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3,219 recruiting studies matching your filters

Phase I/II Open Label Trial of Intravenous Sodium Thiosulfate (Pedmark®) as Otoprotectant in Adults Receiving Cisplatin Chemotherapy (STOP-CIS)

The purpose of this study is to assess the safety and effectiveness of a drug called Pedmark® sodium thiosulfate (STS) in reducing hearing impairment with stan…

Solid Tumor MalignanciesTesticular CancerHead and Neck Cancer+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of ArizonaNCT07407582

Phase 1

A Phase I Study of OTS167PO, a MELK Inhibitor, to Evaluate Safety, Tolerability and Pharmacokinetics in Patients With Advanced Breast Cancer and Dose-Expansion Study in Patients With Triple Negative Breast Cancer

The purpose of this study is to determine the maximum tolerated dose (MTD) of OTS167 administered via oral capsule (PO) to patients with relapsed/refractory lo…

Relapsed/Refractory Locally Advanced or Metastatic Breast Cancer and Triple Negative Breast Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

OncoTherapy Science, Inc.NCT02926690

Phase 1

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

An open label, non-randomized study in pediatric patients with advanced high-grade gliomas and other solid tumors. The study will be performed in two phases: …

High-grade GliomaSolid Tumor, Unspecified, Child

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Laminar PharmaceuticalsNCT04299191

Phase 1

Phase I/II Trial of Gabapentin Plus Ketamine for Prevention and Treatment of Acute and Chronic Pain in Locally Advanced Head and Neck Cancer Patients Undergoing Primary or Adjuvant Chemoradiation

This is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergo…

Head and Neck CancerLocally Advanced Head and Neck Carcinoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Natalie LockneyNCT05156060

Phase 2

Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related Dementias

This study is being done to research the usefulness of PET/CT imaging for measuring brain inflammation and its relation to Alzheimer's Disease Dementia and rel…

Lewy Body Dementia (LBD)Alzheimer Dementia (AD)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Val LoweNCT04786223

Modeling Adherence to Preventive Swallowing Exercises in Head and Neck Cancer

This trial uses blood tests and questionnaires to study how well participants with head and neck cancer that has spread to other places in the body adhere to s…

Carcinoma of Unknown PrimaryClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+28 more

Phase 3

Melatonin for the Prevention of Antibiotic Associated Acute Kidney Injury

This study will evaluate the safety and effectiveness of melatonin for the prevention of antibiotic associated acute kidney injury in hospitalized patients.

Acute Kidney InjuryAdverse Drug Event

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Rutgers, The State University of New JerseyNCT05084196

Observational

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy for Pain Palliation in Head, Neck, & Brachial Cancer

This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, …

Head Neck CancerSquamous Cell Cancer of Head and Neck (SCCHN)Cancer Pain

Estimated

~$10 – $750

Actual pay is set by the research site.

University of VirginiaNCT07405645

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i (ACHIEVE-SGLT2i) Registry

This real-world, international registry aims to evaluate the current experience with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in adult congenital hea…

Adult Congenital Heart DiseaseCongenital Heart DiseaseSystemic Right Ventricle+5 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Leiden University Medical CenterNCT06932081

Phase 1

Phase 1/2A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients With Advanced Solid Tumors

The main goals of this clinical trial are to find out what the best dose of the study drug, OTP-01, is for patients with solid tumors through understanding how…

Advanced Solid Tumors

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Ottimo Pharma LimitedNCT07266428

Phase 1

A Multicenter, Open-Label, Phase 1a/b First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of BG-C0979 in Patients With Selected Advanced Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of BG-C0979 monotherapy or in comb…

Advanced Solid Tumor

Estimated

~$150 – $4,500

Actual pay is set by the research site.

BeOne MedicinesNCT07414836

Observational

SurgerySMART: Studying Melatonin and Recovery in Teens

The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep. Melatonin …

Juvenile; ScoliosisScoliosis IdiopathicScoliosis; Adolescence+5 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Stanford UniversityNCT06093477