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3,220 recruiting studies matching your filters

A Phase 1, Open-Label, Multicenter Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment

This purpose of this study is to help to evaluate the pharmacokinetic (PK) profile of pralatrexate when administered to patients with various degrees of hepati…

Advanced Solid TumorsHematologic Malignancies

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Acrotech Biopharma Inc.NCT07036133

Phase 1

A Phase 1, Multicenter, Open-Label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors

This is a multicenter, open-label, Phase 1 study. The study will enroll subjects with advanced solid tumors. It consists of six parts. Objectives for Dose-Esca…

Advanced Solid Tumors

Estimated

~$150 – $4,200

Actual pay is set by the research site.

MediLink Therapeutics (Suzhou) Co., Ltd.NCT06384352

Phase 2

Phase II Study of Neoadjuvant Folfirinox Chemotherapy Followed by Pembrolizumab Followed by Surgery for Patients With Localized, Resectable Adenocarcinoma of the Pancreas

Abbreviated Title: Neoadjuvant FOLFIRINOX combined with Pembrolizumab followed by surgery for patients with resectable pancreatic cancer Trial Phase: Phase II …

Pancreatic Ductal Adenocarcinoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Baylor College of MedicineNCT05132504

Phase 1

A Phase I/II Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM), and Recurrent/Progressive Medulloblastoma (MB)

The primary objective will be to demonstrate the manufacturing feasibility and safety, and to determine the maximum tolerated dose (MTD) of RNA-LP vaccines in …

Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of FloridaNCT04573140

Observational

Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: Preventing Substance Use in Adversity- Impacted Youth

The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing th…

Adverse Childhood ExperiencesFamily Functioning

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, IrvineNCT06821035

A Novel Multiplex ELISA Assay for Surveilling Patients With History of Bladder Cancer

Voided urinary cytology (VUC) is the most widely used urine-based assay for detecting bladder cancer (BCa); however, it fails to detect approximately 50% of lo…

Bladder Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Cedars-Sinai Medical CenterNCT03193515

Phase 2

MC230716 Pilot Single-Arm, Pragmatic Trial Of In-Home Versus In-Clinic Subcutaneous Nivolumab Administration Through Cancer CARE (Connected Access And Remote Expertise) Beyond Walls (CCBW) Program

This phase II trial compares the impact of subcutaneous (SC) nivolumab given in an in-home setting to an in-clinic setting on cancer care and quality of life. …

Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more

Observational

A Study to Assess the Safety of Intratumoral Diffusing Alpha Radiation Emitters With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

This is a multi-center clinical study enrolling up to 50 participants. The primary objective of the study is to evaluate the safety of Alpha DaRT in combinatio…

Pancreatic CancerPancreatic AdenocarcinomaMetastatic Pancreatic Cancer

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Alpha Tau Medical LTD.NCT06698458

Phase 1

Oral Deucrictibant for the Prophylactic and Acute Treatment in Patients With Bradykinin Mediated Angioedema With Normal C1 Inhibitor (BK-AE-nC1INH)

To assess the efficacy of prophylactic treatment with deucrictibant extended release (XR) tablet versus placebo in preventing angioedema attacks, and to also a…

Hereditary Angioedema (HAE)AngioedemaBradykinin-mediated Angioedema+1 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Institute for Asthma and AllergyNCT07046806

Phase 1

A Phase 1/2 Study of REGN4018 (Ubamatamab), a MUC16×CD3 Bispecific Antibody, Administered Alone or in Combination With Cemiplimab in Patients With Recurrent Ovarian Cancer or Other Recurrent MUC16+ Cancers

The main purpose of this study is to: * Learn about the safety of ubamatamab and to find out what dose of ubamatamab can be given alone or with cemiplimab to …

Recurrent Ovarian CancerRecurrent Fallopian Tube CancerRecurrent Primary Peritoneal Cancer+3 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Regeneron PharmaceuticalsNCT03564340

Observational

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

The investigators aim to use smart-home sensors and artificial intelligence (AI) to monitor and detect Alzheimer's Disease and Related Dementias (ADRD)-specifi…

Alzheimer Disease and Related Dementias (ADRD)Mild Cognitive Impairment (MCI)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Missouri-ColumbiaNCT07120347

Phase 2

Safety and Immunological Effects of Pembrolizumab Plus Ablative Radiotherapy in Patients With Advanced Adrenocortical Carcinoma

The purpose of this study is to determine whether pembrolizumab given after standard ablative Radiotherapy is a safe treatment that causes few or mild side eff…

Adrenocortical CarcinomaACCMetastatic Adrenocortical Carcinoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT06066333