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3,234 recruiting studies matching your filters

A Phase 1, Open-Label, Multicenter Study of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

To evaluate the safety, tolerability, and DLTs and determine the MTD and/or RDE(s) of INCA33890 in participants with select advanced or metastatic solid tumors.

Solid TumorsAdvanced Solid TumorsMetastatic Solid Tumors

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Incyte CorporationNCT05836324

Phase 1

Pilot Evaluation of Focused Ultrasound Ablation and Intratumoral PolyICLC in Patients With Regionally Advanced Resectable Melanoma Who Are Receiving Neoadjuvant Immunotherapy

This study is for adult patients with advanced melanoma who are receiving immunotherapy and who are planning on having surgery for their cancer. All participan…

Advanced Melanoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of VirginiaNCT06472661

Phase 1

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

To learn if the combination of blinatumomab and asciminib can help to control Ph+ ALL.

Philadelphia Chromosome-PositiveAcute Lymphoblastic Leukemia

Estimated

~$150 – $3,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT06308588

Phase 2

A Phase 2 Study of Fludarabine, Cytarabine, Filgrastim-sndz,Gemtuzumab Ozogamicin and Idarubicin in Newly Diagnosed Core Binding Factor Associated Acute Myelogenous Leukemia

This phase II trial studies the side effects and how well fludarabine phosphate, cytarabine, filgrastim-sndz, gemtuzumab ozogamicin, and idarubicin hydrochlori…

Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1+7 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Observational

PEACE Study: Psychophysical Enhancement to Augment Conservative and Epidural Steroid Injection Outcomes: A Multi-Center International Randomized Trial

Back pain is the leading cause of disability and military medical boards across the globe. Epidural steroid injections (ESI) are the most commonly performed pa…

Lumbosacral Radiculopathy

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT07498140

Observational

PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

The PRIME Study is a first-in-human early feasibility study to evaluate the initial clinical safety and device functionality of the Neuralink N1 Implant and R1…

Tetraplegia/TetraparesisQuadriplegiaCervical Spinal Cord Injury+3 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Neuralink CorpNCT06429735

Phase 4

A Randomized, Placebo Controlled Trial of Nitrous Oxide/Oxygen Plus Standard Care Versus Standard Care Alone During In-office Intradetrusor onabotulinumtoxinA (Botox) Injections

The goal of this clinical trial is to assess if a mix of nitrous oxide and oxygen can improve pain control during bladder Botox injections. The primary questio…

Overactive BladderNeurogenic BladderUrge Incontinence+7 more

Estimated

~$25 – $1,400

Actual pay is set by the research site.

TriHealth Inc.NCT07387315

An Observational, Cross-Sectional Study Evaluating the Impact of Long-Term Supplement Use on Biological Age and Metabolic Health Markers - The BioAge Trial

This study will evaluate whether dietary supplement use (\> 1 year) is associated with differences in biological age relative to chronological age, as well as …

Generally Healthy Adults Who Are Long-term Supplement Users

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Shaklee CorporationNCT07755943

Observational

RED KARD: Reducing Disparities in Knee Arthroscopy for Adolescents

Hundreds of thousands of youth athletes require surgery for knee injuries annually. The incidence of operative knee injuries has skyrocketed, but surgery can b…

Knee InjuryACL InjuryMeniscus Tear+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Ann & Robert H Lurie Children's Hospital of ChicagoNCT07580625

Phase 2

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

Rectal cancer patients who do not achieve a complete response to standard of care chemotherapy and radiation often require surgical resection as part of curati…

Rectal AdenocarcinomaRectal Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Colorado, DenverNCT07292298

Phase 1

A Phase 1b Safety and Pharmacodynamic Study of MER Tyrosine Kinase Inhibitor, MRX-2843, in Combination With Osimertinib in Advanced EGFR Mutant Non-Small Cell Lung Cancer

This phase Ib trial evaluates the best dose and side effects of MRX-2843 when given in combination with osimertinib in treating patients with EGFR gene mutant …

Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Emory UniversityNCT04762199

Phase 2

Phase 2, Randomized, Prospective, Open-Label, Parallel-Arm, Dose Optimization Study to Investigate the Safety, Tolerability, PK/PD, and Anti- Tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian Cancer.

The purpose of this study is to evaluate the optimal dose of 2X-121 as single agent therapy at 600 mg daily (split BID 200 mg morning + 400 mg evening) compare…

Advanced Ovarian Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Allarity TherapeuticsNCT03878849