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224 recruiting studies matching your filters

Effects of N-Acetyl-L-Leucine on CACNA1A Disorders: A Phase III, Randomized, Placebo-controlled, Double-blind, Crossover Study

A pivotal, randomized, double-blind, placebo-controlled, multi-center therapeutic study for patients age 4 and older with a confirmed diagnosis of CACNA1A. The…

CACNA1ASpinocerebellar Ataxia Type 6Episodic Ataxia Type 2+1 more

Estimated

~$10 – $8,750

IntraBio IncNCT07221292

Natural History Study of Patients With Excess Androgen

This study will evaluate and gather information in patients with genetic causes of too much androgen (male-like hormone) in order to better understand the effe…

Congenital Adrenal Hyperplasia (CAH)Familial Male-Limited Precocious Puberty (FMPP)

Estimated

~$10 – $675

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT00250159

Observational

Hospital-to-Home Care Coordination for Children and Youth With Special Health Care Needs

Aim 1: Compare the effectiveness of focused dose vs extended dose hospital-to-home Transitional Care Interventions (H2H-TCI) on health service use and parent-r…

Health CarePediatricsTransitional Care+2 more

Estimated

~$10 – $6,250

Duke UniversityNCT06428175

International Rapid-onset Obesity With Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) REDCap Registry

The Center for Autonomic Medicine in Pediatrics (CAMP) has collaborated with doctors from around the world to build the first International ROHHAD (Rapid-onset…

ROHHADRapid-Onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation

Estimated

~$10 – $1,125

Ilya KhaytinNCT03135730

Phase 4

Vitamin D Homeostasis in Sarcoidosis

This study evaluates the relationship between vitamin-D status and severity of sarcoidosis, and the effects of vitamin-D repletion in vitamin-D insufficient pa…

SarcoidosisVitamin D Insufficiency

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT03621553

Phase 1

Open-label, Phase 1b, Single Ascending Dose Study to Evaluate the Safety of VERVE-102 Administered to Patients With Heterozygous Familial Hypercholesterolemia or Premature Coronary Artery Disease Who Require Additional Lowering of Low-density Lipoprotein Cholesterol

VT-10201 is an Open-label, Phase 1b, Single-ascending Dose Study That Will Evaluate the Safety of VERVE-102 Administered to Patients With Heterozygous Familial…

Heterozygous Familial HypercholesterolemiaPremature Coronary Heart Disease

Estimated

~$10 – $8,750

Verve Therapeutics, Inc.NCT06164730

Phase 2

Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults: A Randomized Control Trial

The purpose of this research is to see if ketamine is effective and safe in treating children and young adults with sickle cell disease experiencing sickle cel…

Sickle Cell DiseaseVaso-Occlusive Pain Episode in Sickle Cell DiseaseKetamine Infusion+2 more

Estimated

~$10 – $7,500

Mohsen SaidinejadNCT07369024

Biofluid Research on Age-Related or Inherited Neurodegeneration (BRAIN)

The aim of this study is to contribute to and continue to sustain a repository of blood samples, nucleic acid (DNA and/or RNA) samples, family history informat…

Frontotemporal Degeneration (FTD)ALS (Amyotrophic Lateral Sclerosis)Primary Progressive Aphasia (PPA)+12 more

Estimated

~$10 – $750

University of PennsylvaniaNCT07798700

Observational

Anti-inflammatory Activities of Vitamin C Supplementation on the Gut Barrier Function in Adults With Obesity

This study is testing whether taking vitamin C every day can help improve gut health and reduce inflammation in adults with obesity. Poor gut health-sometimes …

Adequate Vitamin C StatusInadequate Vitamin C Status

Estimated

~$10 – $6,250

Ohio State UniversityNCT07151105

Identifying Subclinical Transthyretin Cardiac Amyloidosis in Asymptomatic Carriers of the V122I TTR Allele

Approximately 1.5 million of the 44 million Blacks in the United States are carriers of the valine-to-isoleucine substitution at position 122 (V122I) in the tr…

Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more

Estimated

~$10 – $750

University of Texas Southwestern Medical CenterNCT05489549

Phase 1

The Low-Down on Methamphetamine Isomers: Prevalence and Pharmacology in Humans

This study is being done to understand the metabolism and impairment profile of methamphetamine (meth). Meth exists as two chemical structures that are mirror …

Methamphetamine

Estimated

~$10 – $6,250

University of Wisconsin, MadisonNCT06746831

Phase 2

Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients Receiving Neoadjuvant Chemotherapy for Operable Triple Negative Breast Cancer

A two arm pilot study investigating the rate of pathologic complete response in patients with vitamin D deficiency and triple negative breast cancer undergoing…

Triple Negative Breast CancerVitamin D DeficiencyInvasive Breast Cancer

Estimated

~$10 – $6,250

Wake Forest University Health SciencesNCT04677816