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3,226 recruiting studies matching your filters

Atezolizumab With Platinum and Etoposide Chemotherapy Followed by Cystectomy for Patients With Localized Small Cell Neuroendocrine Bladder Cancer

This is a single arm, Phase II trial involving the use of atezolizumab plus platinum and etoposide for patients with locally advanced urothelial cancer. The pr…

Small Cell Neuroendocrine Carcinoma of BladderBladder CancerUrothelial Carcinoma Bladder

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT05312671

Phase 2

A Phase II Trial Of Lovastatin And Pembrolizumab In Patients With RM HNSCC (LAPP)

This phase II trial tests how well lovastatin and pembrolizumab work in treating patients with head and neck cancer that has come back after a period of improv…

Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related Neck Squamous Cell Carcinoma of Unknown PrimaryMetastatic Head and Neck Squamous Cell Carcinoma+19 more

Estimated

Observational

The Impact of Blood Flow Restriction Training in Adolescents After ACL Reconstruction: A Randomized Controlled Trial

While there are a number studies that have reported on the use of blood flow restriction training (BFRT) in the adult population, there is limited information …

Anterior Cruciate Ligament InjuriesKnee InjuriesQuadriceps Muscle Atrophy

Estimated

~$10 – $750

Actual pay is set by the research site.

Connecticut Children's Medical CenterNCT05754632

Phase 1

A Phase 1b, Open Label, Single and Multiple Ascending Dose-escalation Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Subcutaneous Adenylosuccinic Acid (ASA) in Two Siblings With Adenylosuccinate Synthase 1 (ADSS1) Deficient Myopathy.

The goal of this clinical trial is to evaluate the safety, tolerability and preliminary efficacy of ASA-001 in two adults diagnosed with ADSS1 deficient myopat…

Adenylosuccinate Synthase 1 Deficient Myopathy

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Cure ADSSL1NCT07412821

Phase 1

A Phase 1 Study of BAL0891 as Monotherapy and in Combination With Chemotherapy or Tislelizumab in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

This study is a multiple cohort, multicenter, open-label Phase 1 study with dose-escalation substudies investigating intravenous (IV) BAL0891 as monotherapy, a…

Advanced Solid TumorTNBC - Triple-Negative Breast CancerGastric Cancer+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

SillaJen, Inc.NCT05768932

Observational

Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction (LUTO): A Prospective Trial

The purpose of the study is to study the outcomes of maternal and fetal patients who are undergoing fetal intervention for severe isolated lower urinary tract …

Lower Urinary Tract Obstructive SyndromeLower Urinary Tract Obstruction, CongenitalBladder Outlet Obstruction+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Rodrigo RuanoNCT03281798

Phase 4

Vaginal Estradiol vs Oral Beta-3 Agonist for Treatment of Overactive Bladder Syndrome: A Single-Therapy, Double-Blind, Randomized Controlled Trial

A single site, double-blinded, randomized controlled trial for postmenopausal women with urinary frequency, urgency, nocturia with or without urgency urinary i…

Overactive Bladder Syndrome

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Walter Reed National Military Medical CenterNCT05221021

Phase 4

Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance

The purpose of this study is to examine the impact of timed cortisol release or differently timed cortisol rhythms on insulin resistance in both men and women …

Shift Work ScheduleCircadian RhythmInsulin Resistance+1 more

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Washington State UniversityNCT07494084

Phase 2

Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)

This is a Phase II clinical study for people with stage IV cancer. The study will evaluate the use of stereotactic body radiation therapy (SBRT), a type of foc…

Head and Neck CancerNon-Small Cell Lung CancerCervical Cancer+2 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Mark BernardNCT07770100

Phase 1

A Pilot Study of Lorlatinib for Treatment of Children With Newly Diagnosed High-Grade Glioma With ROS-1 (ROS Proto-Oncogene 1, Receptor Tyrosine Kinase) or ALK (Anaplastic Lymphoma Kinase) Fusion

The goal of this study is to determine the response of the study drug loratinib in treating children who are newly diagnosed high-grade glioma with a fusion in…

High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Nationwide Children's HospitalNCT06333899

Phase 1

Phase I Study of 5-Azacitidine Plus PD-1/PD-L1 Inhibitor in Patients With PD-1/PD-L1 Refractory Tumors

This is a Phase I study to determine the optimal biological dose (OBD) of 5-Azacitidine in combination with PD-1/PD-L1 inhibitors in patients with tumors refra…

Solid TumorLocally Advanced Solid TumorMetastatic Tumor

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Mohammed MilhemNCT07404332

Phase 2

Bempedoic Acid Therapy for Polycystic Kidney Disease (BEAT-PKD) Randomized Clinical Trial

Autosomal dominant polycystic kidney disease (ADPKD), the most commonly inherited kidney disease, is characterized by the development of cysts in the kidney th…

ADPKD (Autosomal Dominant Polycystic Kidney Disease)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Kenneth HallowsNCT07282821