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359 recruiting studies matching your filters

Pulse Biosciences' CellFX nsPFA Cardiac Surgery Clamp System for the Treatment of Atrial Fibrillation During Concomitant Cardiac Surgery

The primary objective of this Pivotal study is to demonstrate the safety and effectiveness of the Pulse Biosciences nsPFA™ Cardiac Surgery System in treating a…

Atrial FibrillationMaze ProcedureAF+1 more

Estimated

~$10 – $8,750

Pulse Biosciences, Inc.NCT06959121

A Study to Evaluate the Safety and Efficacy of Intracranial Venous Blood Sampling for Liquid Biopsy in the Diagnosis of Brain Cancers

To learn if drawing blood directly from veins inside the brain is safe and can effectively provide the same kind of detailed information about high-grade gliom…

Intracranial Venous BloodBrain CancersLiquid Biopsy+1 more

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT07467109

Pilot Study to Evaluate the Long-term Chronic Care of Patients Who Could or do Utilize an Osseointegrated Device (OID)

The primary objective of the study is to evaluate OID hearing intervention on cognition among patients who could vs. do utilize an OID. We will also evaluate t…

Hearing Loss, ConductiveHearing Loss, MixedDeafness, Unilateral

Estimated

~$10 – $750

University of South FloridaNCT04899037

Phase 1

Efficacy of Topical Ruxolitinib in Acute Skin GVHD: A Pilot Study

The purpose of this study is to see if ruxolitinib, a Janus Kinase (JAK) 1/2 inhibitor, is safe for people who have acute skin graft versus host disease (GVHD)…

Acute Skin Graft Versus Host Disease (GVHD)

Estimated

~$10 – $5,625

Children's Hospital Medical Center, CincinnatiNCT07801248

Phase 1

NEO-COMBAT XL: Neoadjuvant and Maintenance XL092 and Cemiplimab in BRAF V600E-wildtype Anaplastic Thyroid Cancer: a Phase 1B Study

This multicenter study examines the safety and feasibility of the combination of neoadjuvant XL092 and cemiplimab prior to surgical resection in participants w…

Anaplastic Thyroid CancerThyroid CancerBRAF Mutation-Related Tumors

Estimated

~$10 – $6,250

UNC Lineberger Comprehensive Cancer CenterNCT06902376

Phase 2

Phase II Open-Label, Randomized-Controlled Trial of CSF-1R Inhibitor, Axatilimab, for Prevention of Acute and Chronic GVHD After HLA-Matched Related and Unrelated Donor Allogeneic Stem Cell Transplantation

This is a randomized, multisite, Phase II study designed to compare the 1-year GVHD-free survival of the control arm (no axatilimab) to the experimental arm (a…

Graft -Versus-host-disease

Estimated

~$10 – $6,250

Medical College of WisconsinNCT07808112

Observational

A Randomized, Open-label, Evaluator-Blinded, Cross-over Clinical Study to Confirm the Safety and Tolerability of an Ultra Absorbency Menstrual Tampon Compared to a Commercially Marketed Tampon

A Randomized, Open-Label, Evaluator-Blinded, Cross-Over Clinical Study to Confirm the Safety and Tolerability of an Ultra Absorbency Menstrual Tampon Compared …

Safety and Tolerability in Healthy Volunteers

Estimated

~$10 – $8,750

Lyv Life Inc. (dba: Cora)NCT07807891

Phase 3

A Randomized, Double-Masked, Vehicle-Controlled, Adequate and Well-Controlled Pivotal Study With Co-Primary Endpoints to Evaluate the Safety and Efficacy of d-MAPPS™ Ophthalmic Solution in Subjects With Chronic Ocular Graft-Versus-Host Disease (oGVHD)

This is a Phase III, multicenter, randomized, double-masked, vehicle-controlled, parallel-group clinical trial designed to evaluate the efficacy, safety, and t…

oGVHDOcular Graft Versus Host Disease

Estimated

~$10 – $8,750

Regenerative Ocular Immunobiologics LLCNCT07776210

Phase 2

A Phase 2 De-escalation Study of Dabrafenib and Trametinib for Patients With BRAF V600 Mutant Low-Grade Gliomas

This phase II trial studies how well de-escalating the drugs dabrafenib and trametinib works in treating patients with low-grade gliomas that have a BRAF V600 …

BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07110246

Observational

EVERYVET (Empowering VEterans in Research effectivelY Using Virtual Engagement Tools): A Patient-Centered Study

Cardiovascular disease is the leading cause of death among Veterans. Clinical trials are essential for developing better treatments, but Veterans remain underr…

Atrial Fibrillation (AF)Cardiovascular Diseases

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07741955

Phase 1

A Phase 1 Randomized, Double-blind, Placebo-controlled, Crossover Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single-dose of ASY202 in Adults With Asthma

This is a phase 1 study, randomized, double-blind, placebo-controlled, 2 treatment, 2 period crossover study to evaluate the pharmacokinetics, safety, and tole…

Safety in Asthma Patients

Estimated

~$10 – $8,750

Aspeya, Inc.NCT07665892

Long-Term Evaluation and Follow Up Care of Patients Treated With Allogeneic Stem Cell Transplants

This study will provide follow-up evaluation and care of patients who have undergone allogeneic (donor) stem cell transplantation at the NIH Clinical Center. P…

Graft-versus-leukemiaGraft vs Host DiseaseGraft Rejection

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT00106925