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1,574 recruiting studies matching your filters

Diagnosis and Treatment of Patients With Inborn Errors of Metabolism or Other Genetic Disorders

Researchers intend on diagnosing and treating certain inborn errors of metabolism. By doing this researchers hope to expand their knowledge about these disorde…

Arterial Calcification Due to Deficiency of CD73

Estimated

~$10 – $675

National Human Genome Research Institute (NHGRI)NCT00369421

Phase 3

A Study to Investigate the Efficacy and Safety of Orforglipron Once Daily in Participants With Peripheral Artery Disease: A Randomized, Double-Blind, Placebo Controlled Trial

The purpose of this study is to evaluate the effect and safety of orforglipron once daily in participants with Fontaine II peripheral arterial disease (PAD). P…

Peripheral Arterial Disease

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07223593

Phase 1

A Feasibility Phase I Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

Background: A type of drug called monoclonal antibody immune checkpoint inhibitors are often used in cancer treatment. These drugs help the body s immune syst…

Locally Advanced Alveolar Soft Part SarcomaMetastatic Alveolar Soft Part SarcomaLocally Advanced Non Small Cell Lung Cancer+7 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06066138

Observational

Risk Evaluation With AI-CPA to Reduce Progression and Improve Lifetime Care for Patients With Known Coronary Artery Disease

REWRITE-CAD is a prospective, randomized, multi-center trial assessing the management of asymptomatic participants with a history of PCI or MI who will undergo…

CAD - Coronary Artery Disease

Estimated

~$10 – $8,750

HeartFlow, Inc.NCT07834372

Phase 2

A Randomized, Multicenter, Double-Blind, Parallel, Placebo-controlled Phase 2b Clinical Trial to Evaluate the Efficacy and Safety of YN001 in Adults With Coronary Atherosclerosis

This study is designed to evaluate the efficacy and safety of intravenously administered YN001 in patients diagnosed with coronary atherosclerosis, who are rec…

AtherosclerosisCoronary Artery Disease

Estimated

~$10 – $8,750

Beijing Inno Medicine Co., Ltd.NCT07521007

Phase 1

A Phase 1/2a, Open-label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and the preliminary evidence of disease-modify…

Arthritis, Rheumatoid

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07412704

Phase 3

A Master Protocol for Phase 3 Randomized, Double-Blind, Placebo-Controlled Studies to Investigate the Efficacy and Safety of Once Weekly Eloralintide in Adult Participants With Osteoarthritis Knee Pain, and Obesity or Overweight (ENLIGHTEN-4)

The YDAN master protocol will support two independent studies, J3R-MC-YOA1 and J3R-MC-YOA2. Each study will investigate how well and safely Eloralintide (LY384…

OsteoarthritisOverweight or Obesity

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07353931

Phase 4

Pioglitazone, Lipotoxicity, and Heart Failure With Preserved Ejection Fraction (HFpEF)

Our goal of the study is to learn the effects of the diabetes medication named Pioglitazone, in type-2 diabetic obese participants with Heart failure. The main…

Type 2 Diabetes Mellitus in ObeseHeart Failure With Preserved Ejection Fraction

Estimated

~$10 – $6,250

The University of Texas Health Science Center at San AntonioNCT05838287

Observational

Confirmation of Values and Preferences When Considering a Musculoskeletal Diagnostic Test: A Scenario-Based Study

The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon prob…

Non-traumatic Musculoskeletal ConditionsCarpal Tunnel Syndrome (CTS)Lateral Epicondylitis+5 more

Estimated

~$10 – $6,250

University of Texas at AustinNCT07158892

Phase 2

A Phase 2, Multicenter, Platform Study of Targeted Therapies for the Treatment of Adult Subjects With Moderately to Severely Active Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. This study will evaluate the efficacy…

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction: Randomized Controlled Feasibility Trial - The Rebalance HF Study

The purpose of this clinical study is to evaluate the safety and early effectiveness of a catheter-based procedure that treats a nerve called the right greater…

Heart Failure With Preserved Ejection Fraction (HFpEF

Estimated

~$10 – $8,750

Axon Therapies, Inc.NCT04592445

Phase 2

A Phase II, Multicenter, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have an Inadequate Response or Intolerance to TNF and/or JAK Inhibitors

This study will assess the efficacy and safety of Afimkibart (also known as RO7790121) compared with placebo in participants with moderate to severe rheumatoid…

Rheumatoid Arthritis

Estimated

~$10 – $7,500

Hoffmann-La RocheNCT07137598