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3,080 recruiting studies matching your filters

An Open-label, Multi-center, Phase I/Ib Study of IEV407 as a Single Agent and in Combination With Endocrine Therapy in Patients With Advanced Hormone Receptor Positive, HER2- Negative Breast Cancer

The purpose of this study is to evaluate the safety, tolerability and preliminary activity of IEV407 as a single agent and in combination with endocrine therap…

Advanced HR+/HER2- Breast Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT07604571

Phase 2

A Phase II, Multi-Center Study to Evaluate the Efficacy and Safety of Volrustomig as Monotherapy or in Combination With Anti-cancer Agents in Participants With Advanced/Metastatic Solid Tumors

eVOLVE-02 study will evaluate the efficacy and safety of volrustomig as monotherapy or in combination with anti-cancer agents in participants with advanced/met…

Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy)Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy)+2 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Phase 1

A Phase 1 Trial Of Safety And Initial Efficacy Of Vagal Nerve Blockade For Cancer-Induced Cachexia In Patients With Metastatic Pancreatic Adenocarcinoma

The goal of this clinical research study is to learn about the safety and tolerability of the OnVagus device when used by patients who have metastatic pancreat…

Metastatic Pancreatic Adenocarcinoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT07700212

Chronic Radiation Cystitis and Effect of Hyperbaric Oxygen Therapy on Patient Reported Outcomes and Urine Inflammatory Biomarkers

Collection of urine, blood, and tissue samples from patients undergoing hyperbaric oxygen therapy

Radiation CystitisUrinary Tract Infection (Diagnosis)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Rachel A. MosesNCT07368647

Phase 1

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

3CAR is being done to investigate an immunotherapy for patients with solid tumors. It is a Phase I clinical trial evaluating the use of autologous T cells gene…

Pediatric Solid TumorOsteosarcomaRhabdomyosarcoma+13 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

St. Jude Children's Research HospitalNCT04897321

Phase 2

Neostigmine and Glycopyrrolate for the Treatment of Post Dural Puncture Headache After Known Dural Puncture With a Tuohy Needle: A Pilot Study

The purpose of this study is to evaluate Neostigmine and Glycopyrrolate to treat post-dural puncture headache (PDPH) to reduce the proportion of postpartum wom…

Post-Dural Puncture Headache

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Mayo ClinicNCT05116930

Phase 1

Open Label Phase 1 and Target Validation Study of ONC206 in Children and Young Adults With Newly Diagnosed or Recurrent Diffuse Midline Glioma (DMG), and Other Recurrent Primary Malignant Central Nervous System (CNS) Tumors

This phase I trial studies the effects and best dose of ONC206 alone or in combination with radiation therapy in treating patients with diffuse midline gliomas…

Diffuse Midline Glioma (DMG)GlioblastomaRecurrent Ependymoma+5 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Sabine Mueller, MD, PhDNCT04732065

Phase 1

Study Evaluating [18F]NOTA-ABY030 for Safety and Tolerability of Indeterminate Primary and/or Metastatic Disease in Head and Neck Squamous Cell Carcinoma

This Phase I, single-institution, open-label study will evaluate the safety, tolerability, and diagnostic performance of \[18F\]NOTA-ABY030 PET/CT in patients …

SCC - Squamous Cell CarcinomaRadiotracerHead and Neck Squamous Cell Carcinoma+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Vanderbilt-Ingram Cancer CenterNCT07217028

Phase 1

A Phase 1/2 Study to Evaluate the Safety and Efficacy of MK-2870 Monotherapy or in Combination With Other Anticancer Agents in Gastrointestinal Cancers

Researchers want to learn if sacituzumab tirumotecan (MK-2870) alone or with other treatments can treat certain gastrointestinal (GI) cancers. The GI cancers b…

Colorectal CancerPancreatic Ductal AdenocarcinomaBiliary Tract Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT06428409

Phase 2

A Proof-of-Concept Open-Label Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of CSTI-500 in Participants With Prader-Willi Syndrome

This is a proof-of-concept, open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CSTI-500 in participants …

Prader-Willi Syndrome

Estimated

~$75 – $2,800

Actual pay is set by the research site.

ConSynance TherapeuticsNCT07348601

Phase 3

Open-Label, Multiple-Dose, 52-Week Study + 24-Month Long-Term Safety Extension to Evaluate the Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Deficiency or Absence of Endogenous Testosterone Due to Primary or Secondary Hypogonadism

This is a 52-week open label single arm study + 24-Month long-term safety extension to investigate the effects of XYOSTED, as testosterone replacement therapy,…

Hypogonadism, Male

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Halozyme TherapeuticsNCT06689085

Proton Therapy Patient Registry

The purpose of this study is to establish a database (or "registry") of patients treated with proton beam therapy at the University Hospitals (UH) Proton Thera…

Treatment With Proton Beam Radiation Therapy

Estimated

~$10 – $750

Actual pay is set by the research site.

Case Comprehensive Cancer CenterNCT02986048