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3,222 recruiting studies matching your filters

A Phase 1/2, Multicenter, Open-label Study of REM-422, a MYB mRNA Degrader, in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma

The goal of this study is to determine the safety and antitumor effects of REM-422, a MYB mRNA degrader, in people with advanced Adenoid Cystic Carcinoma (ACC)

Adenoid Cystic CarcinomaMetastatic Adenoid Cystic CarcinomaRecurrent Adenoid Cystic Carcinoma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Remix TherapeuticsNCT06118086

Phase 1

Evaluation of the Pharmacokinetics, Biodistribution and Radiation Dosimetry of [18F]MODAG-009 Positron Emission Tomography (PET) Radiotracers in Adult Healthy Volunteers

This is an open-label, single-center, phase 1 study to further characterize \[18F\]MODAG-009 in Healthy Volunteers (HV). Approximately 6 participants will be e…

Healthy Adult

Estimated

~$500 – $10,500

Actual pay is set by the research site.

MODAG GmbHNCT07617688

Population-Based Analysis of Neoplastic Changes in Cystic Lesions of the Pancreas.

Pancreatic cysts are found incidentally on 15-50% of CT and MRIs for all indications and their prevalence is increasing. Many of these cysts may be precursors …

Pancreatic CystPancreatic NeoplasmsPancreatic Cancer+5 more

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT04291651

Phase 1

A Phase 1 Open-label, First-in-human, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of 225Ac-PSMA-Trillium in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Researchers are looking for a better way to treat participants who have metastatic castration-resistant prostate cancer (mCRPC). mCRPC is a cancer of the pros…

Advanced Metastatic Castration-resistant Prostate CancerProstate Specific Membrane Antigen (PSMA) Expression

Estimated

~$150 – $4,500

Actual pay is set by the research site.

BayerNCT06217822

Phase 2

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR2 Gene Fusions or Other FGFR Genetic Alterations

This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread from where it first started…

Advanced Pancreatic CarcinomaMetastatic Pancreatic CarcinomaStage II Pancreatic Cancer AJCC v8+2 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Sameek RoychowdhuryNCT06906562

Phase 1

Phase 1 Study of Cemiplimab - TP Induction Chemotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck

The purpose of this research study is to determine the safety and tolerability of two dosing schedules of cemiplimab given in combination with cisplatin and do…

Locally Advanced Head and Neck Squamous Cell Carcinoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Krzysztof MisiukiewiczNCT05376553

Phase 1

Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy Delivery

The purpose of this study is to characterize the reduction in PSMA-avid tumor volume and metastasis-directed radiotherapy treatment intensity facilitated by PE…

Prostate CancerCastration Sensitive Prostate CancerMetastatic Prostate Cancer+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Texas Southwestern Medical CenterNCT07674771

Observational

The Mind After Midnight: Mechanistic Examination of Nocturnal Wakefulness as a Suicide Risk Factor

This study examines whether wakefulness during the biological night (2:00-4:00 AM) is associated with increased negative mood, impaired decision-making, and su…

Suicidal IdeationCircadian Rhythm DisordersSleep Deprivation+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ArizonaNCT07438912

Phase 4

The Use of a Novel Post-Operative Thoracolumosacral Orthosis for Prevention of Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery

Proximal junctional kyphosis (PJK) is a common post-operative radiographic finding after surgery for adult spinal deformity (ASD) patients. Although the clinic…

Proximal Junctional KyphosisAdult Spinal Deformity SurgeryThoracolumbosacral Orthosis

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Hospital for Special Surgery, New YorkNCT06491030

Observational

Randomized Trial Comparing Parallel Versus Perpendicular Technique for Lumbar Medial Branch Radiofrequency Neurotomy

Low back pain is a leading cause of disability worldwide. The lumbar zygapophyseal joints (z-joints) are estimated to be the source of low back pain between 10…

Back Pain Without RadiationLow Back PainLumbar Radiofrequency Neurotomy

Estimated

~$10 – $750

Actual pay is set by the research site.

Vanderbilt University Medical CenterNCT03912519

Observational

Comparative Analysis of Efficiency, Technical Performance, and Environmental Cost Between Reprocessed and New Coblator Wands in Intracapsular Tonsillectomies and Adenoidectomies

This study will address the gap in coblator wands by comparing the performance of reprocessed coblator wands with new wands in terms of efficiency and technica…

TonsillectomyAdenoidectomy

Estimated

~$10 – $750

Actual pay is set by the research site.

Montefiore Medical CenterNCT07635719

Phase 1

A Phase I/IIa, Dose Escalation Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of Intraductal Administration of RXRG001 to Parotid Gland(s) in Adults With Radiation-Induced Xerostomia and Hyposalivation

This is a first-in-human clinical study to evaluate the safety, tolerability and efficacy of RXRG001 administered in the ducts of the parotid glands in adult p…

Radiation-Induced Xerostomia and Hyposalivation

Estimated

~$150 – $4,200

Actual pay is set by the research site.

RiboX Therapeutics Ltd.NCT06714253