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Phase 1
A Phase 1/2a, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Evidence of Antitumor Activity of JAB-2485 in Adult Patients With Advanced Solid Tumors
This study is to evaluate the safety and tolerability of JAB-2485 monotherapy in adult participants with advanced solid tumors.
Solid TumorsER+ Breast CancerTriple Negative Breast Cancer, TNBC+2 more
Jacobio Pharmaceuticals Co., Ltd.NCT05490472
Phase 2
A Phase 2 Study of Avelumab in Combination With ATR Inhibitor M1774 in Patients With ARID1A-mutated Recurrent Endometrial Cancer Who Have Received Prior Immunotherapy
The purpose of this research study is to see if the combination of study drugs avelumab and M1774 is effective and safe for participants with endometrial cance…
Endometrial CancerARID1A Gene MutationRecurrent Endometrial Carcinoma
Panagiotis Konstantinopoulos, MD, PhDNCT06518564