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1,574 recruiting studies matching your filters

Postoperative Pacing for Cardiac Efficiency

The goal of this study is to determine whether temporarily increasing a child's heart rate after heart surgery can improve blood flow and oxygen supply to the …

Pacing TherapyPostoperative CarePediatric Congenital Heart Surgery+2 more

Estimated

~$10 – $7,500

Robert G. Webster, MD, MPHNCT07852390

Phase 3

An Open-label Long-term Follow-up Study to Evaluate the Effects of Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH (MK-7962-038)

Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. Th…

Pulmonary Arterial Hypertension

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07218029

Surgery as a Treatment for Medically Intractable Epilepsy

Background: \- Drug resistant epilepsy is the term used to describe epilepsy that cannot be controlled by medication. Many people whose seizures do not respon…

EpilepsyEpilepsy, Temporal LobePartial Epilepsy

Estimated

~$10 – $675

National Institute of Neurological Disorders and Stroke (NINDS)NCT01273129

Phase 1

Temporal Interference for Thalamocortical Activity and Network Modulation

The goal of this clinical trial is to find out whether a type of electrical brain stimulation, called temporal interference stimulation, can temporarily change…

Healthy Participants

Estimated

~$10 – $6,250

University of Wisconsin, MadisonNCT07219719

Observational

A Randomized Placebo-procedure Controlled Trial of the Multi-Pole Pulmonary Artery Radiofrequency Ablation Enhancor System PULmonary Artery Denervation Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

The goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiof…

Pulmonary HypertensionHeart Failure With Reduced Ejection FractionHypertension+5 more

Estimated

~$10 – $8,750

Pulnovo Medical, Inc.NCT07214376

Investigating Epilepsy: Screening and Evaluation

Background: Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want peo…

SeizuresEpilepsyEpilepsy, Temporal Lobe+1 more

Estimated

~$10 – $675

National Institute of Neurological Disorders and Stroke (NINDS)NCT03478852

Phase 3

EASi-HF Preserved - A Phase III Double-blind, Randomised, Parallel-group Superiority Trial to Evaluate Efficacy and Safety of the Combined Use of Oral Vicadrostat (BI 690517) and Empagliflozin Compared With Placebo and Empagliflozin in Participants With Symptomatic Heart Failure (HF: NYHA II-IV) and Left Ventricular Ejection Fraction (LVEF) ≥40%

This study is open to adults aged 18 or above legal age with heart failure. People can join the study if they have heart failure symptoms and a left ventricula…

Heart Failure

Estimated

~$10 – $7,500

Boehringer IngelheimNCT06424288

Phase 2

A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial Hypertension

Background: \- High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. In spite of recent advances in treatment,…

Pulmonary Arterial Hypertension

Estimated

~$10 – $5,625

National Institutes of Health Clinical Center (CC)NCT01712620

Studies of the Natural History of Rheumatic Diseases

This study will explore the causes of rheumatic diseases and why many of them affect certain minority communities more severely. Rheumatic diseases may cause j…

Rheumatic DiseasesArthritis

Estimated

~$10 – $675

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT00024479

Phase 3

A Phase III, Randomised, Double-blind Study to Evaluate the Effect of Balcinrenone/Dapagliflozin, Compared With Dapagliflozin, on the Risk of Heart Failure Events and Cardiovascular Death in Patients With Heart Failure and Impaired Kidney Function

This is a Phase III, international, multi-centre, randomised, double-blind, parallel-group, double-dummy, active-controlled, event-driven study in patients wit…

Heart Failure and Impaired Kidney Function

Estimated

~$10 – $7,500

AstraZenecaNCT06307652

Observational

Cognitive Neurocomputational Task Reliability & Clinical Applications Consortium

In Study 1, investigators will test the ability of each of the seven paradigms to differentiate between schizophrenia (SZ)/schizoaffective disorder (SZA) and m…

SCHIZOPHRENIA 1 (Disorder)Schizoaffective DisorderHealthy Adult Participants

Estimated

~$10 – $6,250

Washington University School of MedicineNCT07853807

Phase 4

An Open-label Study to Evaluate the Safety and Tolerability of LIQ861 in Participants With WHO Group 1 PAH Transitioning From Oral Selexipag to Inhaled Treprostinil

This study will look at safety and tolerability of LIQ861 (treprostinil) inhalation powder in adults with pulmonary arterial hypertension (PAH, WHO Group 1) wh…

Pulmonary Arterial Hypertension (PAH)

Estimated

~$10 – $8,750

Liquidia Technologies, Inc.NCT07759804