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3,219 recruiting studies matching your filters

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial) - a Phase Ib Feasibility Trial

This is a phase 1b prospective, single arm, open-label trial determining the efficacy and feasibility of using a response-guided approach to help guide neoadju…

Gastroesophageal Adenocarcinoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of California, IrvineNCT05733689

Phase 2

A Phase 2 Study of Augmentation Cystoplasty Using an Autologous Neo-Bladder Construct In Subjects With Fibrotic Contracted Bladder

The purpose of this research study is to find out if autologous "neo-bladder" construct for the treatment of fibrotic and/or contracted bladder can improve bla…

Contracted Bladder

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT05054790

Phase 2

A Phase 2, Single-Arm Trial of Relacorilant in Combination With Nab-Paclitaxel and Gemcitabine in Chemotherapy-Naïve Patients With Metastatic Pancreatic Adenocarcinoma (TRIDENT)

This is a 2-part, Phase 2 study to evaluate the safety, tolerability, dosing, pharmacokinetics (PK), and efficacy of relacorilant in combination with nab-pacli…

AdenocarcinomaCarcinoma, Pancreatic Ductal

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Corcept TherapeuticsNCT07259317

Observational

Using Shared Decision Making to Improve Family Media Use Planning

Investigators will conduct a pilot randomized controlled trial assessing the efficacy and feasibility of the newly developed Family Media Check-In (FMC).

Adolescent Behavior

Estimated

~$10 – $750

Actual pay is set by the research site.

Seattle Children's HospitalNCT05722535

Phase 1

An Adaptive Two-Part, Phase 1/2, Multi-Center, Double-Blinded, Randomized, Controlled Study of the Safety and Efficacy of Topically Applied PEP-TISSEEL in Participants With Chronic Radiation Ulcer

The goal of this clinical trial is to learn if drug Purified Exosome Product (PEP™) and Fibrin Sealant (TISSEEL® VH SD Kit) (PEP-TISSEEL) works to treat chroni…

Chronic Radiation Ulcer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Rion Inc.NCT06793748

Phase 2

A Phase 2 Study of Atezolizumab With Selinexor in Alveolar Soft Part Sarcoma (AXIOM)

This phase II trial tests whether atezolizumab in combination with selinexor works to shrink tumors in patients with alveolar soft part sarcoma and whether the…

Advanced Alveolar Soft Part SarcomaAdvanced Soft Tissue SarcomaMetastatic Alveolar Soft Part Sarcoma+2 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05333458

Phase 4

Investigation of Locus Coeruleus Function in Sustained Attention

The norepinephrine-producing locus coeruleus (LC) is thought to be central to a wide array of cognitive functions, like attention and goal pursuit, and has bee…

Attention - no Condition is Being Assessed - Healthy Adults

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of California, DavisNCT06041048

Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance ("USOPTIVAL")

A prospective multi-center observational study. The study will enroll eligible subjects from the United States to optimize the biomarker panel and evaluate the…

Colorectal Cancer (CRC)Advanced Adenomas (AA)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Universal DiagnosticsNCT04792684

Phase 1

A Phase IA/IB Trial of Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies and HER2 Negative Breast Cancer

Leflunomide in patients with PTEN-Altered advanced solid tumors or HER2 negative breast cancer. Phase 1A objectives are to determine the safety, tolerability, …

PTEN-Altered Advanced Solid Tumors and HER2 Negative Breast Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Deborah DoroshowNCT04997993

Observational

Combining 4D MRI and 4DCT for Personalized Volumetric Motion Monitoring in Lung Radiation Therapy

The purpose of this study is to assess a real time motion tracking of lung tumors and important organs next to the tumor while breathing during a participant's…

Lung Cancer (NSCLC)Radiation

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Maryland, BaltimoreNCT07398209

Phase 1

Phase I/II Trial of Autologous Rapamycin-Resistant Th1/Tc1 (RAPA-201) Cell Therapy of PD-(L)1 Resistant Solid Tumors

The therapy of solid tumors has been revolutionized by immune therapy, in particular, approaches that activate immune T cells in a polyclonal manner through bl…

Solid TumorSmall Cell and Non-small Cell Lung CancerHead and Neck Cancer+6 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Rapa Therapeutics LLCNCT05144698

Phase 3

Phase III Study of Local or Systemic Therapy INtensification DIrected by PET in Prostate CAncer Patients With Post-ProstaTEctomy Biochemical Recurrence (INDICATE)

This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination w…

Biochemically Recurrent Prostate CarcinomaMetastatic Prostate CarcinomaProstate Adenocarcinoma+1 more

Estimated

~$50 – $2,250

Actual pay is set by the research site.

ECOG-ACRIN Cancer Research GroupNCT04423211