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3,222 recruiting studies matching your filters

A Phase I/II Study of Hyperpolarized 13C MRI as a Biomarker of Aggressiveness & Response to Therapy in Patients With Advanced Solid Tumors

This is a single center prospective imaging study investigating the utility of hyperpolarized 13C-pyruvate +/-13C,15N-Urea/ metabolic MR imaging. The current p…

Advanced Solid Tumor

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Robert Bok, MD, PhDNCT05599048

Observational

The Effects of Vibratory Stimuli on Joint Health and Post-traumatic Osteoarthritis Risk Following Anterior Cruciate Ligament Injury

The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and se…

Osteoarthritis, KneeAnterior Cruciate Ligament InjuriesPost-traumatic Osteoarthritis+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of North Carolina, Chapel HillNCT04875052

Phase 1

A Phase 1a/1b, First-in-Human, Open-Label, Multi-Center, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LB-LR1109, When Administered Alone for the Treatment of Advanced or Metastatic Solid Tumors, and in Combination With Atezolizumab for the Treatment of Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

This is a Phase 1a/1b, first-in-human (FIH), multi-center, open-label, non-randomized, dose escalation study, designed to determine the Maximum tolerated dose(…

Non-small Cell Lung Cancer(NSCLC)Head and Neck Squamous Cell Carcinoma(HNSCC)Renal Cell Carcinoma(RCC)+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

LG Chem

Phase 1

Feasibility of Treating Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma With Zanubrutinib in Combination With the BCL2 Inhibitor, Sonrotoclax, Focusing on Access for Underrepresented Ethnic/Racial Minorities

This phase I trial tests zanubrutinib in combination with sonrotoclax for treating underrepresented ethnic and racial minorities with B-cell non-Hodgkin lympho…

Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRecurrent Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaRecurrent Diffuse Large B-Cell Lymphoma+16 more

Estimated

Phase 1

Phase I Study of Adoptive Immunotherapy With CD8+ and CD4+ Memory T Cells Transduced to Express an HA-1-Specific T Cell Receptor (TCR) for Children and Adults With Recurrent Acute Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation (HCT)

This phase I trial studies the side effects and best dose of CD4+ and CD8+ HA-1 T cell receptor (TCR) (HA-1 T TCR) T cells in treating patients with acute leuk…

Juvenile Myelomonocytic LeukemiaRecurrent Acute Biphenotypic LeukemiaRecurrent Acute Undifferentiated Leukemia+26 more

Observational

Evaluating the Safety and Diagnostic Utility of Cardiac MRI in Patients With Abandoned, Fractured Endocardial Leads or Permanent Epicardial Leads

This is a prospective cohort study looking to systematically evaluate the safety of conducting cardiac Magnetic Resonance Imaging (MRI) in this high-risk patie…

Abandoned Endocardial LeadsBroken Endocardial LeadsPermanent Epicardial Leads

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Baylor Research InstituteNCT07679009

Phase 2

Tirzepatide With Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer in Overweight and Obese Women

This phase II trial studies whether adding tirzepatide injections to a levonorgestrel intrauterine device (LNG-IUD) improves pathologic response (absence of ca…

Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial NeoplasiaFIGO Grade 1 Endometrial Endometrioid Adenocarcinoma

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07349641

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

This study is being done to collect tissue samples to test how accurately a tumor response platform, Elephas, can predict clinical response across multiple typ…

Early Stage Triple-Negative Breast CarcinomaMetastatic Bladder Urothelial CarcinomaMetastatic Cervical Carcinoma+24 more

Estimated

~$10 – $750

Observational

Developing a Sleep Health Intervention for Shift Workers

The aim of this study is to pilot test a comprehensive, personalized, media-augmented telehealth intervention ("SWISH") designed to improve sleep health among …

Shift Work Type Circadian Rhythm Sleep DisorderInsomnia, Psychophysiological

Estimated

~$10 – $750

Actual pay is set by the research site.

Oregon State UniversityNCT06384742

Phase 4

The DEterminig Statin Intolerance for Rosuvastatin Trial

The DESIFOR pilot study was conducted to determine the feasibility of utilizing an n-of-1 trial to facilitate tolerance of unblinded rosuvastatin in patients w…

Statin TherapyStatin Adverse ReactionStatin

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Minneapolis Heart Institute FoundationNCT06804980

Phase 2

Metastatic Non-Familial Adenocarcinoma Maintenance Therapy With DZ-002: Heptamine Carboxymethine Dye Conjugate

The goal of this clinical trial is to learn if drug DZ-002 works to treat adults with metastatic pancreatic adenocarcinoma. It will also learn about the safety…

Metastatic Pancreatic AdenocarcinomaPancreatic Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Hoag Memorial Hospital PresbyterianNCT07344220

Observational

PBM-LEF Study: The Impact of PBM on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer Patients: A Feasibility Study

Radiation fibrosis syndrome (RFS) is a general side effect of radiation therapy (RT) which can adversely impact patients chronically over years typically trigg…

Radiation LymphedemaRadiation FibrosisHead and Neck Cancer

Estimated

~$10 – $1,125

Actual pay is set by the research site.

NYU Langone HealthNCT06708754