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3,226 recruiting studies matching your filters

Can Increasing Motor Evoked Potential Size Improve Upper Extremity Motor Function in Individuals With Incomplete Spinal Cord Injury?

The purpose of this study is to examine the relationship between common clinical assessments and measurements of the function of brain-spinal cord-muscle conne…

Spinal Cord InjuriesQuadriplegia

Estimated

~$10 – $750

Actual pay is set by the research site.

Medical University of South CarolinaNCT05321017

Phase 1

A Phase 1, Randomized, Single-dose, Open-label, Two-way, Crossover Study to Evaluate the Effect of Food on AJ201, and to Evaluate the Safety, Tolerability, and Pharmacokinetics of AJ201 in Japanese and White Healthy Male Participants

This is a Phase 1, randomized, single-dose, open-label, two-way crossover study to evaluate the effect of food on AJ201, and to evaluate the safety, tolerabili…

Healthy Male AdultsFood Effect in Healthy Volunteers

Estimated

~$500 – $10,500

Actual pay is set by the research site.

AnnJi Pharmaceutical Co., Ltd.NCT07549919

Observational

The Effect of Salt Water Gargling on Swallowing Dysfunction Following Multi-Level Anterior Cervical Discectomy and Fusion (ACDF): A Randomized Control Trial

The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or…

Degeneration SpineCervical RadiculopathyCervical Stenosis+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Southern CaliforniaNCT06475365

Phase 1

A Phase 1 Study of the Safety and Tolerability of DUVAX, a Dual-Target Alzheimer's Vaccine (Amyloid-Beta and Tau), in Healthy Volunteers

This Phase 1 study will test the safety and immune response of the investigational vaccine DUVAX in healthy adults. Participants will be randomly assigned to r…

Alzheimer DiseaseAlzheimer Disease (AD)Preclinical Alzheimer's Disease

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Nuravax, Inc.NCT07142278

Phase 1

An Open-Label, Multicenter, First-in-Human, Phase 1 Dose-Escalation and Multicohort Expansion Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody targeting th…

Ewing SarcomaColorectal Adenocarcinoma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Inhibrx Biosciences, IncNCT03715933

Observational

The Role of Medically Tailored Groceries in Mitigating Food Insecurity and Improving Pregnancy Outcomes Through Clinic-Community Partnerships

Medically tailored groceries (MTG), involving grocery items to be prepared at home, selected by a nutritional professional based on a treatment plan, is a grow…

Estimated

~$10 – $750

Actual pay is set by the research site.

Case Western Reserve UniversityNCT06965530

Phase 1

A Phase 1/2, First-in-Human, Open-Label, Dose Escalation and Expansion Study of STAR0602, a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule, in Subjects With Unresectable, Locally Advanced, or Metastatic Solid Tumors That Are Antigen-rich (START-001)

This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in co…

Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Marengo Therapeutics, Inc.

Phase 1

A Phase 1/2, Open-Label, Dose-Escalation, Dose-Enrichment, and Dose-Expansion Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of BLU-924 (SAR449336) as Monotherapy and Combination Therapy in Participants With Advanced Pancreatic Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer Harboring KRAS Mutations

A first in human study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of BLU-924 / SAR449336, a pan-KRAS inhibitor, in particip…

Advanced Solid TumorNon-Small Cell Lung CancerColorectal Neoplasms+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Blueprint Medicines CorporationNCT07629960

Phase 1

Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma

This feasibility study will assess the clinical potential of a new imaging approach to detect viable high grade glioma (HGG) in pediatric and adult patients af…

High Grade Glioma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Alabama at BirminghamNCT05632562

Phase 2

A Phase 2 Multicenter, Open-Label, Single-Arm Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy

This is a Phase 2, open-label, multicenter, single-arm study of NRC-2694-A in combination with paclitaxel in patients with R/M HNSCC with progression on or aft…

CarcinomaRecurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Estimated

~$75 – $2,800

Actual pay is set by the research site.

NATCO Pharma Ltd.NCT05283226

Phase 1

Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)

This study will evaluate the feasibility of using a sub-therapeutic dose of a fluorine-18 analogue of NP-59 (\[18F\]FNP-59) to image the adrenal gland. Some pa…

RadiotracerHypertensionCholesterol

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Benjamin VigliantiNCT04546126

Phase 4

A Randomized Trial of Postoperative Steroid Use Following Posterior Spinal Fusion in 100-subject Adolescent Idiopathic Scoliosis (AIS) and Neuromuscular Scoliosis (NMS)

The goal of this randomized clinical trial is to compare the immediate use of steroids after surgery for accelerated discharge in adolescent idiopathic scolios…

Neuromuscular ScoliosisAdolescent Idiopathic Scoliosis

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Children's Hospital Los AngelesNCT06023043