phase 1

Safety of Cultured Allogeneic Adult Umbilical-cord or Placental Derived Mesenchymal Stem Cell Intrathecal Injection for the Treatment of Spinal Cord Injury

This trial will study the safety and efficacy of intrathecal injection of cultured allogeneic adult umbilical-cord or placental derived mesenchymal stem cells …

Spinal Cord Injuries

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Foundation for Orthopaedics and Regenerative MedicineNCT05018793

Phase 1

A Phase 1b Study of Gemcitabine and Leflunomide in Patients With Unresectable Pancreatic Cancer

This phase Ib trial tests the safety, side effects, and best dose of leflunomide in combination with gemcitabine in treating patients with pancreatic cancer th…

Advanced Pancreatic AdenocarcinomaStage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

City of Hope Medical CenterNCT06454383

ObservationalRemote eligible

Delivering Transcutaneous Auricular Neurostimulation to Reduce Heavy Menstrual Bleeding: The LUNA Study

The LUNA study is a prospective, randomized, double-blind, sham-controlled, decentralized clinical trial in participants with heavy menstrual bleeding of no kn…

Heavy Menstrual Bleeding

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Spark Biomedical, Inc.NCT07326722

Observational

Improving Colorectal Cancer Screening Decisions Through Consideration of Life Expectancy

The purpose of this study is to improve life-expectancy concordant colorectal cancer screening for adults over 75 years through design and testing of a life ex…

Colorectal Cancer Control and Prevention

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Kathryn MartinezNCT07141901